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Volumn 91, Issue 2, 2011, Pages 77-84

Functional effects of genetic polymorphisms in the N-acetyltransferase 1 coding and 3′ untranslated regions

Author keywords

Acetylator genotype; Acetylator phenotype; Arylamines; Haplotypes; N acetyltransferase 1 polymorphisms

Indexed keywords

ACYLTRANSFERASE; MESSENGER RNA; N ACETYLTRANSFERASE 1; NUCLEOTIDE; UNCLASSIFIED DRUG;

EID: 79851475806     PISSN: 15420752     EISSN: 15420760     Source Type: Journal    
DOI: 10.1002/bdra.20763     Document Type: Article
Times cited : (19)

References (48)
  • 1
    • 34547661669 scopus 로고    scopus 로고
    • Hair dye use, meat intake, and tobacco exposure and presence of carcinogen-DNA adducts in exfoliated breast ductal epithelial cells
    • Ambrosone CB, Abrams SM, Gorlewska-Roberts K, et al. 2007. Hair dye use, meat intake, and tobacco exposure and presence of carcinogen-DNA adducts in exfoliated breast ductal epithelial cells. Arch Biochem Biophys 464: 169-175.
    • (2007) Arch Biochem Biophys , vol.464 , pp. 169-175
    • Ambrosone, C.B.1    Abrams, S.M.2    Gorlewska-Roberts, K.3
  • 2
    • 0029163025 scopus 로고
    • Polyadenylation polymorphism in the acetyltransferase 1 gene (NAT1) increases risk of colorectal cancer
    • Bell DA, Stephens EA, Castranio T, et al. 1995. Polyadenylation polymorphism in the acetyltransferase 1 gene (NAT1) increases risk of colorectal cancer. Cancer Res 55: 3537-3542.
    • (1995) Cancer Res , vol.55 , pp. 3537-3542
    • Bell, D.A.1    Stephens, E.A.2    Castranio, T.3
  • 3
    • 0345240943 scopus 로고    scopus 로고
    • Correlation between genotype and phenotype of the human arylamine N-acetyltransferase type 1 (NAT1)
    • Bruhn C, Brockmoller J, Cascorbi I, et al. 1999. Correlation between genotype and phenotype of the human arylamine N-acetyltransferase type 1 (NAT1). Biochem Pharmacol 58: 1759-1764.
    • (1999) Biochem Pharmacol , vol.58 , pp. 1759-1764
    • Bruhn, C.1    Brockmoller, J.2    Cascorbi, I.3
  • 4
    • 33748593396 scopus 로고    scopus 로고
    • Risk of limb deficiency defects associated with NAT1, NAT2, GSTT1, GSTM1, and NOS3 genetic variants, maternal smoking, and vitamin supplement intake
    • Carmichael SL, Shaw GM, Yang W, et al. 2006. Risk of limb deficiency defects associated with NAT1, NAT2, GSTT1, GSTM1, and NOS3 genetic variants, maternal smoking, and vitamin supplement intake Am J Med Genet A 140: 1915-1922.
    • (2006) Am J Med Genet A , vol.140 , pp. 1915-1922
    • Carmichael, S.L.1    Shaw, G.M.2    Yang, W.3
  • 5
    • 33646527381 scopus 로고    scopus 로고
    • The influence of various genotypes on the metabolic activity of NAT2 in a Chinese population
    • Chen B, Zhang WX, Cai WM., et al. 2006. The influence of various genotypes on the metabolic activity of NAT2 in a Chinese population. Eur J Clin Pharmacol 62: 355-359.
    • (2006) Eur J Clin Pharmacol , vol.62 , pp. 355-359
    • Chen, B.1    Zhang, W.X.2    Cai, W.M.3
  • 6
    • 0032146178 scopus 로고    scopus 로고
    • A prospective study of N-acetyltransferase genotype, red meat intake, and risk of colorectal cancer
    • Chen J, Stampfer MJ, Hough HL, et al. 1998. A prospective study of N-acetyltransferase genotype, red meat intake, and risk of colorectal cancer. Cancer Res 58: 3307-3311.
    • (1998) Cancer Res , vol.58 , pp. 3307-3311
    • Chen, J.1    Stampfer, M.J.2    Hough, H.L.3
  • 7
    • 0343627972 scopus 로고    scopus 로고
    • Characterization of naturally occurring and recombinant human N-acetyltransferase variants encoded by NAT1
    • de Leon JH, Vatsis KP, Weber WW., et al. 2000. Characterization of naturally occurring and recombinant human N-acetyltransferase variants encoded by NAT1. Mol Pharmacol 58: 288-299.
