Membrane organization and dynamics of the serotonin1A receptor in live cells

Journal of Neurochemistry

Volumn 116, Issue 5, 2011, Pages 726-733

  Saxena, Roopali ^a   Chattopadhyay, Amitabha ^a  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

cholesterol; detergent insolubility; dynamic confinement; FRAP; G protein coupled receptor; serotonin1A receptors

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GREEN FLUORESCENT PROTEIN; SEROTONIN 1A RECEPTOR;

ANXIETY DISORDER; CHOLESTEROL METABOLISM; DEPRESSION; DIFFUSION; FLUORESCENCE MICROSCOPY; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; HUMAN; IMMUNOBLOTTING; LIGAND BINDING; MEMBRANE BIOLOGY; MEMBRANE PERMEABILITY; NEUROPSYCHIATRY; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN LOCALIZATION; REVIEW; SOLUBILITY;

ANIMALS; CELL MEMBRANE; DIFFUSION; HUMANS; LUMINESCENT AGENTS; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; NONLINEAR DYNAMICS; RECEPTOR, SEROTONIN, 5-HT1A;

EID: 79851481133     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.07037.x     Document Type: Review

References (57)

1. Baker A.-M., Sauliàíre A., Gaibelet G., Lagane B., Mazàíres S., Fourage M., Bachelerie F., Salomé L., Lopez A., and, Dumas F., (2007) CD4 interacts constitutively with multiple CCR5 at the plasma membrane of living cells. A fluorescence recovery after photobleaching at variable radii approach. J. Biol. Chem. 282, 35163-35168. (Pubitemid 350232458)
2. Banerjee P., Joo J. B., Buse J. T., and, Dawson G., (1995) Differential solubilization of lipids along with membrane proteins by different classes of detergents. Chem. Phys. Lipids 77, 65-78.
3. Brown D. A., and, Rose J. K., (1992) Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. Cell 68, 533-544.
4. Cézanne L., Lecat S., Lagane B., Millot C., Vollmer J. Y., Matthes H., Galzi J. L., and, Lopez A., (2004) Dynamic confinement of NK2 receptors in the plasma membrane. Improved FRAP analysis and biological relevance. J. Biol. Chem. 279, 45057-45067. (Pubitemid 39430920)
5. Chamberlain L. H., (2004) Detergents as tools for the purification and classification of lipid rafts. FEBS Lett. 559, 1-5. (Pubitemid 38186694)
6. 2-adrenergic G protein-coupled receptor. Science 318, 1258-1265. (Pubitemid 350172884)
7. Edidin M., (1992) Patches, posts and fences: proteins and plasma membrane domains. Trends Cell Biol. 2, 376-380.
8. Edidin M., (2001) Shrinking patches and slippery rafts: scales of domains in the plasma membrane. Trends Cell Biol. 11, 492-496. (Pubitemid 33079142)
9. Edidin M., and, Stroynowski I., (1991) Differences between the lateral organization of conventional and inositol phospholipid-anchored membrane proteins. A further definition of micrometer scale membrane domains. J. Cell Biol. 112, 1143-1150. (Pubitemid 21909656)
10. 1A receptor correlates with receptor signaling. Biophys. J. 95, 451-463.
11. Gardier A. M., (2009) Mutant mouse models and antidepressant drug research: focus on serotonin and brain-derived neurotrophic factor. Behav. Pharmacol. 20, 18-32.
12. van der Goot F. G., and, Harder T., (2001) Raft membrane domains: from a liquid-ordered membrane phase to a site of pathogen attack. Semin. Immunol. 13, 89-97. (Pubitemid 32382330)
13. Groves J. T., and, Kuriyan J., (2010) Molecular mechanisms in signal transduction at the membrane. Nat. Struct. Mol. Biol. 17, 659-665.
14. Hansen G. H., Niels-Christiansen L., Thorsen E., Immerdal L., and, Danielsen E. M., (2000) Cholesterol depletion of enterocytes: effect on the golgi complex and apical membrane trafficking. J. Biol. Chem. 275, 5136-5142. (Pubitemid 30108916)
