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Volumn 36, Issue 4, 2011, Pages 819-826

Differential effects of 5-HTTLPR genotypes on inhibition of negative emotional information following acute stress exposure and tryptophan challenge

Author keywords

5 HTTLPR; emotion processing; serotonin; stress; tryptophan

Indexed keywords

PLACEBO; SEROTONIN; SEROTONIN TRANSPORTER; TRYPTOPHAN;

EID: 79951514300     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2010.221     Document Type: Article
Times cited : (35)

References (58)
  • 1
    • 0028333654 scopus 로고
    • PET studies of presynaptic monoamine metabolism in depressed patients and healthy volunteers
    • Agren H, Reibring L (1994). PET studies of presynaptic mono-amine metabolism in depressed patients and healthy volunteers. Pharmacopsychiatry 27: 2-6. (Pubitemid 24078981)
    • (1994) Pharmacopsychiatry , vol.27 , Issue.1 , pp. 2-6
    • Agren, H.1    Reibring, L.2
  • 2
    • 68949175518 scopus 로고    scopus 로고
    • Association of the serotonin ransporter gene promoter region (5-HTTLPR) polymorphism with biased attention for emotional stimuli
    • Beevers CG, Wells TT, Ellis AJ, McGeary J (2009). Association of the serotonin ransporter gene promoter region (5-HTTLPR) polymorphism with biased attention for emotional stimuli. J Abnorm Psychol 118: 670-681.
    • (2009) J Abnorm Psychol , vol.118 , pp. 670-681
    • Beevers, C.G.1    Wells, T.T.2    Ellis, A.J.3    McGeary, J.4
  • 3
    • 0016190722 scopus 로고
    • Rapid depletion of serum tryptophan, brain tryptophan, serotonin and 5-hydroxyindoleacetic acid by a tryptophan-free diet
    • Biggio G, Fadda F, Fanni P, Tagliamonte A, Gessa GL (1974). Rapid depletion of serum tryptophan, brain tryptophan, serotonin and 5-hydroxyindoleacetic acid by a tryptophan-free diet. Life Sci 14: 1321-1329.
    • (1974) Life Sci , vol.14 , pp. 1321-1329
    • Biggio, G.1    Fadda, F.2    Fanni, P.3    Tagliamonte, A.4    Gessa, G.L.5
  • 6
    • 37549022670 scopus 로고    scopus 로고
    • Serotoninergic regulation of emotional and behavioural control processes
    • DOI 10.1016/j.tics.2007.10.011, PII S1364661307003051
    • Cools R, Roberts AC, Robbins TW (2008). Serotoninergic regulation of emotional and behavioural control processes. Trends cogn Sci 12: 31-40. (Pubitemid 50012215)
    • (2008) Trends in Cognitive Sciences , vol.12 , Issue.1 , pp. 31-40
    • Cools, R.1    Roberts, A.C.2    Robbins, T.W.3
  • 7
    • 0028178126 scopus 로고
    • 5-HT1A receptor sensitivity in major depression. A neuroendocrine study with buspirone
    • Cowen PJ, Power AC, Ware CJ, Anderson IM (1994). 5-HT1A receptor sensitivity in major depression. A neuroendocrine study with buspirone. Br J Psychiatry 164: 372-379.
    • (1994) Br J Psychiatry , vol.164 , pp. 372-379
    • Cowen, P.J.1    Power, A.C.2    Ware, C.J.3    Anderson, I.M.4
  • 10
    • 77953105171 scopus 로고    scopus 로고
    • Understanding vulnerability for depression from a cognitive neuroscience perspective: A reappraisal of attentional factors and a new conceptual framework
    • De Raedt R, Koster EHW (2010). Understanding vulnerability for depression from a cognitive neuroscience perspective: a reappraisal of attentional factors and a new conceptual framework. Cogn Affect Behav Neurosci 10: 50-70.