    • (2000) Mol Pharmacol , vol.58 , pp. 288-299
    • de Leon, J.H.1    Vatsis, K.P.2    Weber, W.W.3
  • 8
    • 77954913118 scopus 로고    scopus 로고
    • Codominant expression of N-acetylation and O-acetylation activities catalyzed by N-acetyltransferase 2 in human hepatocytes
    • Doll MA, Zang Y, Moeller T, et al. 2010. Codominant expression of N-acetylation and O-acetylation activities catalyzed by N-acetyltransferase 2 in human hepatocytes. J Pharmacol Exp Ther 334: 540-544.
    • (2010) J Pharmacol Exp Ther , vol.334 , pp. 540-544
    • Doll, M.A.1    Zang, Y.2    Moeller, T.3
  • 9
    • 42949146499 scopus 로고    scopus 로고
    • Confirmation of the role of N-acetyltransferase 2 in teratogen-induced cleft palate using transgenics and knockouts
    • Erickson RP, Cao W, Acuna DK, et al. 2008. Confirmation of the role of N-acetyltransferase 2 in teratogen-induced cleft palate using transgenics and knockouts. Mol Reprod Dev 75: 1071-1076.
    • (2008) Mol Reprod Dev , vol.75 , pp. 1071-1076
    • Erickson, R.P.1    Cao, W.2    Acuna, D.K.3
  • 10
    • 0034893017 scopus 로고    scopus 로고
    • Functional characterization of nucleotide polymorphisms in the coding region of N-acetyltransferase 1
    • Fretland AJ, Doll MA, Leff MA, et al. 2001. Functional characterization of nucleotide polymorphisms in the coding region of N-acetyltransferase 1. Pharmacogenetics 11: 511-520.
    • (2001) Pharmacogenetics , vol.11 , pp. 511-520
    • Fretland, A.J.1    Doll, M.A.2    Leff, M.A.3
  • 11
    • 0036952798 scopus 로고    scopus 로고
    • Effect of nucleotide substitutions in N-acetyltransferase-1 on N-acetylation (deactivation) and O-acetylation (activation) of arylamine carcinogens: implications for cancer predisposition
    • Fretland AJ, Doll MA, Zhu Y, et al. 2002. Effect of nucleotide substitutions in N-acetyltransferase-1 on N-acetylation (deactivation) and O-acetylation (activation) of arylamine carcinogens: implications for cancer predisposition. Cancer Detect Prev 26: 10-14.
    • (2002) Cancer Detect Prev , vol.26 , pp. 10-14
    • Fretland, A.J.1    Doll, M.A.2    Zhu, Y.3
  • 12
    • 0037356860 scopus 로고    scopus 로고
    • Permanent hair dyes and bladder cancer: risk modification by cytochrome P4501A2 and N-acetyltransferases 1 and 2
    • Gago-Dominguez M, Bell DA, Watson MA, et al. 2003. Permanent hair dyes and bladder cancer: risk modification by cytochrome P4501A2 and N-acetyltransferases 1 and 2. Carcinogenesis 24: 483-489.
    • (2003) Carcinogenesis , vol.24 , pp. 483-489
    • Gago-Dominguez, M.1    Bell, D.A.2    Watson, M.A.3
  • 13
    • 34447301791 scopus 로고    scopus 로고
    • Development of lung cancer before the age of 50: the role of xenobiotic metabolizing genes
    • Gemignani F, Landi S, Szeszenia-Dabrowska N, et al. 2007. Development of lung cancer before the age of 50: the role of xenobiotic metabolizing genes. Carcinogenesis 28: 1287-1293.
    • (2007) Carcinogenesis , vol.28 , pp. 1287-1293
    • Gemignani, F.1    Landi, S.2    Szeszenia-Dabrowska, N.3
  • 14
    • 0031011356 scopus 로고    scopus 로고
    • Human acetyltransferase polymorphisms
    • Grant DM, Hughes NC, Janezic SA, et al. 1997. Human acetyltransferase polymorphisms. Mutat Res 376: 61-70.
