Rufinamide for the treatment of epileptic spasms

Epilepsy and Behavior

Volumn 20, Issue 2, 2011, Pages 344-348

  Olson, H E ^a   Loddenkemper, T ^a   Vendrame, M ^a   Poduri, A ^a   Takeoka, M ^a   Bergin, A M ^a   Libenson, M H ^a   Duffy, F H ^a   Rotenberg, A ^a   Coulter, D ^a   Bourgeois, B F ^a   Kothare, S V ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Epilepsy; Epileptic spasms; Rufinamide; West syndrome

Indexed keywords

RUFINAMIDE;

ADL DISABILITY; APPETITE; ARTICLE; BEHAVIOR CHANGE; BLURRED VISION; CHILD; CLINICAL ARTICLE; DEMOGRAPHY; DIZZINESS; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERANCE; DRUG WITHDRAWAL; EPILEPSY; EPILEPTIC SPASM; FALLING; FEMALE; FOLLOW UP; HUMAN; HYPSARRHYTHMIA; MALE; MEDICAL RECORD REVIEW; PRESCHOOL CHILD; PROSPECTIVE STUDY; RASH; SCHOOL CHILD; SEDATION; SEIZURE; SIDE EFFECT; STRABISMUS; TREATMENT DURATION; VOMITING;

ADOLESCENT; ANTICONVULSANTS; CHILD; CHILD, PRESCHOOL; ELECTROENCEPHALOGRAPHY; EPILEPSY; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; MALE; RETROSPECTIVE STUDIES; SPASMS, INFANTILE; TREATMENT OUTCOME; TRIAZOLES; YOUNG ADULT;

EID: 79951669642     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2010.11.023     Document Type: Article

References (31)

