Characterization of lipophilic gemcitabine prodrug-liposomal membrane interaction by differential scanning calorimetry

Molecular Pharmaceutics

Volumn 3, Issue 6, 2006, Pages 737-744

  Castelli, Francesco ^a   Sarpietro, Maria Grazia ^a   Ceruti, Maurizio ^b   Rocco, Flavio ^b   Cattel, Luigi ^b  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

Calorimetry; Gemcitabine; Lipophilic gemcitabine derivatives; Liposomes; Pharmacokinetics

Indexed keywords

2',2' DIFLUORODEOXYURIDINE; 4 (N)LAUROYLGEMCITABINE; 4 (N)STEAROYLGEMCITABINE; 4 (N)VALEROYLGEMCITABINE; DIMYRISTOYLPHOSPHATIDYLCHOLINE; DISTEAROYLPHOSPHATIDYLCHOLINE; DRUG METABOLITE; FATTY ACID; GEMCITABINE; LIPOSOME; PHOSPHOLIPID; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; CELL SURFACE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG PENETRATION; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; DRUG TRANSPORT; LIPID VESICLE; LIPOPHILICITY; PRIORITY JOURNAL;

CALORIMETRY, DIFFERENTIAL SCANNING; DEOXYCYTIDINE; DIMYRISTOYLPHOSPHATIDYLCHOLINE; FATTY ACIDS; LIPID BILAYERS; LIPOSOMES; MEMBRANES, ARTIFICIAL; MODELS, BIOLOGICAL; PERMEABILITY; PHOSPHATIDYLCHOLINES; PRODRUGS;

EID: 33846131989     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp060059y     Document Type: Article

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