메뉴 건너뛰기




Volumn 73, Issue 2, 1999, Pages 780-790

Repeated administration of dexamethasone increases phosphoinositide- specific phospholipase C activity and mRNA and protein expression of the phospholipase C β1 isozyme in rat brain

Author keywords

Dexamethasone; Glucocorticoids; Hypothalamic pituitary adrenal axis; Immunolabeling; Phospholipase C; Rat brain

Indexed keywords

DEXAMETHASONE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHODIESTERASE; PHOSPHOLIPASE C;

EID: 0032788139     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0730780.x     Document Type: Article
Times cited : (21)

References (67)
  • 1
    • 0022900086 scopus 로고
    • Calcium-mobilizing receptors, polyphosphoinosiddes, and the generation of second messengers
    • Abdel-Latif A. A. (1986) Calcium-mobilizing receptors, polyphosphoinosiddes, and the generation of second messengers. Pharmacol. Rev. 38, 227-271.
    • (1986) Pharmacol. Rev. , vol.38 , pp. 227-271
    • Abdel-Latif, A.A.1
  • 2
    • 0025681492 scopus 로고
    • Binding of SH2 domains of phospholipase C1, GAP, and Src to activated growth factor receptors
    • Anderson D., Koch C. A., Grey L., Ellis C., Moran M. F., and Pawson T. (1990) Binding of SH2 domains of phospholipase C1, GAP, and Src to activated growth factor receptors. Science 250, 979-982.
    • (1990) Science , vol.250 , pp. 979-982
    • Anderson, D.1    Koch, C.A.2    Grey, L.3    Ellis, C.4    Moran, M.F.5    Pawson, T.6
  • 3
    • 0023201391 scopus 로고
    • Characterization of partially purified phospholipase C from human platelet membranes
    • Banno Y. and Nozawa Y. (1987) Characterization of partially purified phospholipase C from human platelet membranes. Biochem. J. 248, 95-101.
    • (1987) Biochem. J. , vol.248 , pp. 95-101
    • Banno, Y.1    Nozawa, Y.2
  • 4
    • 0023792637 scopus 로고
    • Purification and characterization of membrane-bound phospholipase C specific for phosphoinositides from human platelets
    • Banno Y., Yada Y., and Nozawa Y. (1988) Purification and characterization of membrane-bound phospholipase C specific for phosphoinositides from human platelets. J. Biol. Chem. 263, 11459-11465.
    • (1988) J. Biol. Chem. , vol.263 , pp. 11459-11465
    • Banno, Y.1    Yada, Y.2    Nozawa, Y.3
  • 5
    • 0027397544 scopus 로고
    • Inositol trisphosphate and calcium signaling
    • Berridge M. J. (1993) Inositol trisphosphate and calcium signaling. Nature 361, 315-325.
    • (1993) Nature , vol.361 , pp. 315-325
    • Berridge, M.J.1
  • 6
    • 0024453294 scopus 로고
    • Inositol phosphates and cell signaling
    • Berridge M. J. and Irvine R. F. (1989) Inositol phosphates and cell signaling. Nature 341, 197-205.
    • (1989) Nature , vol.341 , pp. 197-205
    • Berridge, M.J.1    Irvine, R.F.2
  • 7
    • 0027452182 scopus 로고
    • Dexamethasone target sites in the central nervous system and their potential relevance to mental illness
    • Birmingham M. K., Sar M., and Stumpf W. E. (1993) Dexamethasone target sites in the central nervous system and their potential relevance to mental illness. Cell. Mol. Neurobiol 4, 373-386.
    • (1993) Cell. Mol. Neurobiol , vol.4 , pp. 373-386
    • Birmingham, M.K.1    Sar, M.2    Stumpf, W.E.3
  • 9
    • 0029075361 scopus 로고
    • Regulation of 5HT receptors by corticosteroids: Where do we stand?
    • Chauloff F. (1995) Regulation of 5HT receptors by corticosteroids: where do we stand? Fundam. Clin. Pharmacol. 9, 219-233.
    • (1995) Fundam. Clin. Pharmacol. , vol.9 , pp. 219-233
    • Chauloff, F.1
  • 10
    • 0026468420 scopus 로고
    • Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors
    • Cockcroft S. and Thomas G. M. H. (1992) Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors. Biochem. J. 288, 1-14.
