메뉴 건너뛰기




Volumn 60, Issue 11, 2006, Pages 1497-1501

Rufinamide: Pharmacology, clinical trials, and role in clinical practice

Author keywords

Anti epileptic drugs; Epilepsy; Lennox Gastautsyndrome; Localisation related epilepsy; Rufinamide; Seizures

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; CLOBAZAM; CLONAZEPAM; CPG 33101; CYTOCHROME P450; FELBAMATE; LAMOTRIGINE; ORAL CONTRACEPTIVE AGENT; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PLACEBO; PRIMIDONE; RUFINAMIDE; SODIUM ION; TOPIRAMATE; UNCLASSIFIED DRUG; VALPROIC ACID; VIGABATRIN;

EID: 33749818806     PISSN: 13685031     EISSN: 17421241     Source Type: Journal    
DOI: 10.1111/j.1742-1241.2006.01173.x     Document Type: Article
Times cited : (52)

References (22)
  • 1
    • 0025031682 scopus 로고
    • Seizure recurrence after a first unprovoked seizure; an extended follow-up
    • Hauser WA, Rich SS, Annegers JF, Anderson VE. Seizure recurrence after a first unprovoked seizure; an extended follow-up. Neurology 1990; 400: 1163-70.
    • (1990) Neurology , vol.400 , pp. 1163-1170
    • Hauser, W.A.1    Rich, S.S.2    Annegers, J.F.3    Anderson, V.E.4
  • 2
    • 0034598762 scopus 로고    scopus 로고
    • Early identification of refractory epilepsy
    • Kwan P, Brodie M. Early identification of refractory epilepsy. N Engl J Med 2000; 342: 31-9.
    • (2000) N Engl J Med , vol.342 , pp. 31-39
    • Kwan, P.1    Brodie, M.2
  • 3
    • 25444491571 scopus 로고    scopus 로고
    • Predicting long-term seizure outcome after resective epilepsy surgery; the multicenter study
    • Spencer SS, Berg AT, Vickrey BG et.al. Predicting long-term seizure outcome after resective epilepsy surgery; the multicenter study. Neurology 2005; 65: 912-8.
    • (2005) Neurology , vol.65 , pp. 912-918
    • Spencer, S.S.1    Berg, A.T.2    Vickrey, B.G.3
  • 4
    • 20444398782 scopus 로고    scopus 로고
    • Prognosis 30years after temporal lobectomy
    • Kelley K, Theodore W. Prognosis 30years after temporal lobectomy. Neurology 2005; 64: 1974-6.
    • (2005) Neurology , vol.64 , pp. 1974-1976
    • Kelley, K.1    Theodore, W.2
  • 6
    • 0031959729 scopus 로고    scopus 로고
    • The influence of food on the disposition of the antiepileptic drug rufinamide in healthy volunteers
    • Cardot JM, Lecaillon JB, Czendlik C, Godbillon J. The influence of food on the disposition of the antiepileptic drug rufinamide in healthy volunteers. Biopharm Drug Dispos 1998; 19: 259-62.
    • (1998) Biopharm Drug Dispos , vol.19 , pp. 259-262
    • Cardot, J.M.1    Lecaillon, J.B.2    Czendlik, C.3    Godbillon, J.4
  • 7
    • 0029566317 scopus 로고
    • Intra- and inter-subject variabilities of CGP 33101 after replicate single oral doses of two 200mg tablets and 400mg suspension
    • Cheung WK, Kianifard F, Wong A et al. Intra- and inter-subject variabilities of CGP 33101 after replicate single oral doses of two 200mg tablets and 400mg suspension. Pharm Res 1995; 12: 1878-82.
    • (1995) Pharm Res , vol.12 , pp. 1878-1882
    • Cheung, W.K.1    Kianifard, F.2    Wong, A.3
  • 8
    • 0000029301 scopus 로고    scopus 로고
    • Metabolism of the new anticonvulsant trial drug rufinamide (CGP33101) in healthy male volunteers
    • Waldmeier F. Metabolism of the new anticonvulsant trial drug rufinamide (CGP33101) in healthy male volunteers. Epilepsia 1996; 37 (Suppl. 5): 167.
    • (1996) Epilepsia , vol.37 , Issue.SUPPL. 5 , pp. 167
    • Waldmeier, F.1
  • 9
    • 0006757668 scopus 로고    scopus 로고
    • A pharmacokinetic evaluation of rufinamide in elderly and younger subjects
    • Chang S-W, Choi L, Karolchyk MA. A pharmacokinetic evaluation of rufinamide in elderly and younger subjects. Epilepsia 1998; 39 (Suppl. 6): 59.
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 6 , pp. 59
    • Chang, S.-W.1    Choi, L.2    Karolchyk, M.A.3
  • 10
    • 0000489497 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of adjunctive rufinamide therapy in pediatric patients with epilepsy
    • Sachdeo RC, Rosenfeld WE, Choi L, Yeh C-M, Cooper AN, Karolchyk MA. Pharmacokinetics and safety of adjunctive rufinamide therapy in pediatric patients with epilepsy. Epilepsia 1998; 39 (Suppl. 6): 166-7.
