Pharmacokinetics of [18F]fluoroalkyl derivatives of dihydrotetrabenazine in rat and monkey brain

Nuclear Medicine and Biology

Volumn 34, Issue 3, 2007, Pages 233-237

  Kilbourn, Michael R ^a   Hockley, Brian ^a   Lee, Lihsueh ^a   Hou, Catherine ^b   Goswami, Rajesh ^b   Ponde, Datta E ^b   Kung, Mei Ping ^b   Kung, Hank F ^b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

emission computed; Tetrabenazine; Tomography; Vesicular monoamine transporter

Indexed keywords

9 FLUOROETHYL 9 O NORDIHYDROTETRABENAZINE F 18; 9 FLUOROPROPYL 9 O NORDIHYDROTETRABENAZINE F 18; DIHYDROTETRABENAZINE; FLUORINE 18; TETRABENAZINE; TRACER; UNCLASSIFIED DRUG; VESICULAR MONOAMINE TRANSPORTER 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; DEFLUORINATION; DRUG BINDING; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG HALF LIFE; FEMALE; ISOMER; MONKEY; NONHUMAN; RAT;

ANIMALS; BRAIN; FLUORINE RADIOISOTOPES; HAPLORHINI; METABOLIC CLEARANCE RATE; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; TETRABENAZINE; TISSUE DISTRIBUTION; VESICULAR MONOAMINE TRANSPORT PROTEINS;

EID: 33947319832     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2007.01.007     Document Type: Article

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