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Volumn 5, Issue 1, 2010, Pages

Enhanced selection of high affinity DNA-reactive B cells following cyclophosphamide treatment in mice

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; B CELL ACTIVATING FACTOR; CYCLOPHOSPHAMIDE; DEOXYRIBONUCLEASE; DNA ANTIBODY; DNA;

EID: 77649117940     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008418     Document Type: Article
Times cited : (25)

References (33)
  • 2
    • 0029933460 scopus 로고    scopus 로고
    • Pathogenic autoantibodies are routinely generated during the response to foreign antigen: A paradigm for autoimmune disease
    • Ray SK, Putterman C, Diamond B (1996) Pathogenic autoantibodies are routinely generated during the response to foreign antigen: a paradigm for autoimmune disease. Proc Natl Acad Sci U S A 93: 2019-2024.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 2019-2024
    • Ray, S.K.1    Putterman, C.2    Diamond, B.3
  • 3
    • 0031424315 scopus 로고    scopus 로고
    • Receptor editing in a transgenic mouse model: Site, efficiency, and role in B cell tolerance and antibody diversification
    • Pelanda R, Schwers S, Sonoda E, Torres RM, Nemazee D, et al. (1997) Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification. Immunity 7: 765-775.
    • (1997) Immunity , vol.7 , pp. 765-775
    • Pelanda, R.1    Schwers, S.2    Sonoda, E.3    Torres, R.M.4    Nemazee, D.5
  • 4
    • 0041689676 scopus 로고    scopus 로고
    • Predominant autoantibody production by early human B cell precursors
    • Wardemann H, Yurasov S, Schaefer A, Young JW, Meffre E, et al. (2003) Predominant autoantibody production by early human B cell precursors. Science 301: 1374-1377.
    • (2003) Science , vol.301 , pp. 1374-1377
    • Wardemann, H.1    Yurasov, S.2    Schaefer, A.3    Young, J.W.4    Meffre, E.5
  • 5
    • 0030273212 scopus 로고    scopus 로고
    • Selective mitomycin C and cyclophosphamide induction of apoptosis in differentiating B lymphocytes compared to T lymphocytes in vivo
    • Hemendinger RA, Bloom SE (1996) Selective mitomycin C and cyclophosphamide induction of apoptosis in differentiating B lymphocytes compared to T lymphocytes in vivo. Immunopharmacology 35: 71-82.
    • (1996) Immunopharmacology , vol.35 , pp. 71-82
    • Hemendinger, R.A.1    Bloom, S.E.2
  • 6
    • 0031027819 scopus 로고    scopus 로고
    • Ongoing immunologic activity after short courses of pulse cyclophosphamide in the NZB/ W murine model of systemic lupus erythematosus
    • Austin HA 3rd, Patel AD, Cadena CA, Boumpas DT, Balow JE (1997) Ongoing immunologic activity after short courses of pulse cyclophosphamide in the NZB/ W murine model of systemic lupus erythematosus. J Rheumatol 24: 61-68.
    • (1997) J Rheumatol , vol.24 , pp. 61-68
    • Austin 3rd, H.A.1    Patel, A.D.2    Cadena, C.A.3    Boumpas, D.T.4    Balow, J.E.5
  • 7
    • 16544377007 scopus 로고    scopus 로고
    • Treatment of SLE with anti-CD20 monoclonal antibody
    • Looney RJ, Anolik J, Sanz I (2005) Treatment of SLE with anti-CD20 monoclonal antibody. Curr Dir Autoimm 8: 193-205.
    • (2005) Curr Dir Autoimm , vol.8 , pp. 193-205
    • Looney, R.J.1    Anolik, J.2    Sanz, I.3
  • 8
    • 31544445804 scopus 로고    scopus 로고
    • B-cell targeted therapies in rheumatoid arthritis and systemic lupus erythematosus
    • Eisenberg R, Albert D (2006) B-cell targeted therapies in rheumatoid arthritis and systemic lupus erythematosus. Nat Clin Pract Rheumatol 2: 20-27.