    • (1992) Biochem. J. , vol.288 , pp. 1-14
    • Cockcroft, S.1    Thomas, G.M.H.2
  • 11
    • 0029147429 scopus 로고
    • The protein kinase C and protein kinase C related gene families
    • Dekker L. V., Palmer R. H., and Parker P. J. (1995) The protein kinase C and protein kinase C related gene families. Curr. Opin. Struct. biol. 5, 396-402.
    • (1995) Curr. Opin. Struct. Biol. , vol.5 , pp. 396-402
    • Dekker, L.V.1    Palmer, R.H.2    Parker, P.J.3
  • 12
    • 0016606568 scopus 로고
    • Differences in corticosterone and dexamethasone binding to rat brain and pituitary
    • De Kloet R., Wallach G., and McEwen B. S. (1975) Differences in corticosterone and dexamethasone binding to rat brain and pituitary. Endocrinology 3, 598-609.
    • (1975) Endocrinology , vol.3 , pp. 598-609
    • De Kloet, R.1    Wallach, G.2    McEwen, B.S.3
  • 13
    • 0024575040 scopus 로고
    • Glucocorticoid administration increases receptor-mediated and forskolin-stimulated cyclic AMP accumulation in rat brain cerebral cortical slices
    • Duman R. S., Strada S. J., and Enna S. J. (1989) Glucocorticoid administration increases receptor-mediated and forskolin-stimulated cyclic AMP accumulation in rat brain cerebral cortical slices. Brain Res. 477, 166-171.
    • (1989) Brain Res. , vol.477 , pp. 166-171
    • Duman, R.S.1    Strada, S.J.2    Enna, S.J.3
  • 14
    • 84950650672 scopus 로고
    • Pairwise multiple comparisons in the homogeneous variance: Unequal sample size case
    • Dunnett C. W. (1980) Pairwise multiple comparisons in the homogeneous variance: unequal sample size case. J. Am. Stat. Assoc. 75, 789-795.
    • (1980) J. Am. Stat. Assoc. , vol.75 , pp. 789-795
    • Dunnett, C.W.1
  • 15
    • 0345259000 scopus 로고    scopus 로고
    • 3H]phorbol dibutyrate binding and expression of protein kinase C isozymes in the rat cortex
    • 3H]phorbol dibutyrate binding and expression of protein kinase C isozymes in the rat cortex. Soc. Neurosci. Abstr. 22, 371.
    • (1996) Soc. Neurosci. Abstr. , vol.22 , pp. 371
    • Dwivedi, Y.1    Pandey, G.N.2
  • 16
    • 0030666416 scopus 로고    scopus 로고
    • Effects of subchronic administration of antidepressants and anxiolytics on levels of the α subunits of G proteins in the rat brain
    • Dwivedi Y. and Pandey G. N. (1997) Effects of subchronic administration of antidepressants and anxiolytics on levels of the α subunits of G proteins in the rat brain. J. Neural Transm. 104, 747-760.
    • (1997) J. Neural Transm. , vol.104 , pp. 747-760
    • Dwivedi, Y.1    Pandey, G.N.2
  • 17
    • 0032217042 scopus 로고    scopus 로고
    • 2A receptor mRNA in human postmortem brain using competitive RT-PCR
    • 2A receptor mRNA in human postmortem brain using competitive RT-PCR. Neuroreport 9, 3761-3765.
    • (1998) Neuroreport , vol.9 , pp. 3761-3765
    • Dwivedi, Y.1    Pandey, G.N.2
  • 18
    • 0032924793 scopus 로고    scopus 로고
    • Administration of dexamethasone up-regulates protein kinase C activity and the expression of γ and ∈ protein kinase C isozymes in the rat brain
    • Dwivedi Y. and Pandey G. N. (1999) Administration of dexamethasone up-regulates protein kinase C activity and the expression of γ and ∈ protein kinase C isozymes in the rat brain. J. Neurochem. 72, 380-387.
    • (1999) J. Neurochem. , vol.72 , pp. 380-387
    • Dwivedi, Y.1    Pandey, G.N.2
  • 19
    • 0031594901 scopus 로고    scopus 로고
    • 3H]-inositol 1,4,5-trisphosphate binding sites and expressed inositol 1,4,5-trisphosphate receptor protein level in platelets of depressed patients
    • 3H]-inositol 1,4,5-trisphosphate binding sites and expressed inositol 1,4,5-trisphosphate receptor protein level in platelets of depressed patients. Psychopharmacology 138, 47-54.