    • (1997) Mutat Res , vol.376 , pp. 61-70
    • Grant, D.M.1    Hughes, N.C.2    Janezic, S.A.3
  • 15
    • 0023812845 scopus 로고
    • Acetylator genotype and arylamine-induced carcinogenesis
    • Hein DW. 1988. Acetylator genotype and arylamine-induced carcinogenesis. Biochim Biophys Acta 948: 37-66.
    • (1988) Biochim Biophys Acta , vol.948 , pp. 37-66
    • Hein, D.W.1
  • 16
    • 67649243788 scopus 로고    scopus 로고
    • N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine
    • Hein DW. 2009. N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine. Expert Opin Drug Metab Toxicol 5: 353-366.
    • (2009) Expert Opin Drug Metab Toxicol , vol.5 , pp. 353-366
    • Hein, D.W.1
  • 17
    • 0036391671 scopus 로고    scopus 로고
    • Association of prostate cancer with rapid N-acetyltransferase 1 (NAT110) in combination with slow N-acetyltransferase 2 acetylator genotypes in a pilot case-control study
    • Hein DW, Leff MA, Ishibe N, et al. 2002. Association of prostate cancer with rapid N-acetyltransferase 1 (NAT110) in combination with slow N-acetyltransferase 2 acetylator genotypes in a pilot case-control study. Environ Mol Mutagen 40: 161-167.
    • (2002) Environ Mol Mutagen , vol.40 , pp. 161-167
    • Hein, D.W.1    Leff, M.A.2    Ishibe, N.3
  • 18
    • 0031932385 scopus 로고    scopus 로고
    • Identification and characterization of variant alleles of human acetyltransferase NAT1 with defective function using p-aminosalicylate as an in-vivo and in-vitro probe
    • Hughes NC, Janezic SA, McQueen KL, et al. 1998. Identification and characterization of variant alleles of human acetyltransferase NAT1 with defective function using p-aminosalicylate as an in-vivo and in-vitro probe. Pharmacogenetics 8: 55-66.
    • (1998) Pharmacogenetics , vol.8 , pp. 55-66
    • Hughes, N.C.1    Janezic, S.A.2    McQueen, K.L.3
  • 19
    • 34548059291 scopus 로고    scopus 로고
    • Functional analysis of the human N-acetyltransferase 1 major promoter: quantitation of tissue expression and identification of critical sequence elements
    • Husain A, Zhang X, Doll MA, et al. 2007. Functional analysis of the human N-acetyltransferase 1 major promoter: quantitation of tissue expression and identification of critical sequence elements. Drug Metab Dispos 35: 1649-1656.
    • (2007) Drug Metab Dispos , vol.35 , pp. 1649-1656
    • Husain, A.1    Zhang, X.2    Doll, M.A.3
  • 20
    • 18344386384 scopus 로고    scopus 로고
    • Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas
    • Ishibe N, Sinha R, Hein DW, et al. 2002. Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas. Pharmacogenetics 12: 145-150.
    • (2002) Pharmacogenetics , vol.12 , pp. 145-150
    • Ishibe, N.1    Sinha, R.2    Hein, D.W.3
  • 21
    • 22944446755 scopus 로고    scopus 로고
    • The NAT1 C1095A polymorphism, maternal multivitamin use and smoking, and the risk of spina bifida
    • Jensen LE, Hoess K, Whitehead AS, et al. 2005. The NAT1 C1095A polymorphism, maternal multivitamin use and smoking, and the risk of spina bifida. Birth Defects Res A Clin Mol Teratol 73: 512-516.
    • (2005) Birth Defects Res A Clin Mol Teratol , vol.73 , pp. 512-516
    • Jensen, L.E.1    Hoess, K.2    Whitehead, A.S.3
  • 22
    • 38849128680 scopus 로고    scopus 로고
    • Haplotype of N-acetyltransferase 1 and 2 and risk of pancreatic cancer
    • Jiao L, Doll MA, Hein DW, et al. 2007. Haplotype of N-acetyltransferase 1 and 2 and risk of pancreatic cancer. Cancer Epidemiol Biomarkers Prev 16: 2379-2386.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 2379-2386
    • Jiao, L.1    Doll, M.A.2    Hein, D.W.3
  • 23
    • 0032810707 scopus 로고    scopus 로고
    • Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) genes and risk of urothelial transitional cell carcinoma among Japanese
    • Katoh T, Inatomi H, Yang M, et al. 1999. Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) genes and risk of urothelial transitional cell carcinoma among Japanese. Pharmacogenetics 9: 401-404.