    • (2006) Nat Clin Pract Rheumatol , vol.2 , pp. 20-27
    • Eisenberg, R.1    Albert, D.2
  • 9
    • 28544449032 scopus 로고    scopus 로고
    • B-cell depletion in the treatment of patients with systemic lupus erythematosus: A longitudinal analysis of 24 patients
    • Leandro MJ, Cambridge G, Edwards JC, Ehrenstein MR, Isenberg DA (2005) B-cell depletion in the treatment of patients with systemic lupus erythematosus: a longitudinal analysis of 24 patients. Rheumatology 44: 1542-1545.
    • (2005) Rheumatology , vol.44 , pp. 1542-1545
    • Leandro, M.J.1    Cambridge, G.2    Edwards, J.C.3    Ehrenstein, M.R.4    Isenberg, D.A.5
  • 10
    • 36849090653 scopus 로고    scopus 로고
    • Depletion of B cells in murine lupus: Efficacy and resistance
    • Ahuja A, Shupe J, Dunn R, Kashgarian M, Kehry MR, et al. (2007) Depletion of B cells in murine lupus: efficacy and resistance. J Immunol 179: 3351-3361.
    • (2007) J Immunol , vol.179 , pp. 3351-3361
    • Ahuja, A.1    Shupe, J.2    Dunn, R.3    Kashgarian, M.4    Kehry, M.R.5
  • 11
    • 46849096714 scopus 로고    scopus 로고
    • B cell depletion therapy in systemic lupus erythematosus: Relationships among serum B lymphocyte stimulator levels, autoantibody profile and clinical response
    • Cambridge G, Isenberg DA, Edwards J, Leandro MJ, Migone TS, et al. (2007) B cell depletion therapy in systemic lupus erythematosus: relationships among serum B lymphocyte stimulator levels, autoantibody profile and clinical response. Ann Rheum Dis 67: 1011-1016.
    • (2007) Ann Rheum Dis , vol.67 , pp. 1011-1016
    • Cambridge, G.1    Isenberg, D.A.2    Edwards, J.3    Leandro, M.J.4    Migone, T.S.5
  • 12
    • 0029004818 scopus 로고
    • Systemic lupus erythematosus: Emerging concepts. Part 1: Renal, neuropsychiatric, cardiovascular, pulmonary, and hematologic disease
    • Boumpas DT, Austin HA 3rd, Fessler BJ, Balow JE, Klippel JH, et al. (1995) Systemic lupus erythematosus: emerging concepts. Part 1: Renal, neuropsychiatric, cardiovascular, pulmonary, and hematologic disease. Ann Int Med 122: 940-950.
    • (1995) Ann Int Med , vol.122 , pp. 940-950
    • Boumpas, D.T.1    Austin 3rd, H.A.2    Fessler, B.J.3    Balow, J.E.4    Klippel, J.H.5
  • 13
    • 0023115073 scopus 로고
    • Changes in lymphocyte subsets after treatment with cyclophosphamide and during the development of contact sensitivity in the guinea pig
    • Baker D, Karcher K, Antoniou AV, Turk JL, Tan BT, et al. (1987) Changes in lymphocyte subsets after treatment with cyclophosphamide and during the development of contact sensitivity in the guinea pig. Int J Immunopharm 9: 175-183.
    • (1987) Int J Immunopharm , vol.9 , pp. 175-183
    • Baker, D.1    Karcher, K.2    Antoniou, A.V.3    Turk, J.L.4    Tan, B.T.5
  • 15
    • 0034646432 scopus 로고    scopus 로고
    • Estrogen up-regulates Bcl-2 and blocks tolerance induction of naive B cells
    • Bynoe MS, Grimaldi CM, Diamond B (2000) Estrogen up-regulates Bcl-2 and blocks tolerance induction of naive B cells. Proc Natl Acad Sci USA 97: 2703-2708.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 2703-2708
    • Bynoe, M.S.1    Grimaldi, C.M.2    Diamond, B.3
  • 16
    • 33644505807 scopus 로고    scopus 로고
    • Hormonal regulation of B cell development: 17 beta-estradiol impairs negative selection of high-affinity DNA-reactive B cells at more than one developmental checkpoint
    • Grimaldi CM, Jeganathan V, Diamond B (2006) Hormonal regulation of B cell development: 17 beta-estradiol impairs negative selection of high-affinity DNA-reactive B cells at more than one developmental checkpoint. J Immunol 176: 2703-2710.
