Pathway-selective suppression of chemokine receptor signaling in B cells by LPS through downregulation of PLC-β2

Cellular and Molecular Immunology

Volumn 7, Issue 6, 2010, Pages 428-439

  Shirakawa, Aiko Konno ^a   Liao, Fang ^a   Zhang, Hongwei H ^a   Hedrick, Michael N ^a   Singh, Satya P ^a   Wu, Dianqing ^b   Farber, Joshua M ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

B cells; calcium; chemokine; chemotaxis; GPCR

Indexed keywords

CALCIUM ION; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CCR7; CYCLIC AMP DEPENDENT PROTEIN KINASE; IMMUNOGLOBULIN M ANTIBODY; LIPOPOLYSACCHARIDE; MESSENGER RNA; PHOSPHOLIPASE C BETA2;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE ACTIVATION; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL ISOLATION; CHEMOTAXIS; CONTROLLED STUDY; DOWN REGULATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; IMMUNOREGULATION; INTRACELLULAR SIGNALING; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; QUANTITATIVE ANALYSIS; SPLEEN CELL; WESTERN BLOTTING;

ANIMALS; B-LYMPHOCYTES; CALCIUM; CALCIUM SIGNALING; CHEMOKINES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; IMMUNOGLOBULIN M; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MICE; MODELS, IMMUNOLOGICAL; PHOSPHOLIPASE C BETA; RECEPTORS, CHEMOKINE; RNA, MESSENGER; SIGNAL TRANSDUCTION; TYPE C PHOSPHOLIPASES;

MUS;

EID: 79951655546     PISSN: 16727681     EISSN: None     Source Type: Journal    
DOI: 10.1038/cmi.2010.46     Document Type: Article

References (53)

