Non-destructive characterization of microdamage in cortical bone using low field pulsed NMR

Journal of the Mechanical Behavior of Biomedical Materials

Volumn 4, Issue 3, 2011, Pages 383-391

  Nicolella, Daniel P ^a   Ni, Qingwen ^a   Chan, Kwai S ^a  

^a SOUTHWEST RESEARCH INSTITUTE   (United States)

Author keywords

Bone fatigue; Microdamage; NMR T2 relaxation time data; Property degradation

Indexed keywords

AMBIENT TEMPERATURES; ANALYTICAL MODEL; CEMENT LINE; CHARACTERIZATION TECHNIQUES; CORTICAL BONE; CYCLIC LOADINGS; DAMAGE ACCUMULATION; EXPERIMENTAL MEASUREMENTS; FOUR-POINT BENDING; HUMAN CORTICAL BONE; INTERSTITIAL TISSUES; LOW FIELD; MICRO-CRACK DENSITY; MICRODAMAGE; MODULUS DEGRADATION; NMR MEASUREMENTS; NON DESTRUCTIVE; NONDESTRUCTIVE CHARACTERIZATION; PROPERTY DEGRADATION; PULSED NMR; RELAXATION TECHNIQUES; SERIAL SECTIONING; SPIN-SPIN; T2 RELAXATION;

BONE; CYCLIC LOADS; DEGRADATION; FATIGUE OF MATERIALS; LOADING; MATHEMATICAL MODELS; MICROCRACKS; NUCLEAR MAGNETIC RESONANCE; POPULATION DISTRIBUTION; POROSITY; RELAXATION TIME; RESONANCE; SIZE DISTRIBUTION;

BONE CEMENT;

ARTICLE; BIOMECHANICS; BONE INJURY; CONTROLLED STUDY; CORTICAL BONE; DEGRADATION; HISTOLOGY; HUMAN; HUMAN TISSUE; INTERSTITIUM; NUCLEAR MAGNETIC RESONANCE; POROSITY; PRIORITY JOURNAL;

BIOMECHANICS; ELASTIC MODULUS; FEMUR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MECHANICAL PROCESSES; MODELS, BIOLOGICAL; POROSITY;

EID: 79751533016     PISSN: 17516161     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmbbm.2010.11.007     Document Type: Article

References (45)

