Correlation of expression levels of BLyS and its receptors with multiple myeloma

Clinical Biochemistry

Volumn 42, Issue 4-5, 2009, Pages 387-399

  Ju, Shaoqing ^a   Wang, Yueguo ^a   Ni, Hongbing ^a   Wang, Xudong ^a   Jiang, Pu ^a   Kong, Xiantao ^b   Zhong, Renqian ^b  

^a NANTONG UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

B lymphocyte stimulator; beta 2 microglobulin; Immunoglobulin; Lactate dehydrogenase; Light chain; Multiple myeloma

Indexed keywords

B CELL ACTIVATING FACTOR; B CELL ACTIVATING FACTOR RECEPTOR; BETA 2 MICROGLOBULIN; BIOLOGICAL MARKER; LACTATE DEHYDROGENASE; MESSENGER RNA; IMMUNOGLOBULIN LIGHT CHAIN;

ADULT; AGED; ARTICLE; CANCER PATIENT; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; MULTIPLE MYELOMA; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; REAL TIME POLYMERASE CHAIN REACTION; CASE CONTROL STUDY; CELL CLONE; ELECTROPHORESIS; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED; MOLECULAR GENETICS; POLYMERASE CHAIN REACTION; REFERENCE VALUE; REPRODUCIBILITY;

ADULT; AGED; B-CELL ACTIVATING FACTOR; B-CELL ACTIVATION FACTOR RECEPTOR; BASE SEQUENCE; BETA 2-MICROGLOBULIN; CASE-CONTROL STUDIES; CLONE CELLS; ELECTROPHORESIS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOGLOBULIN LIGHT CHAINS; L-LACTATE DEHYDROGENASE; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MULTIPLE MYELOMA; POLYMERASE CHAIN REACTION; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER;

EID: 60949097931     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2008.10.024     Document Type: Article

References (32)

1. Moore P.A., Belvedere O., Orr A., et al. BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science 285 (1999) 260-263
2. Schneider P., MacKay F., Steiner V., et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J. Exp. Med. 189 (1999) 1747-1756
3. Mukhopadhyay A., Ni J., Zhai Y., et al. Identification and characterization of a novel cytokine, THANK, a TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase. J. Biol. Chem. 274 (1999) 15978-15981
4. Shu H.B., Hu W.H., and Johnson H. TALL-1 is a novel member of the TNF family that is down-regulated by mitogens. J. Leukoc. Biol. 65 (1999) 680-683
5. Tribouley C., Wallroth M., Chan V., et al. Characterization of a new member of the TNF family expressed on antigen presenting cells. Biol. Chem. 380 (1999) 1443-1447
6. Kawasaki A., Tsuchiya N., Fukazawa T., et al. Presence of four major haplotypes in human BCMA gene: lack of association with systemic lupus erythematosus and rheumatoid arthritis. Genes Immun. 2 (2001) 276-279
7. Gross J.A., Johnston J., Mudri S., et al. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature 404 (2000) 995-999
8. Mackay F., Woodcock S.A., Lawton P., et al. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J. Exp. Med. 190 (1999) 1697-1710
9. Khare S.D., Sarosi I., Xia X.Z., et al. Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 3370-3375
10. Thompson J.S., Schneider P., Kalled S.L., et al. BAFF binds to the tumor necrosis factor receptorlike molecule B cell maturation antigen and is important for maintaining the peripheral B cell population. J. Exp. Med. 192 (2000) 129-135
11. Thompson J.S., Bixler S.A., Qian F., et al. BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science 293 (2001) 2108-2111
12. Yan M., Brady J.R., Chan B., et al. Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency. Curr. Biol. 11 (2001) 1547-1552
13. Hsu B.L., Harless S.M., Hilbert D.M., et al. Cutting edge :BLyS enables survival of transitional and mature B cells through distinct mediators[J ]. J. Immunol. 168 (2002) 5993-5996
14. Batten M., Groom J., Cachero T.G., et al. BAFF mediates survival of peripheral immature B lyphocytes[J ]. J. Exp. Med. 192 (2000) 1453-1465
15. Seshasayee D., Valdez P., Yan M., et al. Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor. Immunity 18 (2003) 279-288
16. Yan M., Wang H., Chan B., et al. Activation and accumulation of B cells in TACI-deficient mice. Nat. Immunol. 2 (2001) 638-643
17. Cheema G.S., Roschke V., Hilbert D.M., et al. Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases. Arthritis Rheum. 44 (2001) 1313-1319
18. Yu G., Boone T., Delaney J., et al. APRIL and TALL-1 and receptor BCMA and TACI: system for regulating humoral immunity. Nat. Immunol. 1 (2000) 252-256
19. Stohl W., Brady J.R., Chan B., et al. Systemic lupus erythematosus: a blissless disease of too much BLyS (B lymphocyte stimulator) protein. Curr. Opin. Rheumatol. 14 (2002) 522-528
20. Stohl W., Metyas S., Tan S.M., et al. B Lymphocyte stimulator overexpression in patients with systemic lupus erythematosus. Arthritis Rheum. 48 (2003) 3475-3486
21. Mariette X., Roux S., Zhang J., et al. The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjögren 's syndrome. Ann. Rheum. Dis. 62 (2003) 168-171
22. Krumbholz M., Theil D., Derfuss T., et al. BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. J. Exp. Med. 201 (2005) 195-200
23. Novak A.J., Darce J.R., Arendt B.K., et al. Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival. Blood 103 (2004) 689-694
24. Briones J., Timmerman J.M., Hilbert D.M., et al. BLyS and BLyS receptor expression in non-Hodgkin's lymphoma. Exp. Hematol. 30 (2002) 135-141
25. Rodriguez B., Valdez H., Freimuth W., et al. Plasma levels of B-lymphocyte stimulator increase with HIV disease progression. AIDS 17 (2003) 1983-1985
26. Scapini P., Nardelli B., Nadali G., et al. G-CSF-stimulated neutrophils are a prominent source of functional BLyS. J. Exp. Med. 197 (2003) 297-302
27. Nardelli B., Belvedere O., Roschke V., et al. Synthesis and release of B-lymphocyte stimulator from myeloid cells. Blood 97 (2001) 198-204
28. Craxton A., Magaletti D., Ryan E.J., et al. Macrophage- and dendritic cell-dependent regulation of human B-cell proliferation requires the TNFfamily ligand BAFF. Blood 101 (2003) 4464-4471
29. O'Connor B.P., Raman V.S., Erickson L.D., et al. BCMA is essential for the survival of long-lived bone marrow plasma cells. J. Exp. Med. 199 1 (2004) 91-98
30. Klein U., Rajewsky K., and Kuppers R. Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells. J. Exp. Med. 188 (1998) 1679-1689
31. Tarte K., De Vos J., Thykjaer T., et al. Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts. Blood 100 (2002) 1113-1122
32. Tarte K., Zhan F., De Vos J., et al. Gene expression profiling of plasma cells and plasmablasts: toward a better understanding of the late stages of B-cell differentiation. Blood 102 (2003) 592-600