Enhancement of gemcitabine affinity for biomembranes by conjugation with squalene: Differential scanning calorimetry and Langmuir-Blodgett studies using biomembrane models

Journal of Colloid and Interface Science

Volumn 316, Issue 1, 2007, Pages 43-52

  Castelli, Francesco ^a   Sarpietro, Maria Grazia ^a   Micieli, Dorotea ^a   Stella, Barbara ^b   Rocco, Flavio ^b   Cattel, Luigi ^b  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

Biomembrane models; Differential scanning calorimetry; Dimyristoylphosphatidylcholine; Gemcitabine; Langmuir Blodgett; Lipophilic gemcitabine derivative

Indexed keywords

BIOLOGICAL MEMBRANES; DIFFERENTIAL SCANNING CALORIMETRY; LANGMUIR BLODGETT FILMS; MOLECULAR DYNAMICS; PHOSPHOLIPIDS;

BIOMEMBRANE MODELS; DIMYRISTOYLPHOSPHATIDYLCHOLINE; GEMCITABINE; LIPOPHILIC GEMCITABINE DERIVATIVE;

DRUG PRODUCTS;

DIMYRISTOYLPHOSPHATIDYLCHOLINE; GEMCITABINE; LIPOSOME; PHOSPHATIDYLCHOLINE; PRODRUG; SQUALENE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING KINETICS; CELL MEMBRANE; CONJUGATION; CONTROLLED RELEASE FORMULATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BINDING; DRUG DELIVERY SYSTEM; LANGMUIR BLODGETT FILM; MAMMAL CELL; MEMBRANE MODEL; MOLECULAR INTERACTION; MONOLAYER CULTURE; NONHUMAN; PRESSURE MEASUREMENT; PRIORITY JOURNAL; SURFACE PROPERTY;

CALORIMETRY, DIFFERENTIAL SCANNING; DEOXYCYTIDINE; DIMYRISTOYLPHOSPHATIDYLCHOLINE; HEAT; LIPID BILAYERS; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE; PHASE TRANSITION; SQUALENE; SURFACE PROPERTIES;

EID: 34948844031     PISSN: 00219797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcis.2007.07.064     Document Type: Article

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