    • (2006) J Immunol , vol.176 , pp. 2703-2710
    • Grimaldi, C.M.1    Jeganathan, V.2    Diamond, B.3
  • 17
    • 33644845552 scopus 로고    scopus 로고
    • Cutting Edge: Hormonal milieu, not antigenic specificity, determines the mature phenotype of autoreactive B cells
    • Venkatesh J, Peeva E, Xu X, Diamond B (2006) Cutting Edge: Hormonal milieu, not antigenic specificity, determines the mature phenotype of autoreactive B cells. J Immunol 176: 3311-3314.
    • (2006) J Immunol , vol.176 , pp. 3311-3314
    • Venkatesh, J.1    Peeva, E.2    Xu, X.3    Diamond, B.4
  • 18
    • 0036533385 scopus 로고    scopus 로고
    • BAFFled B cells survive and thrive: Roles of BAFF in B-cell development
    • Rolink AG, Melchers F (2002) BAFFled B cells survive and thrive: roles of BAFF in B-cell development. Curr Opin Immunol 14: 266-275.
    • (2002) Curr Opin Immunol , vol.14 , pp. 266-275
    • Rolink, A.G.1    Melchers, F.2
  • 19
    • 0035860559 scopus 로고    scopus 로고
    • An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway
    • Schiemann B, Gommerman JL, Vora K, Cachero TG, Shulga-Morskaya S, et al. (2001) An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Science 293: 2111-2114.
    • (2001) Science , vol.293 , pp. 2111-2114
    • Schiemann, B.1    Gommerman, J.L.2    Vora, K.3    Cachero, T.G.4    Shulga-Morskaya, S.5
  • 20
    • 0035860466 scopus 로고    scopus 로고
    • BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF
    • Thompson JS, Bixler SA, Qian F, Vora K, Scott ML, et al. (2001) BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science 293: 2108-2111.
    • (2001) Science , vol.293 , pp. 2108-2111
    • Thompson, J.S.1    Bixler, S.A.2    Qian, F.3    Vora, K.4    Scott, M.L.5
  • 21
    • 0034694088 scopus 로고    scopus 로고
    • BAFF mediates survival of peripheral immature B lymphocytes
    • Batten M, Groom J, Cachero TG, Qian F, Schneider P, et al. (2000) BAFF mediates survival of peripheral immature B lymphocytes. J Exp Med 192: 1453-1466.
    • (2000) J Exp Med , vol.192 , pp. 1453-1466
    • Batten, M.1    Groom, J.2    Cachero, T.G.3    Qian, F.4    Schneider, P.5
  • 22
    • 2942518502 scopus 로고    scopus 로고
    • Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches
    • Thien M, Phan TG, Gardam S, Amesbury M, Basten A, et al. (2004) Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches. Immunity 20: 785-798.
    • (2004) Immunity , vol.20 , pp. 785-798
    • Thien, M.1    Phan, T.G.2    Gardam, S.3    Amesbury, M.4    Basten, A.5
  • 23
    • 34047177483 scopus 로고    scopus 로고
    • Tolerance and efficacy of rituximab and changes in serum B cell biomarkers in patients with systemic complications of primary Sjogren's syndrome
    • Seror R, Sordet C, Guillevin L, Hachulla E, Masson C, et al. (2007) Tolerance and efficacy of rituximab and changes in serum B cell biomarkers in patients with systemic complications of primary Sjogren's syndrome. Ann Rheum Dis 66: 351-357.
    • (2007) Ann Rheum Dis , vol.66 , pp. 351-357
    • Seror, R.1    Sordet, C.2    Guillevin, L.3    Hachulla, E.4    Masson, C.5
  • 24
    • 33644660402 scopus 로고    scopus 로고
    • Similarities and differences between selective and nonselective BAFF blockade in murine SLE
    • Ramanujam M, Wang X, Huang W, Liu Z, Schiffer L, et al. (2006) Similarities and differences between selective and nonselective BAFF blockade in murine SLE. J Clin Invest 116: 724-734.
    • (2006) J Clin Invest , vol.116 , pp. 724-734
    • Ramanujam, M.1    Wang, X.2    Huang, W.3    Liu, Z.4    Schiffer, L.5
  • 25
    • 0029851318 scopus 로고    scopus 로고
    • The treatment of systemic lupus erythematosus (SLE) in NZB/W F1 hybrid mice; studies with recombinant murine DNase and with dexamethasone
    • Macanovic M, Sinicropi D, Shak S, Baughman S, Thiru S, et al. (1996) The treatment of systemic lupus erythematosus (SLE) in NZB/W F1 hybrid mice; studies with recombinant murine DNase and with dexamethasone. Clin Exp Immunol 106: 243-252.