    • (2010) Cogn Affect Behav Neurosci , vol.10 , pp. 50-70
    • De Raedt, R.1    Ehw, K.2
  • 11
    • 0025318311 scopus 로고
    • Serotonin function and the mechanism of antidepressant action: Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan
    • Delgado PL, Charney DS, Price LH, Aghajanian GK, Landis H, Heninger GR (1990). Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan. Arch Gen Psychiatry 47: 411-418. (Pubitemid 20161259)
    • (1990) Archives of General Psychiatry , vol.47 , Issue.5 , pp. 411-418
    • Delgado, P.L.1    Charney, D.S.2    Price, L.H.3    Aghajanian, G.K.4    Landis, H.5    Heninger, G.R.6
  • 12
    • 0027146133 scopus 로고
    • Monoamines and the mechanism of antidepressant action: Effects of catecholamine depletion on mood of patients treated with antidepressants
    • Delgado PL, Miller HL, Salomon RM, Licinio J, Heninger GR, Gelenberg AJ et al (1993). Monoamines and the mechanism of antidepressant action: effects of catecholamine depletion on mood of patients treated with antidepressants. Psychopharmacol Bull 29: 389-396. (Pubitemid 24001308)
    • (1993) Psychopharmacology Bulletin , vol.29 , Issue.3 , pp. 389-396
    • Delgado, P.L.1    Miller, H.L.2    Salomon, R.M.3    Licinio, J.4    Heninger, G.R.5    Gelenberg, A.J.6    Charney, D.S.7
  • 13
    • 2442604444 scopus 로고    scopus 로고
    • Acute stressors and cortisol responses: A theoretical integration and synthesis of laboratory research
    • DOI 10.1037/0033-2909.130.3.355
    • Dickerson SS, Kemeny ME (2004). Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research. Psychol Bull 130: 355-391. (Pubitemid 38614661)
    • (2004) Psychological Bulletin , vol.130 , Issue.3 , pp. 355-391
    • Dickerson, S.S.1    Kemeny, M.E.2
  • 14
    • 34547135198 scopus 로고    scopus 로고
    • Serotonin by stress interaction: A susceptibility factor for the development of depression?
    • DOI 10.1177/0269881106075588
    • Firk C, Markus CR (2007). Review: Serotonin by stress interaction: a susceptibility factor for the development of depression? J Psychopharmacol 21: 538-544. (Pubitemid 47106930)
    • (2007) Journal of Psychopharmacology , vol.21 , Issue.5 , pp. 538-544
    • Firk, C.1    Markus, C.R.2
  • 15
    • 63449141881 scopus 로고    scopus 로고
    • Differential effects of 5-HTTLPR genotypes on mood, memory and attention bias following acute tryptophan depletion and stress exposure
    • Firk C, Markus CR (2009). Differential effects of 5-HTTLPR genotypes on mood, memory and attention bias following acute tryptophan depletion and stress exposure. Psychopharmacology (Berl) 203: 805-818.
    • (2009) Psychopharmacology (Berl) , vol.203 , pp. 805-818
    • Firk, C.1    Markus, C.R.2
  • 16
    • 0042433251 scopus 로고    scopus 로고
    • Glucocorticoid-regulated human serotonin transporter (5-HTT) expression is modulated by the 5-HTT gene-promotor-linked polymorphic region
    • Glatz K, Mossner R, Heils A, Lesch KP (2003). Glucocorticoid-regulated human serotonin transporter (5-HTT) expression is modulated by the 5-HTT gene-promotor-linked polymorphic region. J Neurochem 86: 1072-1078. (Pubitemid 37022183)
    • (2003) Journal of Neurochemistry , vol.86 , Issue.5 , pp. 1072-1078
    • Glatz, K.1    Mossner, R.2    Heils, A.3    Lesch, K.P.4
  • 17
    • 33744550488 scopus 로고    scopus 로고
    • Deficient inhibition of emotional information in depression
    • DOI 10.1016/j.jad.2006.03.007, PII S0165032706001200
    • Goeleven E, De Raedt R, Baert S, Koster EH (2006). Deficient inhibition of emotional information in depression. J Affect Disord 93: 149-157. (Pubitemid 43816063)
    • (2006) Journal of Affective Disorders , vol.93 , Issue.1-3 , pp. 149-157
    • Goeleven, E.1    De Raedt, R.2    Baert, S.3    Koster, E.H.W.4
  • 18
    • 41449090413 scopus 로고    scopus 로고
    • HPA Axis Reactivity: A Mechanism Underlying the Associations Among 5-HTTLPR, Stress, and Depression
    • DOI 10.1016/j.biopsych.2007.10.008, PII S0006322307009912
    • Gotlib IH, Joormann J, Minor KL, Hallmayer J (2008). HPA axis reactivity: a mechanism underlying the associations among 5-HTTLPR, stress, and depression. Biol Psychiatry 63: 847-851. (Pubitemid 351458452)
    • (2008) Biological Psychiatry , vol.63 , Issue.9 , pp. 847-851
