메뉴 건너뛰기




Volumn 38, Issue 2, 2011, Pages 1315-1320

KRAS, BRAF, EGFR and HER2 gene status in a Spanish population of colorectal cancer

Author keywords

BRAF; Colorectal cancer; EGFR; HER2; KRAS; Mutation

Indexed keywords

ADULT; AGED; AMINO ACID SUBSTITUTION; ARTICLE; BRAF MURINE SARCOMA VIRAL ONCOGENE HOMOLOG B1; COLORECTAL CANCER; CONTROLLED STUDY; EPIDERMAL GROWTH FACTOR RECEPTOR GENE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE AMPLIFICATION; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 GENE; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MUTATIONAL ANALYSIS; ONCOGENE K RAS; SPAIN;

EID: 79951578834     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-010-0232-x     Document Type: Article
Times cited : (38)

References (33)
  • 1
    • 0037260139 scopus 로고    scopus 로고
    • Cancer statistics
    • 10.3322/canjclin.53.1.5 12568441
    • A Jemal, et al. 2003 Cancer statistics CA Cancer J Clin 53 1 5 26 10.3322/canjclin.53.1.5 12568441
    • (2003) CA Cancer J Clin , vol.53 , Issue.1 , pp. 5-26
    • Jemal, A.1
  • 2
    • 20444421216 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-targeted treatment for advanced colorectal carcinoma
    • DOI 10.1002/cncr.21123
    • AP Venook 2005 Epidermal growth factor receptor-targeted treatment for advanced colorectal carcinoma Cancer 103 12 2435 2446 1:CAS:528: DC%2BD2MXlvVCktL4%3D 10.1002/cncr.21123 15880563 (Pubitemid 40800520)
    • (2005) Cancer , vol.103 , Issue.12 , pp. 2435-2446
    • Venook, A.P.1
  • 5
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: The complexity of targeted inhibitors
    • DOI 10.1038/nrc1609
    • NE Hynes HA Lane 2005 ERBB receptors and cancer: the complexity of targeted inhibitors Nat Rev Cancer 5 5 341 354 1:CAS:528:DC%2BD2MXjslertb0%3D 10.1038/nrc1609 15864276 (Pubitemid 40637826)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 6
    • 33746485766 scopus 로고    scopus 로고
    • Epidermal Growth Factor Receptor Targeting in Cancer
    • DOI 10.1053/j.seminoncol.2006.04.003, PII S0093775406001771
    • J Mendelsohn J Baselga 2006 Epidermal growth factor receptor targeting in cancer Semin Oncol 33 4 369 385 1:CAS:528:DC%2BD28XpsVersLk%3D 10.1053/j.seminoncol.2006.04.003 16890793 (Pubitemid 44142736)
    • (2006) Seminars in Oncology , vol.33 , Issue.4 , pp. 369-385
    • Mendelsohn, J.1    Baselga, J.2
  • 7
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • DOI 10.1038/nrc969
    • J Downward 2003 Targeting RAS signalling pathways in cancer therapy Nat Rev Cancer 3 1 11 22 1:CAS:528:DC%2BD38XpvVertbo%3D 10.1038/nrc969 12509763 (Pubitemid 37328883)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.1 , pp. 11-22
    • Downward, J.1
  • 8
    • 0037805547 scopus 로고    scopus 로고
    • RAS oncogenes: The first 30 years
    • DOI 10.1038/nrc1097
    • M Malumbres M Barbacid 2003 RAS oncogenes: the first 30 years Nat Rev Cancer 3 6 459 465 1:CAS:528:DC%2BD3sXktFOnsbs%3D 10.1038/nrc1097 12778136 (Pubitemid 37328850)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.6 , pp. 459-465
    • Malumbres, M.1    Barbacid, M.2
  • 9
    • 33947594129 scopus 로고    scopus 로고
    • Hyperactive Ras in developmental disorders and cancer
    • DOI 10.1038/nrc2109, PII NRC2109
    • S Schubbert K Shannon G Bollag 2007 Hyperactive Ras in developmental disorders and cancer Nat Rev Cancer 7 4 295 308 1:CAS:528:DC%2BD2sXjtlyhtLs%3D 10.1038/nrc2109 17384584 (Pubitemid 46480970)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.4 , pp. 295-308
    • Schubbert, S.1    Shannon, K.2    Bollag, G.3
  • 11
    • 0036739336 scopus 로고    scopus 로고
    • Specific codon 13 K-ras mutations are predictive of clinical outcome in colorectal cancer patients, whereas codon 12 K-ras mutations are associated with mucinous histotype
    • 1:STN:280:DC%2BD38vjvVGisQ%3D%3D 10.1093/annonc/mdf226 12196370
