Graft survival and cytokine production profile after limbal transplantation in the experimental mouse model

Transplant Immunology

Volumn 24, Issue 3, 2011, Pages 189-194

  LenÁová, Anna ^a,b   Pokorná, Kateřina ^a,c   Zajícová, Alena ^a   Krulová, Magdaléna ^a,c   Filipec, Martin ^b   HoláÍ, Vladimír ^a,c  

^a INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^b Eye Clinic Lexum   (Czech Republic)

^c CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Anti CD4 treatment; Cytokine response; Graft survival; Limbal transplantation

Indexed keywords

CD4 ANTIBODY; GAMMA INTERFERON; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4;

ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CORNEA DISEASE; CYTOKINE PRODUCTION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GRAFT REJECTION; GRAFT SURVIVAL; LIMBAL STEM CELL TRANSPLANTATION; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; SURVIVAL TIME; TH1 CELL; TH2 CELL; XENOGRAFT; XENOTRANSPLANTATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD4; ANTIGENS, CD8; EYE; GRAFT REJECTION; GRAFT SURVIVAL; INTERFERON-GAMMA; INTERLEUKINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MODELS, ANIMAL; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, INBRED LEW; STEM CELL TRANSPLANTATION; TH1 CELLS; TH2 CELLS; TRANSPLANTATION, HETEROLOGOUS; TRANSPLANTATION, HOMOLOGOUS;

EID: 79951512279     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trim.2010.11.005     Document Type: Article

References (31)

