Vitamin D deficiency promotes growth of MCF-7 human breast cancer in a rodent model of osteosclerotic bone metastasis

Bone

Volumn 47, Issue 4, 2010, Pages 795-803

  Ooi, Li Laine ^a   Zheng, Yu ^a   Zhou, Hong ^a   Trivedi, Trupti ^a   Conigrave, Arthur D ^a   Seibel, Markus J ^a   Dunstan, Colin R ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Bone formation; Bone resorption; Breast cancer; Metastasis; Osteosclerosis; Vitamin D deficiency

Indexed keywords

CALCITRIOL; OSTEOPROTEGERIN; OXYGENASE; PARATHYROID HORMONE; STEROID 24 HYDROXYLASE; UNCLASSIFIED DRUG; VITAMIN D; VITAMIN D RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE METASTASIS; BONE TURNOVER; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CANCER TRANSPLANTATION; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; DIETARY INTAKE; DISEASE ASSOCIATION; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOLYSIS; OSTEOSCLEROSIS; PARATHYROID HORMONE BLOOD LEVEL; SIGNAL TRANSDUCTION; TIBIA; TUMOR LOCALIZATION; TUMOR VOLUME; TUMOR XENOGRAFT; VITAMIN D DEFICIENCY; VITAMIN D METABOLISM; X RAY ANALYSIS;

ACID PHOSPHATASE; ADIPOSE TISSUE; ANIMALS; APOPTOSIS; BONE AND BONES; BONE NEOPLASMS; BONE REMODELING; BREAST NEOPLASMS; CALCITRIOL; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; ISOENZYMES; MICE; OSTEOLYSIS; OSTEOSCLEROSIS; TUMOR BURDEN; VITAMIN D DEFICIENCY; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77956409606     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2010.07.012     Document Type: Article

References (54)

