Ruta graveolens extract induces DNA damage pathways and blocks Akt activation to inhibit cancer cell proliferation and survival

Anticancer Research

Volumn 31, Issue 1, 2011, Pages 233-241

  Fadlalla, Khalda ^a   Watson, Angela ^a   Yehualaeshet, Teshome ^a   Turner, Timothy ^a   Samuel, Temesgen ^a  

^a TUSKEGEE UNIVERSITY   (United States)

Author keywords

Akt; Apoptosis; Bioactivity; Medicinal herb; p53 pathway; Ruta graveolens

Indexed keywords

CYCLIN B1; DNA; DNA BINDING PROTEIN; PROTEIN 53BP1; PROTEIN GAMMA H2AX; PROTEIN KINASE B; PROTEIN P53; RUTA GRAVEOLENS EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CLONOGENESIS; COLON CANCER; DNA DAMAGE; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN LOCALIZATION;

APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CASPASE 3; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DNA DAMAGE; DNA, NEOPLASM; ENZYME ACTIVATION; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MALE; PLANT EXTRACTS; PLANTS, MEDICINAL; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; RUTA; TUMOR CELLS, CULTURED; TUMOR STEM CELL ASSAY;

EID: 79851479069     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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