    • (1998) Psychopharmacology , vol.138 , pp. 47-54
    • Dwivedi, Y.1    Janicak, P.G.2    Pandey, G.N.3
  • 21
    • 0025217934 scopus 로고
    • Protein - Protein contacts in the glucocorticoid receptor homodimer influence its DNA binding properties
    • Eriksson P. and Wrange O. (1990) Protein - protein contacts in the glucocorticoid receptor homodimer influence its DNA binding properties. J. Biol. Chem. 265, 3535-3542.
    • (1990) J. Biol. Chem. , vol.265 , pp. 3535-3542
    • Eriksson, P.1    Wrange, O.2
  • 22
    • 0028208759 scopus 로고
    • Phosphoinositide phospholipases and G proteins in hormone action
    • Exton J. H. (1994) Phosphoinositide phospholipases and G proteins in hormone action. Annu. Rev. Physiol. 56, 349-369.
    • (1994) Annu. Rev. Physiol. , vol.56 , pp. 349-369
    • Exton, J.H.1
  • 23
    • 0030613808 scopus 로고    scopus 로고
    • 2A receptor binding after chronic corticosterone associated with a behavioral indication of depression but not anxiety
    • 2A receptor binding after chronic corticosterone associated with a behavioral indication of depression but not anxiety. Psychoneuroendocrinology 22, 477-491.
    • (1997) Psychoneuroendocrinology , vol.22 , pp. 477-491
    • Fernandas, C.1    McKittrick, C.R.2    File, S.E.3    McEwen, B.S.4
  • 24
    • 0022379179 scopus 로고
    • Mapping of glucocorticoid receptor immunoreactive neurons in the rat tel- and diencephalon using a monoclonal antibody against rat liver glucocorticoid receptors
    • Fuxe K., Wikstrom A. C., Okret S., Agnati L. F., Harfstrand A., Yu Z Y., Granhol L., Zoli M., Vale W., and Gustafsson J. J. (1985) Mapping of glucocorticoid receptor immunoreactive neurons in the rat tel- and diencephalon using a monoclonal antibody against rat liver glucocorticoid receptors. Endocrinology 117, 1803-1812.
    • (1985) Endocrinology , vol.117 , pp. 1803-1812
    • Fuxe, K.1    Wikstrom, A.C.2    Okret, S.3    Agnati, L.F.4    Harfstrand, A.5    Yu, Z.Y.6    Granhol, L.7    Zoli, M.8    Vale, W.9    Gustafsson, J.J.10
  • 25
    • 0001557206 scopus 로고
    • Absolute quantitation of γ-aminobutyric acid: A receptor subunit messenger RNA by competitive polymerase chain reaction
    • Grayson D. R., Bovolin P., and Santi M.-R. (1993) Absolute quantitation of γ-aminobutyric acid: a receptor subunit messenger RNA by competitive polymerase chain reaction. Methods Neurosci. 12, 191-207.
    • (1993) Methods Neurosci. , vol.12 , pp. 191-207
    • Grayson, D.R.1    Bovolin, P.2    Santi, M.-R.3
  • 26
    • 0344827778 scopus 로고
    • Psychiatric implications of altered limbic - Hypothalamic - Pituitary - Adrenocortical activity
    • Holsboer F. (1989) Psychiatric implications of altered limbic - hypothalamic - pituitary - adrenocortical activity. Eur. Arch. Psychiatry Neurol. Sci. 23, 8302-8322.
    • (1989) Eur. Arch. Psychiatry Neurol. Sci. , vol.23 , pp. 8302-8322
    • Holsboer, F.1
  • 27
    • 0024971073 scopus 로고
    • Inositol polyphosphates and intracellular calcium release
    • Joseph S. K. and Williamson J. R. (1989) Inositol polyphosphates and intracellular calcium release. Arch. Biochem. Biophys. 273, 1-15.