    • V Bazan, et al. 2002 Specific codon 13 K-ras mutations are predictive of clinical outcome in colorectal cancer patients, whereas codon 12 K-ras mutations are associated with mucinous histotype Ann Oncol 13 9 1438 1446 1:STN:280:DC%2BD38vjvVGisQ%3D%3D 10.1093/annonc/mdf226 12196370
    • (2002) Ann Oncol , vol.13 , Issue.9 , pp. 1438-1446
    • Bazan, V.1
  • 12
    • 34047248571 scopus 로고    scopus 로고
    • Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies
    • DOI 10.1158/0008-5472.CAN-06-4158
    • S Benvenuti, et al. 2007 Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies Cancer Res 67 6 2643 2648 1:CAS:528:DC%2BD2sXivV2ns7w%3D 10.1158/0008-5472.CAN-06-4158 17363584 (Pubitemid 46548951)
    • (2007) Cancer Research , vol.67 , Issue.6 , pp. 2643-2648
    • Benvenuti, S.1    Sartore-Bianchi, A.2    Di Nicolantonio, F.3    Zanon, C.4    Moroni, M.5    Veronese, S.6    Siena, S.7    Bardelli, A.8
  • 15
    • 33646228635 scopus 로고    scopus 로고
    • KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer
    • 1:CAS:528:DC%2BD28XjsFSlsb0%3D 10.1158/0008-5472.CAN-06-0191 16618717
    • A Lievre, et al. 2006 KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer Cancer Res 66 8 3992 3995 1:CAS:528:DC%2BD28XjsFSlsb0%3D 10.1158/0008-5472.CAN-06-0191 16618717
    • (2006) Cancer Res , vol.66 , Issue.8 , pp. 3992-3995
    • Lievre, A.1
  • 16
    • 34247562353 scopus 로고    scopus 로고
    • Predicting response to epidermal growth factor receptor-targeted therapy in colorectal cancer
    • DOI 10.1586/14737140.7.4.503
    • R Adams T Maughan 2007 Predicting response to epidermal growth factor receptor-targeted therapy in colorectal cancer Expert Rev Anticancer Ther 7 4 503 518 1:CAS:528:DC%2BD2sXkt1Wqsr0%3D 10.1586/14737140.7.4.503 17428171 (Pubitemid 46681806)
    • (2007) Expert Review of Anticancer Therapy , vol.7 , Issue.4 , pp. 503-518
    • Adams, R.1    Maughan, T.2
  • 17
    • 33646712747 scopus 로고    scopus 로고
    • Mechanisms of disease: Understanding resistance to HER2-targeted therapy in human breast cancer
    • DOI 10.1038/ncponc0509, PII N0509
    • R Nahta, et al. 2006 Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer Nat Clin Pract Oncol 3 5 269 280 1:CAS:528:DC%2BD28Xltlagtbg%3D 10.1038/ncponc0509 16683005 (Pubitemid 43731112)
    • (2006) Nature Clinical Practice Oncology , vol.3 , Issue.5 , pp. 269-280
    • Nahta, R.1    Yu, D.2    Hung, M.-C.3    Hortobagyi, G.N.4    Esteva, F.J.5
  • 18
    • 34548546535 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab
    • DOI 10.1158/0008-5472.CAN-07-0589
    • Y Lu, et al. 2007 Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab Cancer Res 67 17 8240 8247 1:CAS:528: DC%2BD2sXpvFKjurs%3D 10.1158/0008-5472.CAN-07-0589 17804738 (Pubitemid 47395161)
    • (2007) Cancer Research , vol.67 , Issue.17 , pp. 8240-8247
    • Lu, Y.1    Li, X.2    Liang, K.3    Luwor, R.4    Siddik, Z.H.5    Mills, G.B.6    Mendelsohn, J.7    Fan, Z.8
  • 21
  • 22
    • 67649989634 scopus 로고    scopus 로고
    • Disease-free survival according to degree of HER2 amplification for patients treated with adjuvant chemotherapy with or without 1 year of trastuzumab: The HERA Trial
    • 1:CAS:528:DC%2BD1MXoslyis70%3D 10.1200/JCO.2008.19.7939 19364966
    • M Dowsett, et al. 2009 Disease-free survival according to degree of HER2 amplification for patients treated with adjuvant chemotherapy with or without 1 year of trastuzumab: the HERA Trial J Clin Oncol 27 18 2962 2969 1:CAS:528:DC%2BD1MXoslyis70%3D 10.1200/JCO.2008.19.7939 19364966
    • (2009) J Clin Oncol , vol.27 , Issue.18 , pp. 2962-2969
    • Dowsett, M.1
  • 25
    • 0034307747 scopus 로고    scopus 로고
    • Mode of action and application of Scorpion primers to mutation detection
