Anti-Tuberculosis Activity of α -Helical Antimicrobial Peptides: De Novo Designed L- and D-Enantiomers Versus L- and D-LL37

Protein and Peptide Letters

Volumn 18, Issue 3, 2011, Pages 241-252

  Jiang, Ziqing ^a   Higgins, Michael P ^a   Whitehurst, James ^a   Kisich, Kevin O ^b   Voskuil, Martin I ^a   Hodges, Robert S ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

All D enantiomer; Antimicrobial peptides; Hemolysis; Mycobacterium tuberculosis

Indexed keywords

CATHELICIDIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE; TUBERCULOSTATIC AGENT;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CHEMICAL PHENOMENA; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; GENETICS; HEMOLYSIS; HUMAN; MICROBIOLOGICAL EXAMINATION; MOLECULAR GENETICS; MULTIDRUG RESISTANCE; MYCOBACTERIUM TUBERCULOSIS; PROTEIN SECONDARY STRUCTURE; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTITUBERCULAR AGENTS; CATHELICIDINS; DRUG DESIGN; DRUG RESISTANCE, MULTIPLE; HEMOLYSIS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; PROTEIN STRUCTURE, SECONDARY; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

MYCOBACTERIUM TUBERCULOSIS;

EID: 79951634149     PISSN: 09298665     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986611794578288     Document Type: Article

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