    • (1999) Pharmacogenetics , vol.9 , pp. 401-404
    • Katoh, T.1    Inatomi, H.2    Yang, M.3
  • 24
    • 74149093116 scopus 로고    scopus 로고
    • Genetic variation in N-acetyltransferases 1 and 2, cigarette smoking, and risk of non-Hodgkin lymphoma
    • Kilfoy BA, Zheng T, Lan Q, et al. 2010. Genetic variation in N-acetyltransferases 1 and 2, cigarette smoking, and risk of non-Hodgkin lymphoma. Cancer Causes Control 21: 127-133.
    • (2010) Cancer Causes Control , vol.21 , pp. 127-133
    • Kilfoy, B.A.1    Zheng, T.2    Lan, Q.3
  • 25
    • 2442502651 scopus 로고    scopus 로고
    • Maternal smoking and the risk of orofacial clefts: Susceptibility with NAT1 and NAT2 polymorphisms
    • Lammer EJ, Shaw GM, Iovannisci DM, et al. 2004a. Maternal smoking and the risk of orofacial clefts: Susceptibility with NAT1 and NAT2 polymorphisms. Epidemiology 15: 150-156.
    • (2004) Epidemiology , vol.15 , pp. 150-156
    • Lammer, E.J.1    Shaw, G.M.2    Iovannisci, D.M.3
  • 26
    • 10044281543 scopus 로고    scopus 로고
    • Periconceptional multivitamin intake during early pregnancy, genetic variation of acetyl-N-transferase 1 (NAT1), and risk for orofacial clefts
    • Lammer EJ, Shaw GM, Iovannisci DM, et al. 2004b. Periconceptional multivitamin intake during early pregnancy, genetic variation of acetyl-N-transferase 1 (NAT1), and risk for orofacial clefts. Birth Defects Res A Clin Mol Teratol 70: 846-852.
    • (2004) Birth Defects Res A Clin Mol Teratol , vol.70 , pp. 846-852
    • Lammer, E.J.1    Shaw, G.M.2    Iovannisci, D.M.3
  • 27
    • 0038645511 scopus 로고    scopus 로고
    • N-acetyltransferase (NAT1, NAT2) and glutathione S-transferase (GSTM1, GSTT1) polymorphisms in breast cancer
    • Lee KM, Park SK, Kim SU, et al. 2003. N-acetyltransferase (NAT1, NAT2) and glutathione S-transferase (GSTM1, GSTT1) polymorphisms in breast cancer Cancer Lett 196: 179-186.
    • (2003) Cancer Lett , vol.196 , pp. 179-186
    • Lee, K.M.1    Park, S.K.2    Kim, S.U.3
  • 28
    • 29744455626 scopus 로고    scopus 로고
    • Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer
    • Li D, Jiao L, Li Y, et al. 2006. Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer. Carcinogenesis 27: 103-111.
    • (2006) Carcinogenesis , vol.27 , pp. 103-111
    • Li, D.1    Jiao, L.2    Li, Y.3
  • 29
    • 33645457048 scopus 로고    scopus 로고
    • Effect of NAT1 and NAT2 genetic polymorphisms on colorectal cancer risk associated with exposure to tobacco smoke and meat consumption
    • Lilla C, Verla-Tebit E, Risch A, et al. 2006. Effect of NAT1 and NAT2 genetic polymorphisms on colorectal cancer risk associated with exposure to tobacco smoke and meat consumption. Cancer Epidemiol Biomarkers Prev 15: 99-107.
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 99-107
    • Lilla, C.1    Verla-Tebit, E.2    Risch, A.3
  • 30
    • 67651091328 scopus 로고    scopus 로고
    • Effects of NAT2 polymorphism on SASP pharmacokinetics in Chinese population
    • Ma JJ, Liu CG, Li JH, et al. 2009. Effects of NAT2 polymorphism on SASP pharmacokinetics in Chinese population. Clin Chim Acta 407: 30-35.
    • (2009) Clin Chim Acta , vol.407 , pp. 30-35
    • Ma, J.J.1    Liu, C.G.2    Li, J.H.3
  • 31
    • 0031903725 scopus 로고    scopus 로고
    • Cigarette smoking, N-acetyltransferases 1 and 2, and breast cancer risk
    • Millikan RC, Pittman GS, Newman B, et al. 1998. Cigarette smoking, N-acetyltransferases 1 and 2, and breast cancer risk. Cancer Epidemiol Biomarkers Prev 7: 371-378.
