Study the effect of a pseudo-carrier on pharmacokinetics of 9-fluoropropyl-(+)-dihydrotetrabenazine in rat plasma by ultra-performance liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 7-8, 2011, Pages 505-510

  Zhou, Xue ^a   Qiao, Jinping ^a   Yin, Wei ^a   Zhu, Lin ^a   Kung, Hank F ^b  

^a BEIJING NORMAL UNIVERSITY   (China)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

AV 133; PET imaging agents; Pharmacokinetics; Positron emission tomography; UPLC MS MS

Indexed keywords

ACQUITY; ANALYTES; AV-133; CALIBRATION CURVES; DIHYDROTETRABENAZINE; EXTERNAL CALIBRATION; GRADIENT ELUTION; MONITORING MODE; PET IMAGING; POSITIVE MODE; PROTEIN PRECIPITATION; RAT PLASMA; TANDEM MASS SPECTROMETRIC; ULTRAPERFORMANCE LIQUID CHROMATOGRAPHY; UPLC-MS/MS;

CALIBRATION; CHROMATOGRAPHIC ANALYSIS; ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; PHARMACOKINETICS; PLASMA (HUMAN); POSITRONS;

POSITRON EMISSION TOMOGRAPHY;

AV 133; AV 149; FUSED CARBON NITROGEN HETEROCYCLE; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CALIBRATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG ISOLATION; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; MALE; NONHUMAN; PRECIPITATION; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; AREA UNDER CURVE; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; FLUORINE RADIOISOTOPES; LEAST-SQUARES ANALYSIS; MALE; POSITRON-EMISSION TOMOGRAPHY; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TETRABENAZINE;

RATTUS;

EID: 79951675294     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.01.011     Document Type: Article

References (17)

1. Pysz M.A., Gambhir S.S., Willmann J.K. Clin. Radiol. 2010, 65:500.
2. Agdeppa E.D., Spilker M.E. AAPS J. 2009, 11:286.
3. Vallabhajosula S., Killeen R.P., Osborne J.R. Semin. Nucl. Med. 2010, 40:220.
4. Tolmachev V., Stone-Elander S. Biochim. Biophys. Acta-Gen. Subj. 2010, 1800:487.
5. Eichenbaum G., Johnson M., Kirkland D., O'Neill P., Stellar S., Bielawne J., DeWire R., Areia D., Bryant S., Weiner S., Desai-Krieger D., Guzzie-Peck P., Evans D.C., Tonelli A. Regul. Toxicol. Pharmacol. 2009, 55:33.
6. Zhu L., Liu Y.J., Plossl K., Lieberman B., Liu J.Y., Kung H.F. Nucl. Med. Biol. 2010, 37:133.
7. Okamura N., Villemagne V.L., Drago J., Pejoska S., Dhamija R.K., Mulligan R.S., Ellis J.R., Ackermann U., O'Keefe G., Jones G., Kung H.F., Pontecorvo M.J., Skovronsky D., Rowe C.C. J. Nucl. Med. 2010, 51:223.
8. Tsao H.H., Lin K.J., Juang J.H., Skovronsky D.M., Yen T.C., Wey S.P., Kung M.P. Nucl. Med. Biol. 2010, 37:413.
9. Kilbourn M.R., Hockley B., Lee L., Hou C., Goswami R., Ponde D.E., Kung M.P., Kung H.F. Nucl. Med. Biol. 2007, 34:233.
10. Kung M.P., Hou C., Goswami R., Ponde D.E., Kilbourn M.R., Kung H.F. Nucl. Med. Biol. 2007, 34:239.
11. USFDA, 2001. http://www.fda.gov/cder/guidance/4252fnl.pdf.
12. Shah V.P., Midha K.K., Findlay J.W., Hill H.M., Hulse J.D., McGilveray I.J., McKay G., Miller K.J., Patnaik R.N., Powell M.L., Tonelli A., Viswanathan C.T., Yacobi A. Pharm. Res. 2000, 17:1551.
13. Viswanathan C.T., Bansal S., Booth B., DeStefano A.J., Rose M.J., Sailstad J., Shah V.P., Skelly J.P., Swann P.G., Weiner R. Pharm. Res. 2007, 24:1962.
14. Qin F., Li N., Qin T., Zhang Y., Li F.M. J. Chromatogr. B 2010, 878:689.
15. Zhang Y., Tang X., Liu X..L., Li F., Lin X. Anal. Chim. Acta 2008, 610:224.
16. Ong E.S., Ong C.N. Rapid Commun. Mass Spectrom. 2007, 21:589.
17. Kilian B., Oertel R., Kirch W. J. Chromatogr. A 2008, 1189:339.