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 6 , pp. 166-167
    • Sachdeo, R.C.1    Rosenfeld, W.E.2    Choi, L.3    Yeh, C.-M.4    Cooper, A.N.5    Karolchyk, M.A.6
  • 12
    • 32744471584 scopus 로고    scopus 로고
    • Efficacy and safety of rufinamide as adjunctive therapy in adult patients with therapy resistant partial onset seizures
    • Vasquez B. Efficacy and safety of rufinamide as adjunctive therapy in adult patients with therapy resistant partial onset seizures. Epilepsia 2000; 41 (Suppl. 7): 255.
    • (2000) Epilepsia , vol.41 , Issue.SUPPL. 7 , pp. 255
    • Vasquez, B.1
  • 15
    • 0006490626 scopus 로고    scopus 로고
    • Safety and Efficacy of open label rufinamide as adjunctive therapy in pediatric patients with partial seizures
    • Litzinger M. Safety and Efficacy of open label rufinamide as adjunctive therapy in pediatric patients with partial seizures. Epilepsia 1999; 40 (Suppl. 7): 114.
    • (1999) Epilepsia , vol.40 , Issue.SUPPL. 7 , pp. 114
    • Litzinger, M.1
  • 16
    • 33749829255 scopus 로고    scopus 로고
    • The Effect of Rufinamide on the QT Interval in Healthy Subjects Treated During 18days with Multiple Ascending Doses: A Population PKPD Analysis
    • Abstract 785 of the
    • Marchand M, Critchley D, Nagy C et al. The Effect of Rufinamide on the QT Interval in Healthy Subjects Treated During 18days with Multiple Ascending Doses: A Population PKPD Analysis. Abstract 785 of the Annual Meeting of the Population Approach Group in Europe, 2005.
    • (2005) Annual Meeting of the Population Approach Group in Europe
    • Marchand, M.1    Critchley, D.2    Nagy, C.3
  • 17
    • 33746111455 scopus 로고    scopus 로고
    • The effect of the new antiepileptic drug rufinamide on cognitive functions
    • Aldenkamp A, Alpherts W. The effect of the new antiepileptic drug rufinamide on cognitive functions. Epilepsia 2006; 47: 1153-9.
    • (2006) Epilepsia , vol.47 , pp. 1153-1159
    • Aldenkamp, A.1    Alpherts, W.2
  • 18
    • 0034642350 scopus 로고    scopus 로고
    • Clinical pharmacology of new antiepileptic drugs
    • Willmore J. Clinical pharmacology of new antiepileptic drugs. Neurology 2000; 55 (11 Suppl. 3): 17-34.
    • (2000) Neurology , vol.55 , Issue.11 SUPPL. 3 , pp. 17-34
    • Willmore, J.1
  • 19
    • 0006492632 scopus 로고    scopus 로고
    • Single-center, open-label, multiple dose pharmacokinetic trial investigating the effect of rufinamide administration on Ortho-Novum 1/ 35 in healthy women
    • Svendsen KD, Choid L, Chen B-L. Single-center, open-label, multiple dose pharmacokinetic trial investigating the effect of rufinamide administration on Ortho-Novum 1/35 in healthy women. Epilepsia 1998; 39 (Suppl. 6): 59.
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 6 , pp. 59
    • Svendsen, K.D.1    Choid, L.2    Chen, B.-L.3
  • 20
    • 0031453973 scopus 로고    scopus 로고
    • Lamotrigine for generalized seizures associated with the Lennox-Gastaut Syndrome
    • Motte J, Trevathan E, Arvidsson JF et al. Lamotrigine for generalized seizures associated with the Lennox-Gastaut Syndrome. N Engl J Med 1997; 337: 1807-12.
    • (1997) N Engl J Med , vol.337 , pp. 1807-1812
    • Motte, J.1    Trevathan, E.2    Arvidsson, J.F.3
  • 21
    • 0032976081 scopus 로고    scopus 로고
    • A double-blind, randomized trial of topiramate in Lennox-Gastaut Syndrome: Topiramate YL Study Group
    • Sachdeo R, Glauser T, Ritter F et al. A double-blind, randomized trial of topiramate in Lennox-Gastaut Syndrome: Topiramate YL Study Group. Neurology 1999; 52: 1882-7.
    • (1999) Neurology , vol.52 , pp. 1882-1887
    • Sachdeo, R.1    Glauser, T.2    Ritter, F.3
  • 22
    • 0027530628 scopus 로고
    • Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut Syndrome)
    • The Felbamate Study Group in Lennox-Gastaut Syndrome
    • The Felbamate Study Group in Lennox-Gastaut Syndrome. Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut Syndrome). N Engl J Med 1993; 1328: 29-33.
    • (1993) N Engl J Med , vol.1328 , pp. 29-33


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.