15. Hao M., Mukherjee S., and, Maxfield F. R., (2001) Cholesterol depletion induces large scale domain segregation in living cell membranes. Proc. Natl Acad. Sci. USA 98, 13072-13077. (Pubitemid 33051319)
16. Harder T., Scheiffele P., Verkade P., and, Simons K., (1998) Lipid domain structure of the plasma membrane revealed by patching of membrane components. J. Cell Biol. 141, 929-942. (Pubitemid 28243961)
17. Heerklotz H., (2002) Triton promotes domain formation in lipid raft mixtures. Biophys. J. 83, 2693-2701. (Pubitemid 35265761)
18. Heilker R., Wolff M., Tautermann C. S., and, Bieler M., (2009) G-protein-coupled receptor-focused drug discovery using a target class platform approach. Drug Discov. Today 14, 231-240.
19. Hooper N. M., (1999) Detergent-insoluble glycosphingolipid/cholesterol- rich membrane domains, lipid rafts and caveolae. Mol. Membr. Biol. 16, 145-156. (Pubitemid 29308814)
20. Hur E.-M., and, Kim K. T., (2002) G protein-coupled receptor signalling and cross-talk: achieving rapidity and specificity. Cell. Signal. 14, 397-405. (Pubitemid 34214844)
21. Jacobson K., Mouritsen O. G., and, Anderson R. G. W., (2007) Lipid rafts: at a crossroad between cell biology and physics. Nat. Cell Biol. 9, 7-14. (Pubitemid 46024188)
22. 1A receptor. FEBS Lett. 576, 455-460. (Pubitemid 39388645)
23. 1A receptor monitored by detergent insolubility using GFP fluorescence. Mol. Membr. Biol. 22, 539-547. (Pubitemid 43030909)
24. 1A receptor monitored by a detergent-free approach. Cell. Mol. Neurobiol. 27, 463-474. (Pubitemid 46763891)
25. Lagerholm B. C., Weinreb G. E., Jacobson K., and, Thompson N. L., (2005) Detecting microdomains in intact cell membranes. Annu. Rev. Phys. Chem. 56, 309-336. (Pubitemid 41156881)
26. Lin S. H., and, Civelli O., (2004) Orphan G protein-coupled receptors: targets for new therapeutic interventions. Ann. Med. 36, 204-214. (Pubitemid 38680197)
27. Mukherjee S., and, Maxfield F. R., (2004) Membrane domains. Annu. Rev. Cell Dev. Biol. 20, 839-866. (Pubitemid 39488660)
28. Munro S., (2003) Lipid rafts: elusive or illusive? Cell 115, 377-388. (Pubitemid 37456801)
29. Ostrom R. S., and, Insel P. A., (2004) The evolving role of lipid rafts and caveolae in G protein-coupled receptor signaling: implications for molecular pharmacology. Br. J. Pharmacol. 143, 235-245. (Pubitemid 39315143)
30. Paila Y. D., and, Chattopadhyay A., (2010) Membrane cholesterol in the function and organization of G-protein coupled receptors. Subcell. Biochem. 51, 439-466.
31. Paila Y. D., Tiwari S., and, Chattopadhyay A., (2009) Are specific nonannular cholesterol binding sites present in G-protein coupled receptors? Biochim. Biophys. Acta 1788, 295-302.
32. Pediconi M. F., Gallegos C. E., De Los Santos E. B., and, Barrantes F. J., (2004) Metabolic cholesterol depletion hinders cell-surface trafficking of the nicotinic acetylcholine receptor. Neuroscience 128, 239-249. (Pubitemid 39200472)
33. Peters R., (1988) Lateral mobility of proteins and lipids in the red cell membrane and the activation of adenylate cyclase by beta-adrenergic receptors. FEBS Lett. 234, 1-7.
34. Pierce K. L., Premont R. T., and, Lefkowitz R. J., (2002) Seven-transmembrane receptors. Nat. Rev. Mol. Cell Biol. 3, 639-650. (Pubitemid 34987785)
35. Pike L. J., and, Casey L., (2002) Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking. Biochemistry 41, 10315-10322. (Pubitemid 34856457)
36. Pucadyil T. J., and, Chattopadhyay A., (2004) Exploring detergent insolubility in bovine hippocampal membranes: a critical assessment of the requirement for cholesterol. Biochim. Biophys. Acta 1661, 9-17. (Pubitemid 38201567)