    • (1998) Cancer Epidemiol Biomarkers Prev , vol.7 , pp. 371-378
    • Millikan, R.C.1    Pittman, G.S.2    Newman, B.3
  • 32
    • 34548071866 scopus 로고    scopus 로고
    • Hair dye use, genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma
    • Morton LM, Bernstein L, Wang SS, et al. 2007. Hair dye use, genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma. Carcinogenesis 28: 1759-1764.
    • (2007) Carcinogenesis , vol.28 , pp. 1759-1764
    • Morton, L.M.1    Bernstein, L.2    Wang, S.S.3
  • 33
    • 33746216637 scopus 로고    scopus 로고
    • Genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2) and risk of non-Hodgkin lymphoma
    • Morton LM, Schenk M, Hein DW, et al. 2006. Genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2) and risk of non-Hodgkin lymphoma. Pharmacogenet Genomics 16: 537-545.
    • (2006) Pharmacogenet Genomics , vol.16 , pp. 537-545
    • Morton, L.M.1    Schenk, M.2    Hein, D.W.3
  • 35
    • 34548721074 scopus 로고    scopus 로고
    • Joint effects of the N-acetyltransferase 1 and 2 (NAT1 and NAT2) genes and smoking on bladder carcinogenesis: a literature-based systematic HuGE review and evidence synthesis
    • Sanderson S, Salanti G, Higgins J, et al. 2007. Joint effects of the N-acetyltransferase 1 and 2 (NAT1 and NAT2) genes and smoking on bladder carcinogenesis: a literature-based systematic HuGE review and evidence synthesis. Am J Epidemiol 166: 741-751.
    • (2007) Am J Epidemiol , vol.166 , pp. 741-751
    • Sanderson, S.1    Salanti, G.2    Higgins, J.3
  • 36
    • 41849129433 scopus 로고    scopus 로고
    • Review on genetic variants and maternal smoking in the etiology of oral clefts and other birth defects
    • Shi M, Wehby GL, Murray JC, et al. 2008. Review on genetic variants and maternal smoking in the etiology of oral clefts and other birth defects. Birth Defects Res C Embryo Today 84: 16-29.
    • (2008) Birth Defects Res C Embryo Today , vol.84 , pp. 16-29
    • Shi, M.1    Wehby, G.L.2    Murray, J.C.3
  • 37
    • 39449127911 scopus 로고    scopus 로고
    • Meat intake, heterocyclic amine exposure, and metabolizing enzyme polymorphisms in relation to colorectal polyp risk
    • Shin A, Shrubsole MJ, Rice JM, et al. 2008. Meat intake, heterocyclic amine exposure, and metabolizing enzyme polymorphisms in relation to colorectal polyp risk. Cancer Epidemiol Biomarkers Prev 17: 320-329.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 320-329
    • Shin, A.1    Shrubsole, M.J.2    Rice, J.M.3
  • 38
    • 0033759301 scopus 로고    scopus 로고
    • An update on genetic, structural and functional studies of arylamine N-acetyltransferases in eucaryotes and procaryotes
    • Sim E, Payton M, Noble M, et al. 2000. An update on genetic, structural and functional studies of arylamine N-acetyltransferases in eucaryotes and procaryotes. Hum Mol Genet 9: 2435-2441.
    • (2000) Hum Mol Genet , vol.9 , pp. 2435-2441
    • Sim, E.1    Payton, M.2    Noble, M.3
  • 39
    • 0034639999 scopus 로고    scopus 로고
    • Expression of arylamine N-acetyltransferases in pre-term placentas and in human pre-implantation embryos
    • Smelt VA, Upton A, Adjaye J, et al. 2000. Expression of arylamine N-acetyltransferases in pre-term placentas and in human pre-implantation embryos. Hum Mol Genet 9: 1101-1107.
    • (2000) Hum Mol Genet , vol.9 , pp. 1101-1107
    • Smelt, V.A.1    Upton, A.2    Adjaye, J.3
  • 40
    • 46949090331 scopus 로고    scopus 로고
    • Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer
    • Suzuki H, Morris JS, Li Y, et al. 2008. Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer. Carcinogenesis 29: 1184-1191.