    • Gotlib, I.H.1    Joormann, J.2    Minor, K.L.3    Hallmayer, J.4
  • 19
    • 24044555935 scopus 로고    scopus 로고
    • Selective attention in dysphoric individuals: The role of affective interference and inhibition
    • DOI 10.1007/s10608-005-5753-6
    • Gotlib IH, Neubauer YD, Joorman J (2005). Selective attention in dysphoric individuals: the role of affective interference and inhibition. Cognit ther res 29: 417-432. (Pubitemid 41225051)
    • (2005) Cognitive Therapy and Research , vol.29 , Issue.4 , pp. 417-432
    • Gotlib, I.H.1    Yue, D.N.2    Joormann, J.3
  • 20
    • 33645799676 scopus 로고    scopus 로고
    • The serotonin transporter and the genetics of affect regulation: The role of the serotonin transporter in neural function
    • Hariri AR, Holmes A (2006). The serotonin transporter and the genetics of affect regulation: the role of the serotonin transporter in neural function. Trends cogn Sci 10: 182-191.
    • (2006) Trends Cogn Sci , vol.10 , pp. 182-191
    • Hariri, A.R.1    Holmes, A.2
  • 22
    • 12344328265 scopus 로고    scopus 로고
    • An expanded evaluation of the relationship of four alleles to the level of response to alcohol and the alcoholism risk
    • DOI 10.1097/01.ALC.0000150008.68473.62
    • Hu X, Oroszi G, Chun J, Smith TL, Goldman D, Schuckit MA (2005). An expanded evaluation of the relationship of four alleles to the level of response to alcohol and the alcoholism risk. Alcohol Clin Exp Res 29: 8-16. (Pubitemid 40129206)
    • (2005) Alcoholism: Clinical and Experimental Research , vol.29 , Issue.1 , pp. 8-16
    • Hu, X.1    Oroszi, G.2    Chun, J.3    Smith, T.L.4    Goldman, D.5    Schuckit, M.A.6
  • 23
    • 30544453235 scopus 로고    scopus 로고
    • Immune, endocrine and cardiovascular responses to controllable and uncontrollable acute stress
    • DOI 10.1016/j.biopsycho.2005.04.002, PII S0301051105000803
    • Isowa T, Ohira H, Murashima S (2006). Immune, endocrine and cardiovascular responses to controllable and uncontrollable acute stress. Biol Psychol 71: 202-213. (Pubitemid 43082249)
    • (2006) Biological Psychology , vol.71 , Issue.2 , pp. 202-213
    • Isowa, T.1    Ohira, H.2    Murashima, S.3
  • 24
    • 33748324559 scopus 로고    scopus 로고
    • Stress-related negative affectivity and genetically altered serotonin transporter function: Evidence of synergism in shaping risk of depression
    • DOI 10.1001/archpsyc.63.9.989
    • Jacobs N, Kenis G, Peeters F, Derom C, Vlietinck R, van Os J (2006). Stress-related negative affectivity and genetically altered serotonin transporter function: evidence of synergism in shaping risk of depression. Arch Gen Psychiatry 63: 989-996. (Pubitemid 44330457)
    • (2006) Archives of General Psychiatry , vol.63 , Issue.9 , pp. 989-996
    • Jacobs, N.1    Kenis, G.2    Peeters, F.3    Derom, C.4    Vlietinck, R.5    Van Os, J.6
  • 25
    • 34249306939 scopus 로고    scopus 로고
    • Serotonergic vulnerability and depression: Assumptions, experimental evidence and implications
    • DOI 10.1038/sj.mp.4001920, PII 4001920
    • Jans LA, Riedel WJ, Markus CR, Blokland A (2007). Serotonergic vulnerability and depression: assumptions, experimental evidence and implications. Mol Psychiatry 12: 522-543. (Pubitemid 46816766)
    • (2007) Molecular Psychiatry , vol.12 , Issue.6 , pp. 522-543
    • Jans, L.A.W.1    Riedel, W.J.2    Markus, C.R.3    Blokland, A.4
  • 26
    • 1242348964 scopus 로고    scopus 로고
    • Attentional bias in dysphoria: The role of inhibitory processes
    • DOI 10.1080/02699930244000480
    • Joormann J (2004). Attentional bias in dysphoria; the role of inhibitory processes. Cogn Emot 18: 125-147. (Pubitemid 38128359)
    • (2004) Cognition and Emotion , vol.18 , Issue.1 , pp. 125-147
    • Joormann, J.1
  • 28
    • 79951514383 scopus 로고    scopus 로고
    • Effects of repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex on the attentional processing of emotional information in major depression: A pilot study
    • in press
    • Leyman L, De Raedt R, Vanderhasselt MA, Baeken C (2010). Effects of repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex on the attentional processing of emotional information in major depression: A pilot study. Psychiatry Research (in press).