1. Berg A.T., Berkovic S.F., Brodie M.J., et al. Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005-2009. Epilepsia 2010, 51:676-685.
2. Camfield P., Camfield C., Lortie A., Darwish H. Infantile spasms in remission may reemerge as intractable epileptic spasms. Epilepsia 2003, 44:1592-1595.
3. Goldstein J., Slomski J. Epileptic spasms: a variety of etiologies and associated syndromes. J Child Neurol 2008, 23:407-414.
4. Talwar D., Baldwin M.A., Hutzler R., Griesemer D.A. Epileptic spasms in older children: persistence beyond infancy. Epilepsia 1995, 36:151-155.
5. Hancock E.C., Osborne J.P., Edwards S.W. Treatment of infantile spasms. Cochrane Database Syst Rev 2008, CD001770.
6. Elterman R.D., Shields W.D., Mansfield K.A., Nakagawa J. Randomized trial of vigabatrin in patients with infantile spasms. Neurology 2001, 57:1416-1421.
7. Elterman R.D., Shields W.D., Bittman R.M., Torri S.A., Sagar S.M., Collins S.D. Vigabatrin for the treatment of infantile spasms: final report of a randomized trial. J Child Neurol 2010, 25:1340-1347.
8. Pellock J.M., Hrachovy R., Shinnar S., et al. Infantile spasms: a U.S. consensus report. Epilepsia 2010, 51:2175-2189.
9. Fois A. Infantile spasms: review of the literature and personal experience. It J Pediatr 2010, 36:15.
10. Hamano S., Yoshinari S., Higurashi N., Tanaka M., Minamitani M., Eto Y. Developmental outcomes of cryptogenic West syndrome. J Pediatr 2007, 150:295-299.
11. Riikonen R. Infantile spasms: therapy and outcome. J Child Neurol 2004, 19:401-404.
12. Riikonen R.S. Favourable prognostic factors with infantile spasms. Eur J Paediatr Neurol 2010, 14:13-18.
13. Brodie M.J., Rosenfeld W.E., Vazquez B., et al. Rufinamide for the adjunctive treatment of partial seizures in adults and adolescents: a randomized placebo-controlled trial. Epilepsia 2009, 50:1899-1909.
14. Cheng-Hakimian A., Anderson G.D., Miller J.W. Rufinamide: pharmacology, clinical trials, and role in clinical practice. Int J Clin Pract 2006, 60:1497-1501.
15. Coppola G., Grosso S., Franzoni E., et al. Rufinamide in refractory childhood epileptic encephalopathies other than Lennox-Gastaut syndrome. Eur J Neurol 2010, 10.1111/j.1468-1331.2010.03113.x.
16. Elger C.E., Stefan H., Mann A., Narurkar M., Sun Y., Perdomo C. A 24-week multicenter, randomized, double-blind, parallel-group, dose-ranging study of rufinamide in adults and adolescents with inadequately controlled partial seizures. Epilepsy Res 2010, 88:255-263.
17. Glauser T., Kluger G., Sachdeo R., Krauss G., Perdomo C., Arroyo S. Rufinamide for generalized seizures associated with Lennox-Gastaut syndrome. Neurology 2008, 70:1950-1958.
18. Kluger G., Glauser T., Krauss G., Seeruthun R., Perdomo C., Arroyo S. Adjunctive rufinamide in Lennox-Gastaut syndrome: a long-term, open-label extension study. Acta Neurol Scand 2010, 122:202-208.
19. Kluger G., Haberlandt E., Kurlemann G., et al. First European long-term experience with the orphan drug rufinamide in childhood-onset refractory epilepsy. Epilepsy Behav 2010, 17:546-548.
20. Kluger G., Kurlemann G., Haberlandt E., et al. Effectiveness and tolerability of rufinamide in children and adults with refractory epilepsy: first European experience. Epilepsy Behav 2009, 14:491-495.
21. Palhagen S., Canger R., Henriksen O., van Parys J.A., Riviere M.E., Karolchyk M.A. Rufinamide: a double-blind, placebo-controlled proof of principle trial in patients with epilepsy. Epilepsy Res 2001, 43:115-124.
22. Wheless J.W., Conry J., Krauss G., Mann A., LoPresti A., Narurkar M. Safety and tolerability of rufinamide in children with epilepsy: a pooled analysis of 7 clinical studies. J Child Neurol 2009, 24:1520-1525.
23. Wisniewski C.S. Rufinamide: a new antiepileptic medication for the treatment of seizures associated with Lennox-Gastaut syndrome. Ann Pharmacother 2010, 44:658-667.
24. Perucca E., Cloyd J., Critchley D., Fuseau E. Rufinamide: clinical pharmacokinetics and concentration-response relationships in patients with epilepsy. Epilepsia 2008, 49:1123-1141.
25. Wheless J.W., Vazquez B. Rufinamide: a novel broad-spectrum antiepileptic drug. Epilepsy Curr 2010, 10:1-6.
26. Vendrame M., Loddenkemper T., Gooty V.D., et al. Experience with rufinamide in a pediatric population: a single center's experience. Pediatr Neurol 2010, 43:155-158.
27. Blume W.T., Luders H.O., Mizrahi E., Tassinari C. van Emde Boas W, Engel J Jr. Glossary of descriptive terminology for ictal semiology: report of the ILAE task force on classification and terminology. Epilepsia 2001, 42:1212-1218.
28. Jeavons P. West syndrome: infantile spasms. Epileptic syndromes in infancy, childhood and adolescence 1985, 42-50. John Libbey Eurotext. J. Roger, C. Dravet, M. Bureau, F.E. Dreifuss, P. Wolf (Eds.).
29. Egli M., Mothersill I., O'Kane M., O'Kane F. The axial spasm-the predominant type of drop seizure in patients with secondary generalized epilepsy. Epilepsia 1985, 26:401-415.
30. Ikeno T., Shigematsu H., Miyakoshi M., Ohba A., Yagi K., Seino M. An analytic study of epileptic falls. Epilepsia 1985, 26:612-621.
31. Arroyo S. Rufinamide. Neurotherapeutics 2007, 4:155-162.