    • (1989) Arch. Biochem. Biophys. , vol.273 , pp. 1-15
    • Joseph, S.K.1    Williamson, J.R.2
  • 28
    • 0028236281 scopus 로고
    • Ethanol-induced alteration in activities of cerebral phosphatidyl inositol 4,5-bisphosphate-specific and cytosol phospholipase C in the brain: Analysis using NG 108-15 cells and brains from ethanol-inhaled mice
    • Katsura M., Ohkuma S., Chen D.-Z., and Kuriyama K. (1994) Ethanol-induced alteration in activities of cerebral phosphatidyl inositol 4,5-bisphosphate-specific and cytosol phospholipase C in the brain: analysis using NG 108-15 cells and brains from ethanol-inhaled mice. Neurochem. Int. 24, 541-547.
    • (1994) Neurochem. Int. , vol.24 , pp. 541-547
    • Katsura, M.1    Ohkuma, S.2    Chen, D.-Z.3    Kuriyama, K.4
  • 31
    • 0027287698 scopus 로고
    • Differential effect of subchronic DEX treatment on serotonin-2 and β-adrenergic receptors in the rat cerebral cortex and hippocampus
    • Kuroda Y., Mikuni M., Nomura N., and Takahashi K. (1993) Differential effect of subchronic DEX treatment on serotonin-2 and β-adrenergic receptors in the rat cerebral cortex and hippocampus. Neurosci. Lett. 155, 195-198.
    • (1993) Neurosci. Lett. , vol.155 , pp. 195-198
    • Kuroda, Y.1    Mikuni, M.2    Nomura, N.3    Takahashi, K.4
  • 34
    • 0028986998 scopus 로고
    • 2 hydrolysis and regulation of phospholipase C isozymes
    • 2 hydrolysis and regulation of phospholipase C isozymes. Curr. Opin. Cell Biol. 7, 183-189.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 183-189
    • Lee, S.B.1    Rhee, S.G.2
  • 35
    • 0030823163 scopus 로고    scopus 로고
    • G-protein betagamma subunits antagonize protein kinase C-dependent phosphorylation and inhibition of phospholipase C-beta 1
    • Litosch I. (1997) G-protein betagamma subunits antagonize protein kinase C-dependent phosphorylation and inhibition of phospholipase C-beta 1. Biochem. J. 15, 701-707.
    • (1997) Biochem. J. , vol.15 , pp. 701-707
    • Litosch, I.1
  • 37
    • 0023259046 scopus 로고
    • Glucocorticoid - Biogenic amine interactions in relation to mood and behaviour
    • McEwen B. S. (1987) Glucocorticoid - biogenic amine interactions in relation to mood and behaviour. Biochem. Pharmacol. 36, 1755-1763.
    • (1987) Biochem. Pharmacol. , vol.36 , pp. 1755-1763
    • McEwen, B.S.1
  • 38
    • 0002652744 scopus 로고
    • The hippocampus: A site for modulatory interactions between steroid hormones, neurotransmitters and neuropeptides
    • Miller E. E. and MacLeod R. M., eds, Springer-Verlag, Berlin
    • McEwen B. S., Brinton R. E., Chao H. M., Coirini H., Gannon N., Gould E., O'Callagnan J., Spencer R. L., Sakai R. R., and Wooley C. S. (1990) The hippocampus: a site for modulatory interactions between steroid hormones, neurotransmitters and neuropeptides, in Neuroendocrine Perspectives (Miller E. E. and MacLeod R. M., eds), pp. 93-131. Springer-Verlag, Berlin.
    • (1990) Neuroendocrine Perspectives , pp. 93-131
    • McEwen, B.S.1    Brinton, R.E.2    Chao, H.M.3    Coirini, H.4    Gannon, N.5    Gould, E.6    O'Callagnan, J.7    Spencer, R.L.8    Sakai, R.R.9    Wooley, C.S.10
  • 39
    • 0031732606 scopus 로고    scopus 로고
    • Penetration of dexamethasone into brain glucocorticoid targets is enhanced in mdr1A P-glycoprotein knockout mice
    • Meijer O. C., de Lange E. C., Breimer D. D., de Boer A. G., Workel J. O., and de Kloet E. R. (1998) Penetration of dexamethasone into brain glucocorticoid targets is enhanced in mdr1A P-glycoprotein knockout mice. Endocrinology 4, 1789-1793.
    • (1998) Endocrinology , vol.4 , pp. 1789-1793
    • Meijer, O.C.1    De Lange, E.C.2    Breimer, D.D.3    De Boer, A.G.4    Workel, J.O.5    De Kloet, E.R.6
  • 40
    • 0022374001 scopus 로고
    • Biochemical effects of corticosteroids on neural tissues
    • Meyer J. S. (1985) Biochemical effects of corticosteroids on neural tissues. Physiol. Rev. 65, 946-1010.