1. Nagasawa T, Hirota S, Tachibana K, Takakura N, Nishikawa S, Kitamura Y et al. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature 1996;382:635-638. (Pubitemid 26268957)
2. Hargreaves DC, Hyman PL, Lu TT, Ngo VN, Bidgol A, Suzuki G et al. A coordinated change in chemokine responsiveness guides plasma cell movements. J Exp Med 2001;194:45-56. (Pubitemid 32660436)
3. Allen CD, Ansel KM, Low C, Lesley R, Tamamura H, Fujii N et al. Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5. Nat Immunol 2004;5:943-952. (Pubitemid 39276239)
4. Forster R, Mattis AE, Kremmer E, Wolf E, Brem G, Lipp M. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 1996;87:1037-1047. (Pubitemid 26427987)
5. Reif K, Ekland EH, Ohl L, Nakano H, Lipp M, Forster R et al. Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position. Nature 2002;416:94-99. (Pubitemid 34215407)
6. Cook DN, Prosser DM, Forster R, Zhang J, Kuklin NA, Abbondanzo SJ et al. CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue. Immunity 2000;12:495-503.
7. Kunkel EJ, Kim CH, Lazarus NH, Vierra MA, Soler D, Bowman EP et al. CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Absecreting cells. J Clin Invest 2003;111:1001-1010. (Pubitemid 36397476)
8. Hieshima K, Kawasaki Y, Hanamoto H, Nakayama T, Nagakubo D, Kanamaru A et al. CC chemokine ligands 25 and 28 play essential roles in intestinal extravasation of IgA antibody-secreting cells. J Immunol 2004;173:3668-3675. (Pubitemid 39280727)
9. Wilson E, Butcher EC. CCL28 controls immunoglobulin (Ig) A plasma cell accumulation in the lactating mammary gland and IgA antibody transfer to the neonate. J Exp Med 2004;200:805-809. (Pubitemid 39299466)
10. Park MK, Amichay D, Love P, Wick E, Liao F, Grinberg A et al. The CXC chemokine murine monokine induced by IFN-gamma (CXC chemokine ligand 9) is made by APCs, targets lymphocytes including activated B cells, and supports antibody responses to a bacterial pathogen in vivo. J Immunol 2002;169:1433-1443. (Pubitemid 34811943)
11. Hauser AE, Debes GF, Arce S, Cassese G, Hamann A, Radbruch A et al. Chemotactic responsiveness toward ligands for CXCR3 and CXCR4 is regulated on plasma blasts during the time course of a memory immune response. J Immunol 2002;169:1277-1282. (Pubitemid 34809169)
12. Honczarenko M, Douglas RS, Mathias C, Lee B, Ratajczak MZ, Silberstein LE. SDF-1 responsiveness does not correlate with CXCR4 expression levels of developing human bone marrow B cells. Blood 1999;94:2990-2998. (Pubitemid 29512702)
13. Brandes M, Legler DF, Spoerri B, Schaerli P, Moser B. Activation-dependent modulation of B lymphocyte migration to chemokines. Int Immunol 2000;12:1285-1292. (Pubitemid 30657772)
14. Liao F, Shirakawa AK, Foley JF, Rabin RL, Farber JM. Human B cells become highly responsive to macrophage-inflammatory protein-3 alpha/CC chemokine ligand-20 after cellular activation without changes in CCR6 expression or ligand binding. J Immunol 2002;168:4871-4880. (Pubitemid 34495948)
15. Casamayor-Palleja M, Mondiere P, Verschelde C, Bella C, Defrance T. BCR ligation reprograms B cells for migration to the T zone and B-cell follicle sequentially. Blood 2002;99:1913-1921. (Pubitemid 34525469)
16. Badr G, Borhis G, Treton D, Richard Y. IFN{alpha} enhances human B-cell chemotaxis by modulating ligand-induced chemokine receptor signaling and internalization. Int Immunol 2005;17:459-467. (Pubitemid 40568121)
17. Kehrl JH. Chemoattractant receptor signaling and the control of lymphocyte migration. Immunol Res 2006;34:211-227. (Pubitemid 44195937)
18. Stephens L, Milne L, Hawkins P. Moving towards a better understanding of chemotaxis. Curr Biol 2008;18: R485-494. (Pubitemid 351734644)
19. Bach TL, Chen QM, Kerr WT, Wang Y, Lian L, Choi JK et al. Phospholipase cbeta is critical for T cell chemotaxis. J Immunol 2007;179:2223-2227.
20. Rhee SG. Regulation of phosphoinositide-specific phospholipase C. Annu Rev Biochem 2001;70:281-312. (Pubitemid 32662212)
21. Park D, Jhon DY, Kriz R, Knopf J, Rhee SG. Cloning, sequencing, expression, and Gqindependent activation of phospholipase C-beta 2. J Biol Chem 1992;267:16048-16055.
22. Jiang H, Kuang Y, Wu Y, Xie W, Simon MI, Wu D. Roles of phospholipase C beta2 in chemoattractant-elicited responses. Proc Natl Acad Sci USA 1997;94:7971-7975. (Pubitemid 27343759)
23. 2+-and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils. Nature 1995;377:75-79.
24. Katagiri K, Ohnishi N, Kabashima K, Iyoda T, Takeda N, Shinkai Y et al. Crucial functions of the Rap1 effector molecule RAPL in lymphocyte and dendritic cell trafficking. Nat Immunol 2004;5:1045-1051. (Pubitemid 41057724)
25. McLeod SJ, Li AH, Lee RL, Burgess AE, Gold MR. The Rap GTPases regulate B cell migration toward the chemokine stromal cell-derived factor-1 (CXCL12): potential role for Rap2 in promoting B cell migration. J Immunol 2002;169:1365-1371. (Pubitemid 34809180)
26. Bergmeier W, Goerge T, Wang HW, Crittenden JR, Baldwin AC, Cifuni SM et al. Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III. J Clin Invest 2007;117:1699-1707. (Pubitemid 46871354)
27. Liao F, Rabin RL, Yannelli JR, Koniaris LG, Vanguri P, Farber JM. Human Mig chemokine: biochemical and functional characterization. J Exp Med 1995;182:1301-1314.