1. Grant W.B., Garland C.F. The association of solar ultraviolet B (UVB) with reducing risk of cancer: multifactorial ecologic analysis of geographic variation in age-adjusted cancer mortality rates. Anticancer Res 2006, 26:2687-2699.
2. Grant W.B., Mohr S.B. Ecological studies of ultraviolet B, vitamin D and cancer since 2000. Ann Epidemiol 2009, 19:446-454.
3. Morris H.A. Vitamin D: a hormone for all seasons-how much is enough?. Clin Biochem Rev 2005, 26:21-32.
4. Holick M.F. Deficiency of sunlight and vitamin D. BMJ 2008, 336:1318-1319.
5. Porojnicu A.C., Lagunova Z., Robsahm T.E., Berg J.P., Dahlback A., Moan J. Changes in risk of death from breast cancer with season and latitude: sun exposure and breast cancer survival in Norway. Breast Cancer Res Treat 2007, 102:323-328.
6. Porojnicu A., Robsahm T.E., Berg J.P., Moan J. Season of diagnosis is a predictor of cancer survival. Sun-induced vitamin D may be involved: a possible role of sun-induced Vitamin D. J Steroid Biochem Mol Biol 2007, 103:675-678.
7. Mohr S.B., Garland C.F., Gorham E.D., Grant W.B., Garland F.C. Relationship between low ultraviolet B irradiance and higher breast cancer risk in 107 countries. Breast J 2008, 14:255-260.
8. Saadi H.F., Nagelkerke N., Benedict S., Qazaq H.S., Zilahi E., Mohamadiyeh M.K., et al. Predictors and relationships of serum 25 hydroxyvitamin D concentration with bone turnover markers, bone mineral density, and vitamin D receptor genotype in Emirati women. Bone 2006, 39:1136-1143.
9. Moan J., Porojnicu A.C., Dahlback A., Setlow R.B. Addressing the health benefits and risks, involving vitamin D or skin cancer, of increased sun exposure. Proc Natl Acad Sci USA 2008, 105:668-673.
10. Holick M.F. Vitamin D deficiency. N Engl J Med 2007, 357:266-281.
11. McCullough M.L., Stevens V.L., Diver W.R., Feigelson H.S., Rodriguez C., Bostick R.M., et al. Vitamin D pathway gene polymorphisms, diet, and risk of postmenopausal breast cancer: a nested case-control study. Breast Cancer Res 2007, 9:R9.
12. Prentice A. Vitamin D deficiency: a global perspective. Nutr Rev 2008, 66:S153-S164.
13. Holick M.F. Resurrection of vitamin D deficiency and rickets. J Clin Invest 2006, 116:2062-2072.
14. Anderson P.H., Sawyer R.K., May B.K., O'Loughlin P.D., Morris H.A. 25-Hydroxyvitamin D requirement for maintaining skeletal health utilising a Sprague-Dawley rat model. J Steroid Biochem Mol Biol 2007, 103:592-595.
15. Bouillon R., Bischoff-Ferrari H., Willett W. Vitamin D and health: perspectives from mice and man. J Bone Miner Res 2008, 23:974-979.
16. Holick M.F. Vitamin D: a millenium perspective. J Cell Biochem 2003, 88:296-307.
17. Mead M.N. Benefits of sunlight: a bright spot for human health. Environ Health Perspect 2008, 116:A160-A167.
18. Holick M.F. Vitamin D and sunlight: strategies for cancer prevention and other health benefits. Clin J Am Soc Nephrol 2008, 3:1548-1554.
19. Lipkin M., Newmark H.L. Vitamin D: calcium and prevention of breast cancer: a review. J Am Coll Nutr 1999, 18:392S-397S.
20. Abbas S., Linseisen J., Slanger T., Kropp S., Mutschelknauss E.J., Flesch-Janys D., et al. Serum 25-hydroxyvitamin D and risk of post-menopausal breast cancer-results of a large case-control study. Carcinogenesis 2008, 29:93-99.
21. Giovannucci E. The epidemiology of vitamin D and cancer incidence and mortality: a review (United States). Cancer Causes Control 2005, 16:83-95.
22. Goodwin P.J., Ennis M., Pritchard K.I., Koo J., Hood N. Prognostic effects of 25-hydroxyvitamin D levels in early breast cancer. J Clin Oncol 2009, 27:3757-3763.
23. Neuhouser M.L., Sorensen B., Hollis B.W., Ambs A., Ulrich C.M., McTiernan A., et al. Vitamin D insufficiency in a multiethnic cohort of breast cancer survivors. Am J Clin Nutr 2008, 88:133-139.
24. Mundy G.R. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer 2002, 2:584-593.
25. Guise T.A., Mundy G.R. Cancer and bone. Endocr Rev 1998, 19:18-54.
26. Zheng Y., Zhou H., Fong-Yee C., Modzelewski J.R., Seibel M.J., Dunstan C.R. Bone resorption increases tumour growth in a mouse model of osteosclerotic breast cancer metastasis. Clin Exp Metastasis 2008, 25:559-567.
27. Szentirmai M., Constantinou C., Rainey J.M., Loewenstein J.E. Hypocalcemia due to avid calcium uptake by osteoblastic metastases of prostate cancer. West J Med 1995, 163:577-578.
28. Zheng Y., Zhou H., Modzelewski J.R., Kalak R., Blair J.M., Seibel M.J., et al. Accelerated bone resorption, due to dietary calcium deficiency, promotes breast cancer tumor growth in bone. Cancer Res 2007, 67:9542-9548.
29. Ooi L.L., Zhou H., Kalak R., Zheng Y., Conigrave A.D., Seibel M.J., et al. Vitamin D deficiency promotes human breast cancer growth in a murine model of bone metastasis. Cancer Res 2010, 70:1835-1844.