    • (2010) Psychiatry Research
    • Leyman, L.1    De Raedt, R.2    Vanderhasselt, M.A.3    Baeken, C.4
  • 30
    • 0025262152 scopus 로고
    • Suppressant effects of dexamethasone on the availability of plasma L-tryptophan and tyrosine in healthy controls and in depressed patients
    • Maes M, Jacobs MP, Suy E, Minner B, Leclercq C, Christiaens F et al (1990). Suppressant effects of dexamethasone on the availability of plasma L-tryptophan and tyrosine in healthy controls and in depressed patients. Acta Psychiatr Scand 81: 19-23. (Pubitemid 20096983)
    • (1990) Acta Psychiatrica Scandinavica , vol.81 , Issue.1 , pp. 19-23
    • Maes, M.1    Jacobs, M.-P.2    Suy, E.3    Minner, B.4    Leclercq, C.5    Christiaens, F.6    Raus, J.7
  • 31
    • 0000587671 scopus 로고
    • The serotonin hypothesis of major depression
    • Bloom FE, Kupfer DJ (eds) Raven Press: New York
    • Maes M, Meltzer HY (1995). The serotonin hypothesis of major depression. In: Bloom FE, Kupfer DJ (eds) Psychopharmacology: The Fourth Generation of Progress. Raven Press: New York, pp 933-944.
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 933-944
    • Maes, M.1    Meltzer, H.Y.2
  • 34
    • 70449531480 scopus 로고    scopus 로고
    • Differential effects of tri-allelic 5-HTTLPR polymorphisms in healthy subjects on mood and stress performance after tryptophan challenge
    • Markus C, Firk C (2009). Differential effects of tri-allelic 5-HTTLPR polymorphisms in healthy subjects on mood and stress performance after tryptophan challenge. Neuropsycho-pharmacology 34: 2667-2674.
    • (2009) Neuropsycho-pharmacology , vol.34 , pp. 2667-2674
    • Markus, C.1    Firk, C.2
  • 35
    • 34547933453 scopus 로고    scopus 로고
    • Effects of carbohydrates on brain tryptophan availability and stress performance
    • DOI 10.1016/j.biopsycho.2007.06.003, PII S030105110700110X
    • Markus CR (2007). Effects of carbohydrates on brain tryptophan availability and stress performance. Biol Psychol 76: 83-90. (Pubitemid 47268631)
    • (2007) Biological Psychology , vol.76 , Issue.1-2 , pp. 83-90
    • Markus, C.R.1
  • 36
    • 54049145467 scopus 로고    scopus 로고
    • Effect of different tryptophan sources on amino acids availability to the brain and mood in healthy volunteers
    • Markus CR, Firk C, Gerhardt C, Kloek J, Smolders GF (2008). Effect of different tryptophan sources on amino acids availability to the brain and mood in healthy volunteers. Psychopharmacology (Berl) 201: 107-114.
    • (2008) Psychopharmacology (Berl) , vol.201 , pp. 107-114
    • Markus, C.R.1    Firk, C.2    Gerhardt, C.3    Kloek, J.4    Smolders, G.F.5
  • 42
    • 67649206975 scopus 로고    scopus 로고
    • Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression; A meta-analysis
    • Risch N, Herrell R, Lehner T, Liang KY, Eaves L, Hoh J et al (2009). Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression; a meta-analysis. JAMA 301: 2462-2471.