1. Bentolila V., Boyce T.M., Fyhrie D.P., Drumb R., Skerry T.M., Schaffler M.B. Intracortical remodeling in adult rat long bones after fatigue loading. Bone 1998, 23:275-281.
2. Bowers M.C., Ehrlich R., Howard J.J., Kenyon W.E. Determination of porosity types from NMR data and their relationship to porosity types derived from thin section. Journal of Petroleum Science and Engineering 1995, 13:1-14.
3. Boyce T.M., Fyhre D.P., Glotkowski M.C., Radin E.L., Schaffler M.B. Damage type and strain mode associations in human compact bone bending fatigue. Journal of Orthopedic Research 1998, 16:322-329.
4. Budiansky B., O'Connell R.J. Elastic moduli of a cracked solid. International Journal of Solids and Structures 1976, 12:81-97.
5. Burr D.B. Targeted and nontargeted remodeling. Bone 2002, 30:2-4.
6. Burr D.B., Forwood M.R., Fyhrie D.P., Martin R.B., Schaffler M.B., Turner C.H. Bone microdamage and skeletal fragility in osteoporotic and stress fractures. Journal of Bone and Mineral Research 1997, 12:6-15.
7. Burr D.B., Hooser M. Alterations to the en bloc basic fuchsin staining protocol for the demonstration of microdamage produced in vivo. Bone 1995, 17:431-433.
8. Burr D.B., Martin R.B., Schaffler M.B., Radin E.L. Bone remodeling in response to in vivo fatigue microdamage. Journal of Biomechanics 1985, 18:189-200.
9. Burr D.B., Turner C.H., Naick P., Forwood M.R., Ambrosius W., Hasan M.S., Pidaparti R. Does microdamage accumulation affect the mechanical properties of bone?. Journal of Biomechanics 1998, 31:337-345.
10. Burr D.B., Turner C.H., Naick P., Forwood M.R., Pidaparti R. En bloc staining of bone under load does not improve dye diffusion into microcracks. Journal of Biomechanics 1998, 31:285-288.
11. Cardoso L., Herman B.C., Verborgt O., Laudier D., Majeska R.J., Schaffler M.B. Osteocyte apoptosis controls activation of intracortical resorption in response to bone fatigue. Journal of Bone and Mineral Research 2009, 24:597-605.
12. Carter D.R., Hayes W.C. Compact bone fatigue damage-I. Residual strength and stiffness. Journal of Biomechanics 1977, 10:325-337.
13. Feng X.Q. On estimation methods for effective moduli of microcracked solids. Archive of Applied Mechanics 2001, 71:537-548.
14. Frost H.M. Precense of microscopic cracks in-vivo in bone. Henry Ford Medical Bulletin 1960, 8:27-35.
15. Gallegos D.P., Munn K., Smith D.M., Stermer D.L. A NMR technique for the analysis of pore structure: application to materials with well-defined pore structure. Journal of Colloid and Interface Science 1987, 119:127-140.
16. Glaves C.L., Davis P.J., Gallegos D.P., Smith D.M. Pore structure analysis of coals via low-field spin-lattice relaxation measurements. Energy & Fuels 1988, 2:662-668.
17. Glaves C.L., Smith D.M. Membrane pore structure analysis via NMR spin-lattice relaxation experiments. Journal of Membrane Science 1989, 46:167-184.
18. Handa S., Tomiha S., Kose K., Haishi T. In vivo assessment of the trabecular bone microstructure of the distal radius using a compact MRI system. Magnetic Resonance in Medical Sciences: MRMS: An Official Journal of Japan Society of Magnetic Resonance in Medicine 2009, 8:39-42.
19. Herman B.C., Cardoso L., Majeska R.J., Jepsen K.J., Schaffler M.B. Activation of bone remodeling after fatigue: differential response to linear microcracks and diffuse damage. Bone 2010.
20. Hoshaw S.J., Cody D.D., Saad A.M., Fyhrie D.P. Decrease in canine proximal femoral ultimate strength and stiffness due to fatigue damage. Journal of Biomechanics 1997, 30:323-329.
21. Hsieh Y.F., Silva M.J. In vivo fatigue loading of the rat ulna induces both bone formation and resorption and leads to time-related changes in bone mechanical properties and density. Journal of Orthopaedic Research 2002, 20:764-771.
22. Kenyon W.E. Petrophysical principles of applications of NMR logging. Logic and Analysis 1997, 38:21-40.
23. Kleinberg R.L., Farooqui S.A., Horsfield M.A. T1/T2 ratio and frequency dependence of NMR relaxation in porous sedimentary rocks. Journal of Colloid and Interfance Science 1993, 158:95-198.
24. Krug R., Burghardt A.J., Majumdar S., Link T.M. High-resolution imaging techniques for the assessment of osteoporosis. Radiologic Clinics of North America 2010, 48:601-621.
25. Li C.Q., Magland J.F., Rajapakse C.S., Guo X.E., Zhang X.H., Vasilic B., Wehrli F.W. Implications of resolution and noise for in vivo micro-MRI of trabecular bone. Medical Physics 2008, 35:5584-5594.
26. Liaw H.K., Kulkarni R., Chen S., Watson A.T. Characterization of fluid distributions in porous media by NMR techniques. AIChE Journal 1996, 42:538-546.
27. Magland J.F., Wald M.J., Wehrli F.W. Spin-echo micro-MRI of trabecular bone using improved 3D fast large-angle spin-echo (FLASE). Magnetic Resonance in Medicine 2009, 61:1114-1121.
28. Martin R.B. Is all cortical bone remodeling initiated by microdamage?. Bone 2002, 30:8-13.
29. Mori S., Burr D.B. Increased intracortical remodelling following fatigue damage. Bone 1993, 14:103-109.
30. Mulkern R.V., Meng J., Oshio K., Guttmann C.R., Jaramillo D. Bone marrow characterization in the lumbar spine with inner volume spectroscopic CPMG imaging studies. Journal of Magnetic Resonance Imaging 1994, 4:585-589.
31. Ni Q.W., King J.D., Wang X.D. The characterization of human compact bone structure changes by low-field nuclear magnetic resonance. Measurement Science and Technology 2004, 15:58-66.
32. Ni Q.W., Nicolella D.P. The characterization of human cortical bone microdamage by nuclear magnetic resonance. Measurement Science and Technology 2005, 16:659-668.
33. Ni Q., Nyman J.S., Wang X., De Los Santos A., Nicolella D.P. Assessment of water distribution changes in human cortical bone by nuclear magnetic resonance. Measurement Science and Technology 2007, 18:715-723.
34. Norman T.L., Wang Z. Microdamage of human cortical bone: incidence and morphology in long bones. Bone 1997, 20:375-379.
35. Norman T.L., Yeni Y.N., Brown C.U., Wang Z. Influence of microdamage on fracture toughness of the human femur and tibia. Bone 1998, 23:303-306.
36. O'Brien F.J., Taylor D., Dickson G.R., Lee T.C. Visualisation of three-dimensional microcracks in compact bone. Journal of Anatomy 2000, 197:413-420.
37. Pattin C.A., Caler W.E., Carter D.R. Cyclic mechanical property degradation during fatigue loading of cortical bone. Journal of Biomechanics 1996, 29:69-79.
38. Schaffler M.B., Jepsen K.J. Fatigue and repair in bone. International Journal of Fatigue 2000, 22:839-846.
39. Schaffler M.B., Radin E.L., Burr D.B. Mechanical and morphological effects of strain rate on fatigue of compact bone. Bone 1989, 10:207-214.
40. Smith, D.M., Glaves, C.L., Gallegos, D.P., 1988. Pore structure characterization of catalyst supports via low field NMR. Preprints Symposia, 33. pp. 618-622.
41. Traber F., Block W., Layer G., Braucker G., Gieseke J., Kretzer S., Hasan I., Schild H.H. Determination of 1H relaxation times of water in human bone marrow by fat-suppressed turbo spin echo in comparison to MR spectroscopic methods. Journal of Magnetic Resonance Imaging 1996, 6:541-548.
42. Wald M.J., Magland J.F., Rajapakse C.S., Wehrli F.W. Structural and mechanical parameters of trabecular bone estimated from in vivo high-resolution magnetic resonance images at 3 Tesla field strength. Journal of Magnetic Resonance Imaging 2010, 31:1157-1168.
43. Wang X., Ni Q. Determination of cortical bone porosity and pore size distribution using a low field pulsed NMR approach. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society 2003, 21:312-319.
44. Wehrli F.W., Ladinsky G.A., Jones C., Benito M., Magland J., Vasilic B., Popescu A.M., Zemel B., Cucchiara A.J., Wright A.C., Song H.K., Sana P.K., Peachey H., Snyder P.J. In vivo magnetic resonance detects rapid remodeling changes in the topology of the trabecular bone network after menopause and the protective effect of estradiol. Journal of Bone and Mineral Research 2008, 23:730-740.
45. oMRI-based finite element and morphological analyses of tibial trabecular bone in eugonadal and hypogonadal men before and after testosterone treatment. Journal of Bone and Mineral Research 2008, 23:1426-1434.