Mutagenicity of PFOA in mammalian cells: Role of mitochondria-dependent reactive oxygen species

Environmental Science and Technology

Volumn 45, Issue 4, 2011, Pages 1638-1644

  Zhao, Guoping ^a   Wang, Jun ^a   Wang, Xiaofei ^a   Chen, Shaopeng ^a   Zhao, Ye ^a   Gu, Feng ^a   Xu, An ^a,b   Wu, Lijun ^a  

^a HEFEI INSTITUTES OF PHYSICAL SCIENCE   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER INDUCTION; CASPASES; MAMMALIAN CELLS; MUTAGENIC EFFECT; MUTAGENICITY; MUTATION INDUCTION; PERFLUOROOCTANOIC ACID; REACTIVE OXYGEN SPECIES; SUPEROXIDE ANIONS;

DISEASES; MAMMALS; NITRIC OXIDE; NITROGEN OXIDES; OXYGEN;

MITOCHONDRIA;

CASPASE 3; CASPASE 7; CASPASE 9; MITOCHONDRIAL DNA; NITROGEN OXIDE; PERFLUOROOCTANOIC ACID; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; CASPASE; FLUOROCARBON; MUTAGENIC AGENT; OCTANOIC ACID DERIVATIVE; POLLUTANT;

CANCER; CYTOLOGY; INHIBITOR; MITOCHONDRIAL DNA; MUTAGENICITY; OXYGEN;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL CULTURE; CELL SURVIVAL; CELL VIABILITY; CHROMOSOME 11; CYTOTOXICITY; ENZYME ACTIVITY; EXPOSURE; HUMAN; HUMAN CELL; HYBRID; INDUCED MUTATION; MAMMAL CELL; MITOCHONDRION; MUTAGENICITY; NONHUMAN; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; HAMSTER; METABOLISM; NEOPLASM; POLLUTANT; TOXICITY;

CRICETINAE; MAMMALIA;

ANIMALS; CAPRYLATES; CASPASES; CRICETINAE; DNA, MITOCHONDRIAL; ENVIRONMENTAL POLLUTANTS; FLUOROCARBONS; HUMANS; MUTAGENS; NEOPLASMS; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

EID: 79951609040     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es1026129     Document Type: Article

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