    • (2009) JAMA , vol.301 , pp. 2462-2471
    • Risch, N.1    Herrell, R.2    Lehner, T.3    Liang, K.Y.4    Eaves, L.5    Hoh, J.6
  • 43
    • 33748559016 scopus 로고    scopus 로고
    • Serotonin transporter polymorphism mediates vulnerability to loss of incentive motivation following acute tryptophan depletion
    • DOI 10.1038/sj.npp.1301055, PII 1301055
    • Roiser JP, Blackwell AD, Cools R, Clark L, Rubinsztein DC, Robbins TW et al (2006). Serotonin transporter polymorphism mediates vulnerability to loss of incentive motivation following acute tryptophan depletion. Neuropsychopharmacology 31: 2264-2272. (Pubitemid 44413205)
    • (2006) Neuropsychopharmacology , vol.31 , Issue.10 , pp. 2264-2272
    • Roiser, J.P.1    Blackwell, A.D.2    Cools, R.3    Clark, L.4    Rubinsztein, D.C.5    Robbins, T.W.6    Sahakian, B.J.7
  • 44
    • 33947653784 scopus 로고    scopus 로고
    • Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans: A meta-analysis of monoamine depletion studies
    • DOI 10.1038/sj.mp.4001949, PII 4001949
    • Ruhe HG, Mason NS, Schene AH (2007). Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans: a meta-analysis of monoamine depletion studies. Mol Psychiatry 12: 331-359. (Pubitemid 46496835)
    • (2007) Molecular Psychiatry , vol.12 , Issue.4 , pp. 331-359
    • Ruhe, H.G.1    Mason, N.S.2    Schene, A.H.3
  • 46
    • 19444380511 scopus 로고    scopus 로고
    • Cognitive reactivity and vulnerability: Empirical evaluation of construct activation and cognitive diatheses in unipolar depression
    • DOI 10.1016/j.cpr.2005.01.005, PII S0272735805000073
    • Scher CD, Ingram RE, Segal ZV (2005). Cognitive reactivity and vulnerability: empirical evaluation of construct activation and cognitive diatheses in unipolar depression. Psychol Rev 25: 487-510. (Pubitemid 40725816)
    • (2005) Clinical Psychology Review , vol.25 , Issue.4 , pp. 487-510
    • Scher, C.D.1    Ingram, R.E.2    Segal, Z.V.3
  • 47
    • 33847257284 scopus 로고    scopus 로고
    • Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with selective serotonin reuptake inhibitor efficacy in depressed patients
    • DOI 10.1038/sj.mp.4001926, PII 4001926
    • Serretti A, Kato M, De Ronchi D, Kinoshita T (2007). Meta-analysis of serotonin transporter gene promotor polymorphism (5-HTTLPR) association with selective serotonin reuptake inhibitor efficacy in depressed patients. Mol Psychiatry 12: 247-257. (Pubitemid 46328503)
    • (2007) Molecular Psychiatry , vol.12 , Issue.3 , pp. 247-257
    • Serretti, A.1    Kato, M.2    De Ronchi, D.3    Kinoshita, T.4
  • 49
    • 33846089075 scopus 로고    scopus 로고
    • Increased Amygdala and Decreased Dorsolateral Prefrontal BOLD Responses in Unipolar Depression: Related and Independent Features
    • DOI 10.1016/j.biopsych.2006.05.048, PII S0006322306007931
    • Siegle GJ, Thompson W, Carter CS, Steinhauer SR, Thase ME (2007). Increased amygdala and decreased dorsolateral prefron-tal BOLD responses in unipolar depression: related and independent features. Biol Psychiatry 61: 198-209. (Pubitemid 46072788)
    • (2007) Biological Psychiatry , vol.61 , Issue.2 , pp. 198-209
    • Siegle, G.J.1    Thompson, W.2    Carter, C.S.3    Steinhauer, S.R.4    Thase, M.E.5
  • 50
    • 38349150151 scopus 로고    scopus 로고
    • The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: Review and methodological analysis
    • Uher R, McGuffin P (2008). The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis. Mol Psychiatry 13: 131-146.
