Influence of microdamage on fracture toughness of the human femur and tibia

Bone

Volumn 23, Issue 3, 1998, Pages 303-306

  Norman, Timothy L ^a   Yeni, Y N ^a   Brown, C U ^a   Wang, Z ^a  

^a WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Bone fragility; Cortical bone; Fracture; Fracture toughness; Microdamage

Indexed keywords

ADULT; AGED; ARTICLE; BONE INJURY; BONE STRENGTH; CADAVER; CLINICAL ARTICLE; CONTROLLED STUDY; CORTICAL BONE; FEMALE; FEMUR FRACTURE; HUMAN; HUMAN TISSUE; MALE; TIBIA FRACTURE;

AGED; AGED, 80 AND OVER; AGING; BONE DENSITY; FEMALE; FEMORAL FRACTURES; HUMANS; MALE; MIDDLE AGED; TIBIAL FRACTURES;

EID: 0031716031     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(98)00103-3     Document Type: Article

References (37)

1. Anderson, T. L. Fracture Mechanics: Fundamentals and Applications. Boca Raton, FL; CRC; 1991.
2. Bradley, W. L. Understanding the translation of neat resin toughness into delamination toughness in composites. Key Eng Mater 37:161-198; 1989.
3. Brown, C. U., Yeni, Y. N., and Norman, T. L. Fracture toughness is dependent on bone location - a study of the femoral neck, femoral shaft and tibial shaft. J Biomed Mater Res. In press.
4. Burr, D. B., Forwood, M. R., Fyhrie, D. P., Martin, R. B., Schaffler, M. B., and Turner, C. H. Bone microdamage and skeletal fragility in osteoporotic and stress fractures. J Bone Miner Res 12:6-15; 1997.
5. Burr, D. B. and Stafford, T. Validity of the bulk-staining technique to separate artifactual from in vivo bone microdamage. Clin Orthop Relat Res 260:305-308; 1994.
6. Burr, D. B., Turner, C. H., Naick, P., Forwood, M. R., and Pidaparti, R. M. V. Does microdamage accumulation affect the mechanical properties of bone? In: Transactions of the 41st Annual Meeting of the Orthopedic Research Society, Orlando, FL, 1995; 127.
7. Carter, D. R. and Hayes, W. C. Compact bone fatigue damage - II. Residual strength and stiffness. J Biomech 10:323-337; 1977.
8. Carter, D. R. and Hayes, W. C. Compact bone fatigue damage: A microscopic examination. Clin Orthop 127:265-274; 1977.
9. Consensus Development Conference: Prophylaxis and treatment of osteoporosis. Am J Med 90:107-110; 1991.
10. Fazzalari, N. L., Forwood, M. R., Smith, K., Manthey, B. A., and Herreen, P. Assessment of cancellous bone quality in severe osteoarthrosis: Bone mineral density, mechanics, and microdamage. Bone 22:381-388; 1998.
11. Forwood, M. R. and Parker, A. W. Microdamage in response to repetitive torsional loading in the rat tibia. Calcif Tissue Int 45:47-53; 1989.
12. Freeman, M. A. R., Todd, R. C., and Pirie, C. J. The role of fatigue in the pathogenesis of senile femoral neck fractures. J Bone Jt Surg 56-B:698; 1974.
13. Frost, H. M. Presence of microscopic cracks in vivo in bone. Henry Ford Hosp Bull 8:25-35; 1960.
14. Frost, H. M. Bone microdamage: Factors that impair its repair. In: Uhtoff, H. D., Ed. Current Concepts of Bone Fragility. Berlin: Springer; 1985; 123-148.
15. Giladi, M., Milgrom, C., Simkiu, A., and Danon, Y. Stress fractures: Identifiable risk factors. Am J Sports Med 19:647-652; 1991.
16. Heaney, R. P. The natural history of vertebral osteoporosis. Is low bone mass an epiphenomenon? Bone 13(Suppl. 2):S23-S26; 1992.
17. Hui, S., Slemenda, C. W., and Johnston, C. C. Age and bone mass as predictors of fracture in a prospective study. J Clin Invest 81:1804-1809; 1988.
