Negative regulation of RPE cell attachment by carbohydrate-dependent cell surface binding of galectin-3 and inhibition of the ERK-MAPK pathway

Biochimie

Volumn 93, Issue 3, 2011, Pages 477-488

  Alge Priglinger, Claudia S ^a,b,c   André, Sabine ^a   Schoeffl, Harald ^c   Kampik, Anselm ^a   Strauss, Rupert W ^b   Kernt, Marcus ^a   Gabius, Hans Joachim ^a   Priglinger, Siegfried G ^a,b,c  

^a UNIVERSITY OF MUNICH   (Germany)

^b KEPLER UNIVERSITY HOSPITAL   (Austria)

^c Zet Life Science Laboratorium   (Austria)

Author keywords

Attachment; Cytoskeleton; Galectin 3; MAPK; Proliferative; Retinal pigment epithelium; Vitreoretinopathy

Indexed keywords

CARBOHYDRATE; CROSS LINKING REAGENT; FIBRONECTIN; GALACTOSE; GALECTIN 3; GLYCAN; MITOGEN ACTIVATED PROTEIN KINASE;

ADULT; AGED; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL ADHESION; CELL DEDIFFERENTIATION; CELL SPREADING; CELL SURFACE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROFILAMENT; PIGMENT EPITHELIUM; PROLIFERATIVE RETINOPATHY; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

AGED; BINDING, COMPETITIVE; CARBOHYDRATE METABOLISM; CELL ADHESION; CELL SHAPE; CELL SURVIVAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GALECTIN 1; GALECTIN 3; GENE EXPRESSION REGULATION; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MICROFILAMENTS; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN BINDING; RETINAL PIGMENT EPITHELIUM;

EID: 79951511139     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2010.10.021     Document Type: Article

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