    • (2008) Mol Psychiatry , vol.13 , pp. 131-146
    • Uher, R.1    McGuffin, P.2
  • 52
    • 0014965699 scopus 로고
    • 5-Hydroxyindoleacetic acid levels in the cerebrospinal fluid of depressive patients treated with probenecid
    • van Praag HM, Korf J, Puite J (1970). 5-Hydroxyindoleacetic acid levels in the cerebrospinal fluid of depressive patients treated with probenecid. Nature 225: 1259-1260.
    • (1970) Nature , vol.225 , pp. 1259-1260
    • Van Praag, H.M.1    Korf, J.2    Puite, J.3
  • 53
    • 34548188825 scopus 로고    scopus 로고
    • Interactive Effects of Sex and 5-HTTLPR on Mood and Impulsivity During Tryptophan Depletion in Healthy People
    • DOI 10.1016/j.biopsych.2007.02.012, PII S0006322307001473
    • Walderhaug E, Magnusson A, Neumeister A, Lappalainen J, Lunde H, Refsum H et al (2007). Interactive effects of sex and 5-HTTLPR on mood and impulsivity during tryptophan depletion in healthy people. Biol Psychiatry 62: 593-599. (Pubitemid 47314384)
    • (2007) Biological Psychiatry , vol.62 , Issue.6 , pp. 593-599
    • Walderhaug, E.1    Magnusson, A.2    Neumeister, A.3    Lappalainen, J.4    Lunde, H.5    Refsum, H.6    Landro, N.I.7
  • 54
    • 0024023344 scopus 로고
    • Development and validation of brief measures of positive and negative affect: The PANAS scales
    • Watson D, Clark LA, Tellegen A (1988). Development and validation of brief measures of positive and negative affect: the PANAS scales. J Pers Soc Psychol 54: 1063-1070.
    • (1988) J Pers Soc Psychol , vol.54 , pp. 1063-1070
    • Watson, D.1    Clark, L.A.2    Tellegen, A.3
  • 55
    • 33644614818 scopus 로고    scopus 로고
    • Simultaneous genotyping of four functional loci of human SLC6A4, with a reappraisal of 5-HTTLPR and rs25531
    • Wendland JR, Martin BJ, Kruse MR, Lesch KP, Murphy DL (2006). Simultaneous genotyping of four functional loci of human SLC6A4, with a reappraisal of 5-HTTLPR and rs25531. Mol Psychiatry 11: 224-226.
    • (2006) Mol Psychiatry , vol.11 , pp. 224-226
    • Wendland, J.R.1    Martin, B.J.2    Kruse, M.R.3    Lesch, K.P.4    Murphy, D.L.5
  • 57
    • 0033036573 scopus 로고    scopus 로고
    • Effects of acute tryptophan depletion on plasma and cerebrospinal fluid tryptophan and 5-hydroxyindoleacetic acid in normal volunteers
    • DOI 10.1046/j.1471-4159.1999.721641.x
    • Williams WA, Shoaf SE, Hommer D, Rawlings R, Linnoila M (1999). Effects of acute tryptophan depletion on plasma and cerebrospinal fluid tryptophan and 5-hydroxyindoleacetic acid in normal volunteers. J Neurochem 72: 1641-1647. (Pubitemid 29140839)
    • (1999) Journal of Neurochemistry , vol.72 , Issue.4 , pp. 1641-1647
    • Williams, W.A.1    Shoaf, S.E.2    Hommer, D.3    Rawlings, R.4    Linnoila, M.5
  • 58
    • 85047697355 scopus 로고    scopus 로고
    • Association of a triallelic seroton in transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression
    • DOI 10.1176/appi.ajp.163.9.1588
    • Zalsman G, Huang YY, Oquendo MA, Burke AK, Hu XZ, Brent DA et al (2006). Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression. Am J Psychiatry 163: 1588-1593. (Pubitemid 44465760)
    • (2006) American Journal of Psychiatry , vol.163 , Issue.9 , pp. 1588-1593
    • Zalsman, G.1    Huang, Y.-Y.2    Oquendo, M.A.3    Burke, A.K.4    Hu, X.-Z.5    Brent, D.A.6    Ellis, S.P.7    Goldman, D.8    Mann, J.J.9


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