    • (2008) Carcinogenesis , vol.29 , pp. 1184-1191
    • Suzuki, H.1    Morris, J.S.2    Li, Y.3
  • 41
    • 0032529236 scopus 로고    scopus 로고
    • The role of N-acetylation polymorphisms in smoking-associated bladder cancer: evidence of a gene-gene-exposure three-way interaction
    • Taylor JA, Umbach DM, Stephens E, et al. 1998. The role of N-acetylation polymorphisms in smoking-associated bladder cancer: evidence of a gene-gene-exposure three-way interaction. Cancer Res 58: 3603-3610.
    • (1998) Cancer Res , vol.58 , pp. 3603-3610
    • Taylor, J.A.1    Umbach, D.M.2    Stephens, E.3
  • 42
    • 35649014879 scopus 로고    scopus 로고
    • Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism
    • Wakefield L, Cornish V, Long H, et al. 2007. Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism. Biochem Biophys Res Commun 364: 556-560.
    • (2007) Biochem Biophys Res Commun , vol.364 , pp. 556-560
    • Wakefield, L.1    Cornish, V.2    Long, H.3
  • 43
    • 38949133904 scopus 로고    scopus 로고
    • Structure-function analyses of single nucleotide polymorphisms in human N-acetyltransferase 1
    • Walraven JM, Trent JO, Hein DW., et al. 2008. Structure-function analyses of single nucleotide polymorphisms in human N-acetyltransferase 1. Drug Metab Rev 40: 169-184.
    • (2008) Drug Metab Rev , vol.40 , pp. 169-184
    • Walraven, J.M.1    Trent, J.O.2    Hein, D.W.3
  • 44
    • 17744376645 scopus 로고    scopus 로고
    • Relevance of N-acetyltransferase 1 and 2 (NAT1, NAT2) genetic polymorphisms in non-small cell lung cancer susceptibility
    • Wikman H, Thiel S, Jager B, et al. 2001. Relevance of N-acetyltransferase 1 and 2 (NAT1, NAT2) genetic polymorphisms in non-small cell lung cancer susceptibility. Pharmacogenetics 11: 157-168.
    • (2001) Pharmacogenetics , vol.11 , pp. 157-168
    • Wikman, H.1    Thiel, S.2    Jager, B.3
  • 45
    • 9244240756 scopus 로고    scopus 로고
    • The T341C (Ile114Thr) polymorphism of N-acetyltransferase 2 yields slow acetylator phenotype by enhanced protein degradation
    • Zang Y, Zhao S, Doll MA, et al. 2004. The T341C (Ile114Thr) polymorphism of N-acetyltransferase 2 yields slow acetylator phenotype by enhanced protein degradation. Pharmacogenetics 14: 717-723.
    • (2004) Pharmacogenetics , vol.14 , pp. 717-723
    • Zang, Y.1    Zhao, S.2    Doll, M.A.3
  • 46
    • 33746800293 scopus 로고    scopus 로고
    • N-Acetyltransferase-1 gene polymorphisms and correlation between genotype and its activity in a central Chinese Han population
    • Zhangwei X, Jianming X, Qiao M, et al. 2006. N-Acetyltransferase-1 gene polymorphisms and correlation between genotype and its activity in a central Chinese Han population. Clin Chim Acta 371: 85-91.
    • (2006) Clin Chim Acta , vol.371 , pp. 85-91
    • Zhangwei, X.1    Jianming, X.2    Qiao, M.3
  • 47
    • 0032958158 scopus 로고    scopus 로고
    • N-acetyltransferase 1 genetic polymorphism, cigarette smoking, well-done meat intake, and breast cancer risk
    • Zheng W, Deitz AC, Campbell DR, et al. 1999. N-acetyltransferase 1 genetic polymorphism, cigarette smoking, well-done meat intake, and breast cancer risk. Cancer Epidemiol Biomarkers Prev 8: 233-239.
    • (1999) Cancer Epidemiol Biomarkers Prev , vol.8 , pp. 233-239
    • Zheng, W.1    Deitz, A.C.2    Campbell, D.R.3
  • 48
    • 52749085010 scopus 로고    scopus 로고
    • Functional effects of single nucleotide polymorphisms in the coding region of human N-acetyltransferase 1
    • Zhu Y, Hein DW. 2008. Functional effects of single nucleotide polymorphisms in the coding region of human N-acetyltransferase 1. Pharmacogenomics J 8: 339-348.
    • (2008) Pharmacogenomics J , vol.8 , pp. 339-348
    • Zhu, Y.1    Hein, D.W.2


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