37. Pucadyil T. J., and, Chattopadhyay A., (2006) Role of cholesterol in the function and organization of G-protein coupled receptors. Prog. Lipid Res. 45, 295-333. (Pubitemid 43818130)
38. Pucadyil T. J., and, Chattopadhyay A., (2007a) Cholesterol: a potential therapeutic target in Leishmania infection? Trends Parasitol. 23, 49-53. (Pubitemid 46176741)
39. 1A receptor in the plasma membrane of living cells. Biochim. Biophys. Acta 1768, 655-668. (Pubitemid 46275612)
40. 1A receptor tagged to yellow fluorescent protein. Biochemistry 43, 15852-15862. (Pubitemid 39665084)
41. 1A receptor: a representative member of the serotonin receptor family. Cell. Mol. Neurobiol. 25, 553-580. (Pubitemid 41186261)
42. 1A receptor in lipid microdomains depends on its palmitoylation and is involved in receptor-mediated signaling. Mol. Pharmacol. 72, 502-513. (Pubitemid 47347285)
43. Rivas M. G., and, Gennaro A. M., (2003) Detergent resistant domains in erythrocyte membranes survive after cell cholesterol depletion: an EPR spin label study. Chem. Phys. Lipids 122, 165-169. (Pubitemid 36207522)
44. Romanenko V., Fang Y., Travis A., and, Levitan I., (2004) Partitioning of Kir2.1 channels into Triton-insoluble membrane domains is independent of the level of cellular cholesterol. J. Gen. Physiol. 124, 15a.
45. Rosenbaum D. M., Rasmussen S. G. F., and, Kobilka B. K., (2009) The structure and function of G-protein-coupled receptors. Nature 459, 356-363.
46. Salomé L., Cazeils J. L., Lopez A., and, Tocanne J. F., (1998) Characterization of membrane domains by FRAP experiments at variable observation areas. Eur. Biophys. J. 27, 391-402. (Pubitemid 28319749)
47. Sauliàíre-Nzeh A. N., Millot C., Corbani M., Mazàíres S., Lopez A., and, Salomé L., (2010) Agonist-selective dynamic compartmentalization of human mu opioid receptor as revealed by resolutive FRAP analysis. J. Biol. Chem. 285, 14514-14520.
48. Schlyer S., and, Horuk R., (2006) I want a new drug: G-protein-coupled receptors in drug development. Drug Discov. Today 11, 481-493.
49. Schroeder R. J., Ahmed S. N., Zhu Y., London E., and, Brown D. A., (1998) Cholesterol and sphingolipid enhance the Triton X-100 insolubility of glycosylphosphatidylinositol-anchored proteins by promoting the formation of detergent-insoluble ordered membrane domains. J. Biol. Chem. 273, 1150-1157. (Pubitemid 28049216)
50. 1A receptors. Biochemistry 49, 5426-5435.
51. Simons K., and, Toomre D., (2000) Lipid rafts and signal transduction. Nat. Rev. Mol. Cell Biol. 1, 31-39.
52. Subtil A., Gaidarov I., Kobylarz K., Lampson M. A., Keen J. H., and, McGraw T. E., (1999) Acute cholesterol depletion inhibits clathrin-coated pit budding. Proc. Natl Acad. Sci. USA 96, 6775-6780. (Pubitemid 29274959)
53. Veatch S. L., and, Keller S. L., (2003) Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol. Biophys. J. 85, 3074-3083. (Pubitemid 37345795)
54. Xu X., and, London E., (2000) The effect of sterol structure on membrane lipid domains reveals how cholesterol can induce lipid domain formation. Biochemistry 39, 843-849. (Pubitemid 30075310)
55. Yechiel E., and, Edidin M., (1987) Micrometer-scale domains in fibroblast plasma membranes. J. Cell Biol. 105, 755-760. (Pubitemid 18043838)
56. Zhang Y., DeVries M. E., and, Skolnick J., (2006) Structure modeling of all identified G protein-coupled receptors in the human genome. PLoS Comput. Biol. 2, 88-99.
57. 1A binding sites. Brain Res. Mol. Brain Res. 69, 186-201. (Pubitemid 29253811)