Over-expressing transient receptor potential cation channel 6 in podocytes induces cytoskeleton rearrangement through increases of intracellular Ca 2+and RhoA activation

Experimental Biology and Medicine

Volumn 236, Issue 2, 2011, Pages 184-193

  Jiang, Lina ^a   Ding, Jie ^a   Tsai, Haojan ^a   Li, Lin ^a   Feng, Quancheng ^a   Miao, Jing ^a   Fan, Qingfeng ^a  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

Author keywords

Cytoskeleton rearrangement; Over expressing TRPC6; Podocyte; RhoA pathway

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CALCIUM ION; COMPLEMENTARY DNA; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; F ACTIN; NEPHRIN; PLASMID DNA; RHO KINASE; SYNAPTOPODIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CHELATION; CONTROLLED STUDY; CYTOSKELETON; ELECTROPHYSIOLOGY; GENE OVEREXPRESSION; KIDNEY DISEASE; MOUSE; NONHUMAN; PLASMID; PODOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEINURIA; RECEPTOR DOWN REGULATION; TRANSIENT TRANSFECTION;

ANIMALS; CALCIUM; CATIONS, DIVALENT; CYTOSKELETON; GENE EXPRESSION; MEMBRANE PROTEINS; MICE; MICROFILAMENT PROTEINS; PODOCYTES; RHO GTP-BINDING PROTEINS; TRPC CATION CHANNELS;

ANIMALIA;

EID: 79951617575     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2010.010237     Document Type: Article

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