30. Simonet W.S., Lacey D.L., Dunstan C.R., Kelley M., Chang M.S., Luthy R., et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 1997, 89:309-319.
31. Bult P., Manders P., Straatman H.M.P.M., Tjan-Heijnen V.C.G., Beex L.V.A.M., Hendriks J., et al. In primary breast cancer the mitotic activity yields similar prognostic information as the histological grade: a study with long-term follow-up. Breast Cancer Res Treat 2009, [Epub ahead of print].
32. Ladekarl M. Choice of methodology for quantifying cancer structures in tissue sections. A comparison of 2- and 3-dimensional estimators of mitotic activity, cellularity and nuclear size in breast cancer. Anal Quant Cytol Histol 2004, 26:97-104.
33. Mehta R.R., Graves J.M., Hart G.D., Shilkaitis A., Das Gupta T.K. Growth and metastasis of human breast carcinomas with matrigel in athymic mice. Breast Cancer Res Treat 1993, 25:65-71.
34. Swami S., Krishnan A.V., Feldman D. 1alpha, 25-Dihydroxyvitamin D3 down-regulates estrogen receptor abundance and suppresses estrogen actions in MCF-7 human breast cancer cells. Clin Cancer Res 2000, 6:3371-3379.
35. Mehta R.R., Graves J.M., Hart G.D., Shilkaitis A., Das Gupta T.K. Growth and metastasis of human breast carcinomas with Matrigel in athymic mice. Breast Cancer Res Treat 1993, 25:65-71.
36. Siclari V.A., Guise T.A., Chirgwin J.M. Molecular interactions between breast cancer cells and the bone microenvironment drive skeletal metastases. Cancer Metastasis Rev 2006, 25:621-633.
37. Diamond P., Labrinidis A., Martin S.K., Farrugia A.N., Gronthos S., To L.B., et al. Targeted disruption of the CXCL12/CXCR4 axis inhibits osteolysis in a murine model of myeloma-associated bone loss. J Bone Miner Res 2009, 24:1150-1161.
38. Ikeda K. Vitamin D: osteoclastogenesis and bone resorption: from mechanistic insight to the development of new analogs. Endocr J 2007, 54:1-6.
39. Shibata T., Shira-Ishi A., Sato T., Masaki T., Masuda A., Hishiya A., et al. Vitamin D hormone inhibits osteoclastogenesis in vivo by decreasing the pool of osteoclast precursors in bone marrow. J Bone Miner Res 2002, 17:622-629.
40. Evans C.E., Ward C., Braidman I.P. Breast carcinomas synthesize factors which influence osteoblast-like cells independently of osteoclasts in vitro. J Endocrinol 1991, 128:R5-R8.
41. Yin J.J., Mohammad K.S., Kakonen S.M., Harris S., Wu-Wong J.R., Wessale J.L., et al. A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases. Proc Natl Acad Sci U S A 2003, 100:954-959.
42. Yi B., Williams P.J., Niewolna M., Wang Y., Yoneda T. Tumor-derived platelet-derived growth factor-BB plays a critical role in osteosclerotic bone metastasis in an animal model of human breast cancer. Cancer Res 2002, 62:917-923.
43. Dai J., Keller J., Zhang J., Lu Y., Yao Z., Keller E.T. Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism. Cancer Res 2005, 65:8274-8285.
44. Feeley B.T., Gamradt S.C., Hsu W.K., Liu N., Krenek L., Robbins P., et al. Influence of BMPs on the formation of osteoblastic lesions in metastatic prostate cancer. J Bone Miner Res 2005, 20:2189-2199.
45. Simonet W.S., Lacey D.L., Dunstan C.R., Kelley M., Chang M.S., Luthy R., et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 1997, 89:309-319.
46. Mastro A.M., Gay C.V., Welch D.R. The skeleton as a unique environment for breast cancer cells. Clin Exp Metastasis 2003, 20:275-284.
47. Deeb K.K., Trump D.L., Johnson C.S. Vitamin D signalling pathways in cancer: potential for anticancer therapeutics. Nat Rev Cancer 2007, 7:684-700.
48. Townsend K., Banwell C.M., Guy M., Colston K.W., Mansi J.L., Stewart P.M., et al. Autocrine metabolism of vitamin D in normal and malignant breast tissue. Clin Cancer Res 2005, 11:3579-3586.
49. Koga M., Eisman J.A., Sutherland R.L. Regulation of epidermal growth factor receptor levels by 1, 25-dihydroxyvitamin D3 in human breast cancer cells. Cancer Res 1988, 48:2734-2739.
50. McCarthy K., Laban C., Bustin S.A., Ogunkolade W., Khalaf S., Carpenter R., et al. Expression of 25-hydroxyvitamin D-1-alpha-hydroxylase, and vitamin D receptor mRNA in normal and malignant breast tissue. Anticancer Res 2009, 29:155-157.
51. Marchionatti A.M., Picotto G., Narvaez C.J., Welsh J., Tolosa de Talamoni N.G. Antiproliferative action of menadione and 1, 25(OH)2D3 on breast cancer cells. J Steroid Biochem Mol Biol 2009, 113:227-232.
52. Narvaez C.J., Welsh J. Role of mitochondria and caspases in vitamin D-mediated apoptosis of MCF-7 breast cancer cells. J Biol Chem 2001, 276:9101-9107.
53. Sergeev I.N. Calcium signaling in cancer and vitamin D. J Steroid Biochem Mol Biol 2005, 97:145-151.
54. Pirianov G., Colston K.W. Interaction of vitamin D analogs with signaling pathways leading to active cell death in breast cancer cells. Steroids 2001, 66:309-318.