    • (1985) Physiol. Rev. , vol.65 , pp. 946-1010
    • Meyer, J.S.1
  • 42
    • 0026558383 scopus 로고
    • Serotonin but not norepinephrine-induced calcium mobilization of platelets is enhanced in affective disorders
    • Mikuni M., Kagaya A., Takahashi K., and Meltzer H. Y. (1992) Serotonin but not norepinephrine-induced calcium mobilization of platelets is enhanced in affective disorders. Psychopharmacology 106, 311-314.
    • (1992) Psychopharmacology , vol.106 , pp. 311-314
    • Mikuni, M.1    Kagaya, A.2    Takahashi, K.3    Meltzer, H.Y.4
  • 43
    • 0020578673 scopus 로고
    • Norepinephrine sensitive adenylate cyclase system in rat brain: Role of adrenal corticosteroids
    • Mobley P. L., Manier D. H., and Sulser F. (1983) Norepinephrine sensitive adenylate cyclase system in rat brain: role of adrenal corticosteroids. J. Pharmacol. Exp. Ther. 226, 71-77.
    • (1983) J. Pharmacol. Exp. Ther. , vol.226 , pp. 71-77
    • Mobley, P.L.1    Manier, D.H.2    Sulser, F.3
  • 45
    • 0025882570 scopus 로고
    • Steroids and depression
    • Murphy B. E. P. (1991) Steroids and depression. J. Steroid Biochem. 38, 537-559.
    • (1991) J. Steroid Biochem. , vol.38 , pp. 537-559
    • Murphy, B.E.P.1
  • 46
    • 0023936448 scopus 로고
    • Regional distribution of phosphoinositide-specific phospholipase C activity in rat brain
    • Nishida A., Kaiya H., Tohmatsu T., Banno Y., Wakabayashi S., and Nozawa Y. (1988) Regional distribution of phosphoinositide-specific phospholipase C activity in rat brain. Neurosci. Lett 90, 354-357.
    • (1988) Neurosci. Lett , vol.90 , pp. 354-357
    • Nishida, A.1    Kaiya, H.2    Tohmatsu, T.3    Banno, Y.4    Wakabayashi, S.5    Nozawa, Y.6
  • 47
    • 0023764824 scopus 로고
    • The molecular heterogeneity of protein kinase C and its implications for cellular regulation
    • Nishizuka Y. (1988) The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 334, 661-665.
    • (1988) Nature , vol.334 , pp. 661-665
    • Nishizuka, Y.1
  • 48
    • 0028971813 scopus 로고
    • Phosphoinositide-specific phospholipase C and mitogenic signaling
    • Noh D. Y., Shin S. H., and Rhee S. G. (1995) Phosphoinositide-specific phospholipase C and mitogenic signaling. Biochim. Biophys. Acta 1242, 99-113.
    • (1995) Biochim. Biophys. Acta , vol.1242 , pp. 99-113
    • Noh, D.Y.1    Shin, S.H.2    Rhee, S.G.3
  • 49
    • 0029851918 scopus 로고    scopus 로고
    • q/11α subunit protein and phospholipase C isozymes in the rat brain
    • q/11α subunit protein and phospholipase C isozymes in the rat brain. J. Neurochem. 67, 2355-2361.
    • (1996) J. Neurochem. , vol.67 , pp. 2355-2361
    • Pandey, S.C.1
  • 53
    • 0030995012 scopus 로고    scopus 로고
    • Regulation of phosphoinositide-specific phospholipase C isozymes
    • Rhee S. G. and Bae Y. S. (1997) Regulation of phosphoinositide-specific phospholipase C isozymes. J. Biol. Chem. 272, 15045-15048.
    • (1997) J. Biol. Chem. , vol.272 , pp. 15045-15048
    • Rhee, S.G.1    Bae, Y.S.2
  • 54
    • 0026654469 scopus 로고
    • Regulation of inositol phospholipid-specific phospholipase C isozymes
    • Rhee S. G. and Choi K. D. (1992) Regulation of inositol phospholipid-specific phospholipase C isozymes. J. Biol. Chem. 267, 12393-12396.