    • 1:CAS:528:DC%2BD3cXntlKmurk%3D 10.1093/nar/28.19.3752 11000267
    • N Thelwell, et al. 2000 Mode of action and application of Scorpion primers to mutation detection Nucleic Acids Res 28 19 3752 3761 1:CAS:528:DC%2BD3cXntlKmurk%3D 10.1093/nar/28.19.3752 11000267
    • (2000) Nucleic Acids Res , vol.28 , Issue.19 , pp. 3752-3761
    • Thelwell, N.1
  • 26
    • 0032839195 scopus 로고    scopus 로고
    • Detection of PCR products using self-probing amplicons and fluorescence
    • DOI 10.1038/11751
    • D Whitcombe, et al. 1999 Detection of PCR products using self-probing amplicons and fluorescence Nat Biotechnol 17 8 804 807 1:CAS:528: DyaK1MXmtFahsr0%3D 10.1038/11751 10429248 (Pubitemid 29365111)
    • (1999) Nature Biotechnology , vol.17 , Issue.8 , pp. 804-807
    • Whitcombe, D.1    Theaker, J.2    Guy, S.P.3    Brown, T.4    Little, S.5
  • 28
    • 42649145667 scopus 로고    scopus 로고
    • Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
    • 1:CAS:528:DC%2BD1cXltlWhsrw%3D 10.1200/JCO.2007.14.7116 18316791
    • RG Amado, et al. 2008 Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer J Clin Oncol 26 10 1626 1634 1:CAS:528:DC%2BD1cXltlWhsrw%3D 10.1200/JCO.2007.14.7116 18316791
    • (2008) J Clin Oncol , vol.26 , Issue.10 , pp. 1626-1634
    • Amado, R.G.1
  • 29
    • 57449095367 scopus 로고    scopus 로고
    • Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer
    • 1:CAS:528:DC%2BD1MXotFemsA%3D%3D 10.1200/JCO.2008.18.0786 19001320
    • F Di Nicolantonio, et al. 2008 Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer J Clin Oncol 26 35 5705 5712 1:CAS:528:DC%2BD1MXotFemsA%3D%3D 10.1200/JCO.2008.18.0786 19001320
    • (2008) J Clin Oncol , vol.26 , Issue.35 , pp. 5705-5712
    • Di Nicolantonio, F.1
  • 30
    • 61749084470 scopus 로고    scopus 로고
    • Is overexpression of HER-2 a predictor of prognosis in colorectal cancer?
    • 10.1186/1471-2407-9-1 19118499
    • DO Kavanagh, et al. 2009 Is overexpression of HER-2 a predictor of prognosis in colorectal cancer? BMC Cancer 9 1 10.1186/1471-2407-9-1 19118499
    • (2009) BMC Cancer , vol.9 , pp. 1
    • Kavanagh, D.O.1
  • 31
    • 3343024502 scopus 로고    scopus 로고
    • Protein overexpression and gene amplification of HER-2 and EGFR in colorectal cancers: An immunohistochemical and fluorescent in situ hybridization study
    • DOI 10.1038/modpathol.3800137
    • A Ooi, et al. 2004 Protein overexpression and gene amplification of HER-2 and EGFR in colorectal cancers: an immunohistochemical and fluorescent in situ hybridization study Mod Pathol 17 8 895 904 1:CAS:528:DC%2BD2cXmvVOltrk%3D 10.1038/modpathol.3800137 15143334 (Pubitemid 38993773)
    • (2004) Modern Pathology , vol.17 , Issue.8 , pp. 895-904
    • Ooi, A.1    Takehana, T.2    Li, X.3    Suzuki, S.4    Kunitomo, K.5    Iino, H.6    Fujii, H.7    Takeda, Y.8    Dobashi, Y.9
  • 32
    • 33745058476 scopus 로고    scopus 로고
    • HER 2/neu protein expression in colorectal cancer
    • DOI 10.1186/1471-2407-6-123
    • B Schuell, et al. 2006 HER 2/neu protein expression in colorectal cancer BMC Cancer 6 123 1:CAS:528:DC%2BD28XkvV2qtL4%3D 10.1186/1471-2407-6-123 16681853 (Pubitemid 43880548)
    • (2006) BMC Cancer , vol.6 , pp. 123
    • Schuell, B.1    Gruenberger, T.2    Scheithauer, W.3    Zielinski, Ch.4    Wrba, F.5
  • 33
    • 42649094858 scopus 로고    scopus 로고
    • EGFR FISH in colorectal cancer: What is the current reality?
    • DOI 10.1016/S1470-2045(08)70109-8, PII S1470204508701098
    • M Moroni, et al. 2008 EGFR FISH in colorectal cancer: what is the current reality? Lancet Oncol 9 5 402 403 10.1016/S1470-2045(08)70109-8 18452847 (Pubitemid 351597789)
    • (2008) The Lancet Oncology , vol.9 , Issue.5 , pp. 402-403
    • Moroni, M.1    Sartore-Bianchi, A.2    Veronese, S.3    Siena, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.