18. Li, G., Zhang, S., Chen, G., Chen, H., and Wang, A. Radiographic and histologic analyses of stress fracture in rabbit tibias. Am J Sports Med 13:285-294; 1985.
19. Martin, R. B. Mathematical model for repair of fatigue damage and stress fracture in osteonal bone. J Orthopaed Res 13:309-316; 1995.
20. Matheon, G. O., Clement, D. B., Mckenzie, D. C., Taunton, J. F., Lloyd-Smith, D. R., and Macintyre, J. G. Stress fractures in athletes: A study of 320 cases. Am J Sports Med 15:46-59; 1987.
21. Melton, L. J. and Wahner, H. W. Defining osteoporosis. Calcif Tissue Int 45:263-264.
22. Mori, S., Harruff, R., Ambrosius, W., and Burr, D. B. Trabecular bone volume and microdamage accumulation in the femoral heads of women with and without femoral neck fractures. Bone 21:521-526; 1997.
23. Norman, T. L. and Wang, Z. Microdamage of human cortical bone: Incidence and morphology in long bones. Bone 20:375-379; 1997.
24. Norman, T. L., Nivargikar, S., and Burr, D. B. Resistance to crack growth in human bone is greater in shear than intension. J Biomech 29:1023-1031; 1996.
25. Schaffler, M. B., Choi, K., and Milgram, C. Aging and matrix microdamage accumulation in human compact bone. Bone 17:521-525; 1995.
26. Schaffler, M. B., Boyce, T. M., and Fyhrie, D. P. Tissue and matrix failure modes in human compact bone during tensile fatigue. Trans Orthop Res Soc 21:57; 1995.
27. Schaffler, M. B., Boyce, T. M., Lundin-Cannon, K. D., Milgrom, C., and Fyhrie, D. P. Age related architectural changes and microdamage accumulation in the human femoral neck cortex. In: Transactions of the 41st Annual Meeting of the Orthopedic Research Society, Orlando, FL; 1995; 549.
28. Schaffler, M. B., Pitchford, W. C., Choi, K., and Riddle, J. M. Examination of compact bone microdamage using back scattered electron microscopy. Bone 15:483-488; 1994.
29. Schaffler, M. B., Radin, E. L., and Burr, D. B. Mechanical and morphological effects of strain rate on fatigue of compact bone. Bone 10:207-214; 1989.
30. Sherman, S., Heaney, R. P., Parfitt, A. M., Hadley, E. C., and Dutta, C. NIA workshop on Aging and Bone Quality, Bethesda, MD, Sept. 3-4, 1992. Calcif Tissue Int 53(Suppl. 1):S1-S180; 1993.
31. Tschantz, P. and Rutishauser, E. La surchage mechanique de l'os vivant. Ann Anat Pathol 12:223-248; 1967.
32. Vashishth, D., Behiri, J. C., and Bonfield, W. Crack growth resistance in cortical bone: Concept of microcrack toughening. J Biomech 30:763-769; 1997.
33. Wright, T. M. and Hayes, W. C. Tensile testing of bone over a wide range of strain rates: Effects of strain rate, micro structure and density. Med Biol Eng 14:671-680; 1976.
34. Yeni, Y. N., Brown, C. U., Wang, Z., and Norman, T. L. The influence of bone morphology on fracture toughness of the human femur and tibia. Bone 21:453-459; 1997.
35. Yeni, Y. N., Brown, C. U., Wang, Z., and Norman, T. L. Influence of bone composition and apparent density on fracture toughness of the human femur and tibia. Bone 22:79-84; 1998.
36. Yeni, Y. N. and Norman, T. L., Hydroxyapatite crystal perfection influences the fracture toughness of human cortical bone. In: Transactions of the 44th Annual Meeting of the Orthopaedic Research Society; 1998; 961.
37. Zioupos, P. and Currey, J. D. Changes in the stiffness, strength, and toughness of human cortical bone with age. Bone 22:57-66; 1998.