Evidence that bergapten, independently of its photoactivation, enhances p53 gene expression and induces apoptosis in human breast cancer cells

Current Cancer Drug Targets

Volumn 9, Issue 4, 2009, Pages 469-481

  Panno, M L ^a   Giordano, F ^a   Palma, M G ^a   Bartella, V ^a   Rago, V ^a   Maggiolini, M ^a   Sisci, D ^a   Lanzino, M ^a   De Amicis, F ^a   Ando S ^a  

^a UNIVERSITY OF CALABRIA   (Italy)

Author keywords

Apoptosis; Bergapten; MAPK; MCF 7; NFY; p21; p53; SKBR 3

Indexed keywords

BERGAPTEN; CASPASE 8; CASPASE 9; CYCLIN DEPENDENT KINASE INHIBITOR; DNA; ESTROGEN RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P53; SOMATOMEDIN C;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL GROWTH; CELL SURVIVAL; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; P53 GENE; PHOTOACTIVATION; PROMOTER REGION; STAINING; TRANSACTIVATION; ULTRAVIOLET RADIATION;

APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P21; ESTRADIOL; FEMALE; GENE EXPRESSION; HUMANS; INSULIN-LIKE GROWTH FACTOR I; METHOXSALEN; NEOPLASMS, HORMONE-DEPENDENT; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOTOSENSITIZING AGENTS; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 67649307356     PISSN: 15680096     EISSN: None     Source Type: Journal    
DOI: 10.2174/156800909788486786     Document Type: Article

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