28. Amichay D, Gazzinelli RT, Karupiah G, Moench TR, Sher A, Farber JM. Genes for chemokines MuMig and Crg-2 are induced in protozoan and viral infections in response to IFN-gamma with patterns of tissue expression that suggest nonredundant roles in vivo. J Immunol 1996;157:4511-4520. (Pubitemid 126449372)
29. Heesen M, Berman MA, Benson JD, Gerard C, Dorf ME. Cloning of the mouse fusin gene, homologue to a human HIV-1 co-factor. J Immunol 1996;157:5455-5460. (Pubitemid 126448965)
30. Ali H, Fisher I, Haribabu B, Richardson RM, Snyderman R. Role of phospholipase Cbeta3 phosphorylation in the desensitization of cellular responses to plateletactivating factor. J Biol Chem 1997;272:11706-11709. (Pubitemid 27202733)
31. Liu M, Simon MI. Regulation by cAMP-dependent protein kinease of a G-proteinmediated phospholipase C. Nature 1996;382:83-87. (Pubitemid 26243363)
32. Park DJ, Min HK, Rhee SG. Inhibition of CD3-linked phospholipase C by phorbol ester and by cAMP is associated with decreased phosphotyrosine and increased phosphoserine contents of PLC-gamma 1. J Biol Chem 1992;267:1496-1501.
33. Li Z, Jiang H, Xie W, Zhang Z, Smrcka AV, Wu D. Roles of PLC-beta2 and-beta3 and PI3Kgamma in chemoattractant-mediated signal transduction. Science 2000;287:1046-1049. (Pubitemid 30094361)
34. Pettit EJ, Fay FS. Cytosolic free calcium and the cytoskeleton in the control of leukocyte chemotaxis. Physiol Rev 1998;78:949-967. (Pubitemid 28491946)
35. Wei C, Wang X, Chen M, Ouyang K, Song LS, Cheng H. Calcium flickers steer cell migration. Nature 2009;457:901-905.
36. Reedquist KA, Bos JL. Costimulation through CD28 suppresses T cell receptordependent activation of the Ras-like small GTPase Rap1 in human T lymphocytes. J Biol Chem 1998;273:4944-4949. (Pubitemid 28108647)
37. Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G et al. Cell migration: integrating signals from front to back. Science 2003;302:1704-1709. (Pubitemid 37505725)
38. Colvin RA, Means TK, Diefenbach TJ, Moita LF, Friday RP, Sever S et al. Synaptotagminmediated vesicle fusion regulates cell migration. Nat Immunol 2010;11:495-502.
39. Cronshaw DG, Kouroumalis A, Parry R, Webb A, Brown Z, Ward SG. Evidence that phospholipase-C-dependent, calcium-independent mechanisms are required for directional migration of T-lymphocytes in response to the CCR4 ligands CCL17 and CCL22. J Leukoc Biol 2006;79:1369-1380. (Pubitemid 44835572)
40. Crittenden JR, Bergmeier W, Zhang Y, Piffath CL, Liang Y, Wagner DD et al. CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation. Nat Med 2004;10:982-986. (Pubitemid 39273740)
41. Siliceo M, Garcia-Bernal D, Carrasco S, Diaz-Flores E, Coluccio Leskow F, Teixido J et al. Beta2-chimaerin provides a diacylglycerol-dependent mechanism for regulation of adhesion and chemotaxis of T cells. J Cell Sci 2006;119:141-152. (Pubitemid 43169307)
42. Pasvolsky R, Grabovsky V, Giagulli C, Shulman Z, Shamri R, Feigelson SW et al. RhoA is involved in LFA-1 extension triggered by CXCL12 but not in a novel outside-in LFA-1 activation facilitated by CXCL9. J Immunol 2008;180:2815-2823.
43. Bertagnolo V, Marchisio M, Pierpaoli S, Colamussi ML, Brugnoli F, Visani G et al. Selective up-regulation of phospholipase C-beta2 during granulocytic differentiation of normal and leukemic hematopoietic progenitors. J Leukoc Biol 2002;71:957-965.
44. Schnabel P, Mies F, Nohr T, Geisler M, Bohm M. Differential regulation of phospholipase C-beta isozymes in cardiomyocyte hypertrophy. Biochem Biophys Res Commun 2000;275:1-6. (Pubitemid 30663619)
45. Asemu G, Tappia PS, Dhalla NS. Identification of the changes in phospholipase C isozymes in ischemic-reperfused rat heart. Arch Biochem Biophys 2003;411:174-182. (Pubitemid 36298644)
46. Dwivedi Y, Pandey GN. Repeated administration of dexamethasone increases phosphoinositide-specific phospholipase C activity and mRNA and protein expression of the phospholipase C beta 1 isozyme in rat brain. J Neurochem 1999;73:780-790. (Pubitemid 29339853)
47. Cueille C, Frayon S, de Vernejoul MC, Garel JM. Dexamethasone decreases phospholipase C beta1 isozyme expression in human vascular smooth muscle cells. J Steroid Biochem Mol Biol 2003;86:173-178. (Pubitemid 37243994)
48. Grinberg S, Hasko G, Wu D, Leibovich SJ. Suppression of PLCbeta2 by endotoxin plays a role in the adenosine A (2A) receptor-mediated switch of macrophages from an inflammatory to an angiogenic phenotype. Am J Pathol 2009;175:2439-2453.
49. Lee SB, Rao AK, Lee KH, Yang X, Bae YS, Rhee SG. Decreased expression of phospholipase C-beta 2 isozyme in human platelets with impaired function. Blood 1996;88:1684-1691. (Pubitemid 26307063)
50. Okada T, Miller MJ, Parker I, Krummel MF, Neighbors M, Hartley SB et al. Antigenengaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells. PLoS Biol 2005;3: e150.
51. Lu TT, Cyster JG. Integrin-mediated long-term B cell retention in the splenic marginal zone. Science 2002;297:409-412. (Pubitemid 34790772)
52. Sambrano GR, Chandy G, Choi S, Decamp D, Hsueh R, Lin KM et al. Unravelling the signal-transduction network in B lymphocytes. Nature 2002;420:708-710.
53. Feske S. Calcium signalling in lymphocyte activation and disease. Nat Rev Immunol 2007;7:690-702. (Pubitemid 47327393)