    • (1996) Clin Exp Immunol , vol.106 , pp. 243-252
    • Macanovic, M.1    Sinicropi, D.2    Shak, S.3    Baughman, S.4    Thiru, S.5
  • 26
    • 0031779647 scopus 로고    scopus 로고
    • DNAse treatment does not improve the survival of lupus prone (NZB6NZW) F1 mice
    • Verthelyi D, Dybdal N, Elias KA, Klinman DM (1998) DNAse treatment does not improve the survival of lupus prone (NZB6NZW) F1 mice. Lupus 7: 223-230.
    • (1998) Lupus , vol.7 , pp. 223-230
    • Verthelyi, D.1    Dybdal, N.2    Elias, K.A.3    Klinman, D.M.4
  • 27
    • 54049118503 scopus 로고    scopus 로고
    • Upregulation of Antiphospholipid Antibodies Following Cyclophosphamide Therapy in Patients with Systemic Lupus Erythematosus
    • Vlachoyiannopoulos PG, Toya SP, Katsifis G, Zintzaras E, Tzioufas AG, et al. (2008) Upregulation of Antiphospholipid Antibodies Following Cyclophosphamide Therapy in Patients with Systemic Lupus Erythematosus. J Rheumatol 35: 1768-1775.
    • (2008) J Rheumatol , vol.35 , pp. 1768-1775
    • Vlachoyiannopoulos, P.G.1    Toya, S.P.2    Katsifis, G.3    Zintzaras, E.4    Tzioufas, A.G.5
  • 28
    • 65449176044 scopus 로고    scopus 로고
    • Cutting Edge: The PTPN22 allelic variant associated with autoimmunity impairs B cell signaling
    • Arechiga AF, Habib T, He Y, Zhang X, Zhang AY, et al. (2009) Cutting Edge: The PTPN22 allelic variant associated with autoimmunity impairs B cell signaling. J Immunol 182: 3343-3347.
    • (2009) J Immunol , vol.182 , pp. 3343-3347
    • Arechiga, A.F.1    Habib, T.2    He, Y.3    Zhang, X.4    Zhang, A.Y.5
  • 30
    • 33645955276 scopus 로고    scopus 로고
    • Effect of cell:cell competition and BAFF expression on peripheral B cell tolerance and B-1 cell survival in transgenic mice expressing a low level of Igkappa-reactive macroself antigen
    • Ait-Azzouzene D, Gavin AL, Skog P, Duong B, Nemazee D (2006) Effect of cell:cell competition and BAFF expression on peripheral B cell tolerance and B-1 cell survival in transgenic mice expressing a low level of Igkappa-reactive macroself antigen. Eur J Immunol 36: 985-996.
    • (2006) Eur J Immunol , vol.36 , pp. 985-996
    • Ait-Azzouzene, D.1    Gavin, A.L.2    Skog, P.3    Duong, B.4    Nemazee, D.5
  • 31
    • 0028064578 scopus 로고
    • Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire
    • Cyster JG, Hartley SB, Goodnow CC (1994) Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire. Nature 371: 389-395.
    • (1994) Nature , vol.371 , pp. 389-395
    • Cyster, J.G.1    Hartley, S.B.2    Goodnow, C.C.3
  • 32
    • 67649197343 scopus 로고    scopus 로고
    • Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus
    • Doreau A, Belot A, Bastid J, Riche B, Trescol-Biemont MC, et al. (2009) Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus. Nat Immunol 10: 778-785.
    • (2009) Nat Immunol , vol.10 , pp. 778-785
    • Doreau, A.1    Belot, A.2    Bastid, J.3    Riche, B.4    Trescol-Biemont, M.C.5
  • 33
    • 15944410592 scopus 로고    scopus 로고
    • Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide
    • Lutsiak ME, Semnani RT, De Pascalis R, Kashmiri SV, Schlom J, et al. (2005) Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide. Blood 105: 2862-2868.
    • (2005) Blood , vol.105 , pp. 2862-2868
    • Lutsiak, M.E.1    Semnani, R.T.2    De Pascalis, R.3    Kashmiri, S.V.4    Schlom, J.5


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