    • (1992) J. Biol. Chem. , vol.267 , pp. 12393-12396
    • Rhee, S.G.1    Choi, K.D.2
  • 55
    • 0024403320 scopus 로고
    • Studies of inositol phospholipid-specific phospholipase C
    • Rhee S. G., Suh P. G., Ryu S. H., and Lee S. Y. (1989) Studies of inositol phospholipid-specific phospholipase C. Science 244, 546-550.
    • (1989) Science , vol.244 , pp. 546-550
    • Rhee, S.G.1    Suh, P.G.2    Ryu, S.H.3    Lee, S.Y.4
  • 57
    • 0024599394 scopus 로고
    • Brain phospholipase C isozymes: Differential mRNA localizations by in-situ hybridization
    • Ross C. A., MacCumber M. W., Glass C. E., and Snyder S. H. (1989) Brain phospholipase C isozymes: differential mRNA localizations by in-situ hybridization. Proc. Natl. Acad. Sci. USA 86, 2923-2927.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 2923-2927
    • Ross, C.A.1    MacCumber, M.W.2    Glass, C.E.3    Snyder, S.H.4
  • 60
    • 0025236842 scopus 로고
    • Adrenal steroid type I and type II receptor binding: Estimates of in vivo receptor number, occupancy, and activation with varying level of steroid
    • Spencer R. L., Young E. A., Choo P. H., and McEwen B. S. (1990) Adrenal steroid type I and type II receptor binding: estimates of in vivo receptor number, occupancy, and activation with varying level of steroid. Brain Res. 514, 37-48.
    • (1990) Brain Res. , vol.514 , pp. 37-48
    • Spencer, R.L.1    Young, E.A.2    Choo, P.H.3    McEwen, B.S.4
  • 61
    • 0025695580 scopus 로고
    • G protein diversity: A distinct class of alpha subunits is present in vertebrates and invertebrates
    • Strathmann M. and Simmon M. I. (1990) G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates. Proc. Natl. Acad. Sci. USA 87, 9113-9117.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9113-9117
    • Strathmann, M.1    Simmon, M.I.2
  • 62
    • 0023749072 scopus 로고
    • Cloning and sequencing of multiple forms of phospholipase C
    • Suh P., Ryu S., Moon K., Suh H., and Rhee S. (1988) Cloning and sequencing of multiple forms of phospholipase C. Cell 54, 161-169.
    • (1988) Cell , vol.54 , pp. 161-169
    • Suh, P.1    Ryu, S.2    Moon, K.3    Suh, H.4    Rhee, S.5
  • 63
    • 0029974368 scopus 로고    scopus 로고
    • Chronic dexamethasone administration decreases noradrenaline-stimulated, but not serotonin-stimulated, phosphoinositide metabolism in the rat brain
    • Takahashi M., Morinobu S., Totsuka S., and Endoh M. (1996) Chronic dexamethasone administration decreases noradrenaline-stimulated, but not serotonin-stimulated, phosphoinositide metabolism in the rat brain. Naunyn Schmiedebergs Arch. Pharmacol. 353, 616-620.
    • (1996) Naunyn Schmiedebergs Arch. Pharmacol. , vol.353 , pp. 616-620
    • Takahashi, M.1    Morinobu, S.2    Totsuka, S.3    Endoh, M.4
  • 65
    • 0023700693 scopus 로고
    • Molecular interactions of steroid hormone receptor with its enhanced element: Evidence for receptor dimer formation
    • Tsai S. Y., Carlstedt-Duke J., Weigel N. L., Dahlman K., Gustafsson J. A., Tsai M. J., and O'Malley B. W. (1988) Molecular interactions of steroid hormone receptor with its enhanced element: evidence for receptor dimer formation. Cell 55, 361-369.
    • (1988) Cell , vol.55 , pp. 361-369
    • Tsai, S.Y.1    Carlstedt-Duke, J.2    Weigel, N.L.3    Dahlman, K.4    Gustafsson, J.A.5    Tsai, M.J.6    O'Malley, B.W.7
  • 66
    • 0024815162 scopus 로고
    • Neuroendocrine aspects of the serotonergic hypothesis of depression
    • Van de Kar S. D. (1989) Neuroendocrine aspects of the serotonergic hypothesis of depression. Neurosci. Biobehav. Rev. 13, 327-346.
    • (1989) Neurosci. Biobehav. Rev. , vol.13 , pp. 327-346
    • Van De Kar, S.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.