Synthesis of n-squalenoyl cytarabine and evaluation of its affinity with phospholipid bilayers and monolayers

International Journal of Pharmaceutics

Volumn 406, Issue 1-2, 2011, Pages 69-77

  Sarpietro, Maria Grazia ^a   Ottimo, Sara ^a   Giuffrida, Maria Chiara ^a   Rocco, Flavio ^b   Ceruti, Maurizio ^b   Castelli, Francesco ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

Biomembrane model; Cytarabine; DSC; Langmuir Blodgett; n Squalenoyl cytarabine; Prodrug

Indexed keywords

1,1',2 TRIS NOR SQUALENE ACID; 4 (N 1,1',2 TRIS NOR SQUALENOYL) 1 BETA DEXTRO (ARABINOFURANOSYL)CYTOSINE (SQUALENOYL CYTARABINE); CYTARABINE; DIMYRISTOYLPHOSPHATIDYLCHOLINE; DRUG CARRIER; N SQUALENOYL CYTARABINE; PHOSPHOLIPID; PRODRUG; UNCLASSIFIED DRUG;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BINDING; DRUG SYNTHESIS; LANGMUIR BLODGETT FILM; LIPID BILAYER; LIPID MONOLAYER; LIPOPHILICITY; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; CYTARABINE; DIMYRISTOYLPHOSPHATIDYLCHOLINE; LIPID BILAYERS; LIPOSOMES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MOLECULAR STRUCTURE; PRODRUGS; SQUALENE;

EID: 79951578902     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.12.038     Document Type: Article

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