1. Tseng S.C. Regulation and clinical implications of corneal epithelial stem cells. Mol Biol Rep 1996, 23:47-58.
2. Daniels J.T., Dart J.K., Tuft S.J., Khaw P.T. Corneal stem cells in review. Wound Repair Regen 2001, 9:483-494.
3. Huang A.J., Tseng S.C. Corneal epithelial wound healing in the absence of limbal epithelium. Investig Ophthalmol Vis Sci 1991, 32:96-105.
4. Majo F., Rochat A., Nicolas M., Jaoude G.A., Barrandon Y. Oligopotent stem cells are distributed throughout the mammalian ocular surface. Nature 2008, 456:250-254.
5. Chang C.-Y., Green C.R., McGhee C.N.J., Sherwin T. Acute wound healing in the human central corneal epithelium appears to be independent of limbal stem cell influence. Investig Ophthalmol Vis Sci 2008, 49:5279-5286.
6. Dua H.S., Miri A., Alomar T., Yeung A.M., Said D.G. The role of limbal stem cells in corneal epithelial maintenance: testing the dogma. Ophthalmology 2009, 116:856-863.
7. Tan D.T., Ficker L.A., Buckley R.J. Limbal transplantation. Ophthalmology 1996, 103:29-36.
8. Pellegrini G., Traverso C.E., Franzi A.T., Zingirian M., Canceda R., De Luca M. Long term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium. Lancet 1997, 349:990-993.
9. Dua H.S., Azuara-Blanco A. Allo-limbal transplantation in patients with limbal stem cell deficiency. Br J Ophthalmol 1999, 83:414-419.
10. Tsubota K., Satake Y., Kaido M., Shinozaki N., Shimmura S., Bissen-Miyajima H., et al. Treatment of severe ocular surface disorders with corneal epithelial stem-cell transplantation. N Engl J Med 1999, 340:1697-1703.
11. Holland E.J. Epithelial transplantation for the management of severe ocular surface disease. Trans Am Ophthalmol Soc 1996, 94:677-743.
12. Cauchi P.A., Ang G.S., Azuara-Blanco A., Burr J.M. A systematic literature review of surgical interventions for limbal stem cell deficiency in humans. Am J Ophthalmol 2008, 146:251-259.
13. Thoft R.A., Sugar J. Graft failure in keratoepithelioplasty. Cornea 1993, 12:362-365.
14. Daya S.M., Bell R.W., Habib N.E., Powel-Richards A., Dua H.S. Clinic and pathologic findings in human keratolimbal allograft rejection. Cornea 2000, 19:443-450.
15. Mills R.A., Coster D.J., Williams K.A. Effect of immunosuppression on outcome measures in a model of rat limbal transplantation. Investig Ophthalmol Vis Sci 2002, 43:647-655.
16. Maruyama K., Yamada J., Sano Y., Kinoshida S. Th2-biased immune system promotion of allogeneic corneal epithelial cell survival after orthotopic limbal transplantation. Investig Ophthalmol Vis Sci 2003, 44:4736-4741.
17. Swift G.J., Aggarwal R.K., Davis G.J., Coster D.J., Williams K.A. Survival of rabbit limbal stem cell allografts. Transplantation 1996, 62:568-574.
18. Holan V., Haskova Z., Filipec M. Transplantation immunity and tolerance in the eye. Rejection and acceptance of orthotopic corneal allografts in mice. Transplantation 1996, 62:1050-1054.
19. Vítova A., Filipec M., Zajicova A., Krulova M., Holan V. Prevention of corneal allograft rejection in a mouse model of high-risk recipients. Br J Ophthalmol 2004, 88:1338-1342.
20. Pindjakova J., Vitova A., Krulova M., Zajicova A., Filipec M., Holan V. Corneal rat-to mouse xenotransplantation and the effects of anti-CD4 or anti-CD8 treatment on cytokine and nitric oxide production. Transpl Int 2005, 18:854-862.
21. Krulova M., Zajicova A., Fric J., Holan V. Alloantigen-induced, T-cell-dependent production of nitric oxide by macrophages infiltrating skin allografts in mice. Transpl Int 2002, 15:108-116.
22. Masaki Y., Hirasawa A., Okuyama S., Tsujimoto G., Iwaya M., Li X.K., et al. Microchimerism and heart allograft acceptance. Transplant Proc 1995, 27:148-150.
23. Dialynas D.P., Wilde D.B., Marrack P., Pierres A., Wall K.A., Havran W., et al. Characterization of the murine antigenic determinant designated L3T4a, recognized by monoclonal antibody GK1.5: expression of L3T4a by functional T cell clones appears to correlate primarily with class II MHC antigen-reactivity. Immunol Rev 1983, 74:29-56.
24. Gottlieb P.D., Marshak-Rothstein A., Auditore-Hargreaves K. Construction and properties of new Lyt-congeneic strains and anti-Lyt-2.2 and anti-Lyt-3.1 monoclonal antibodies. Immunogenetics 1980, 10:545-552.
25. Gillette T.E., Chandler J.W., Greiner J.V. Langherhans cells of the ocular surface. Ophthalmology 1982, 89:700-711.
26. Haskova Z., Filipec M., Holan V. The significance of gender incompatibility in donors and recipients and the role of minor histocompatibility antigens in corneal transplantation. Cesk Slov Oftalmol 1997, 53:128-135.
27. Keijser S., de Keizer R.J., Prins F.A., Tanke H.J., van Rooijen N., Vrensen G.F., et al. A new model for limbal transplantation using E-GFP for follow-up of transplant survival. Exp Eye Res 2006, 83:188-195.
28. Strestikova P., Plskova J., Filipec M., Farghali H. FK 506 and aminoguanidine suppress iNOS induction in orthotopic corneal allografts and prolong graft survival in mice. Nitric Oxide 2003, 9:111-117.
29. Siegers T.P., Broersma L., van Rooijen N., Hooymans J.M., van Rij G., van der Gaag R. Macrophages play a role in the early phase of corneal allograft rejection in rats. Transplantation 2004, 77:1641-1646.
30. Wallgren A.C., Karlsson-Parra A., Korsgren O. The main infiltrating cell in xenograft rejection is a CD4+ macrophage and not a T lymphocyte. Transplantation 1995, 60:594-601.
31. He Y.G., Ross J., Niederkorn J.Y. Promotion of murine orthotopic corneal allograft survival by systemic administration of anti-CD4 monoclonal antibody. Investig Ophthalmol Vis Sci 1991, 32:2723-2727.