메뉴 건너뛰기




Volumn 22, Issue 4, 2010, Pages 1223-1230

Higher cathepsin B levels in plasma in Alzheimer's disease compared to healthy controls

Author keywords

Alzheimer's disease; biomarkers; case control study; cathepsin B; cystatin C; epidemiology; risk factor

Indexed keywords

ALBUMIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; CATHEPSIN B; CYSTATIN C; TAU PROTEIN;

EID: 79751521177     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2010-101023     Document Type: Article
Times cited : (77)

References (28)
  • 1
    • 32044447659 scopus 로고    scopus 로고
    • An estimate of the worldwide prevalence and direct costs of dementia in 2003
    • DOI 10.1159/000090733
    • Wimo A, Jonsson L, Winblad B (2006) An estimate of the worldwide prevalence and direct costs of dementia in 2003. Dement Geriatr Cogn Disord 21, 175-181. (Pubitemid 43201328)
    • (2006) Dementia and Geriatric Cognitive Disorders , vol.21 , Issue.3 , pp. 175-181
    • Wimo, A.1    Jonsson, L.2    Winblad, B.3
  • 2
    • 0033600274 scopus 로고    scopus 로고
    • Translating cell biology into therapeutic advances in Alzheimer's disease
    • Selkoe DJ (1999) Translating cell biology into therapeutic advances in Alzheimer's disease. Nature 399, A23-31.
    • (1999) Nature , vol.399
    • Selkoe, D.J.1
  • 3
    • 0035081475 scopus 로고    scopus 로고
    • Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein
    • Selkoe DJ (2001) Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein. J Alzheimers Dis 3, 75-80.
    • (2001) J Alzheimers Dis , vol.3 , pp. 75-80
    • Selkoe, D.J.1
  • 5
    • 0025373508 scopus 로고
    • Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing
    • Sisodia SS, Koo EH, Beyreuther K, Unterbeck A, Price DL (1990) Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing. Science 248, 492-495.
    • (1990) Science , vol.248 , pp. 492-495
    • Sisodia, S.S.1    Koo, E.H.2    Beyreuther, K.3    Unterbeck, A.4    Price, D.L.5
  • 8
    • 33749017931 scopus 로고    scopus 로고
    • Cysteine cathepsins: Multifunctional enzymes in cancer
    • DOI 10.1038/nrc1949, PII NRC1949
    • Mohamed MM, Sloane BF (2006) Cysteine cathepsins: multifunctional enzymes in cancer. Nat Rev Cancer 6, 764-775. (Pubitemid 44450465)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.10 , pp. 764-775
    • Mohamed, M.M.1    Sloane, B.F.2
  • 10
    • 0025355591 scopus 로고
    • Lysosomal proteinase antigens are prominently localized within senile plaques of Alzheimer's disease: Evidence for a neuronal origin
    • DOI 10.1016/0006-8993(90)90456-L
    • Cataldo AM, Thayer CY, Bird ED, Wheelock TR, Nixon RA (1990) Lysosomal proteinase antigens are prominently localized within senile plaques of Alzheimer's disease: evidence for a neuronal origin. Brain Res 513, 181-192. (Pubitemid 20132254)
    • (1990) Brain Research , vol.513 , Issue.2 , pp. 181-192
    • Cataldo, A.M.1    Thayer, C.Y.2    Bird, E.D.3    Wheelock, T.R.4    Nixon, R.A.5
  • 12
    • 26844559355 scopus 로고    scopus 로고
    • Inhibition of cathepsin B reduces β-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: Evidence for cathepsin B as a candidate β-secretase of Alzheimer's disease
    • DOI 10.1515/BC.2005.108
    • Hook V, Toneff T, Bogyo M, Greenbaum D, Medzihradszky KF, Neveu J, Lane W, Hook G, Reisine T (2005) Inhibition of cathepsin B reduces beta-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate beta-secretase of Alzheimer's disease. Biol Chem 386, 931-940. (Pubitemid 41448149)
    • (2005) Biological Chemistry , vol.386 , Issue.9 , pp. 931-940
    • Hook, V.1    Toneff, T.2    Bogyo, M.3    Greenbaum, D.4    Medzihradszky, K.F.5    Neveu, J.6    Lane, W.7    Hook, G.8    Reisine, T.9
  • 13
    • 62449097363 scopus 로고    scopus 로고
    • Cathep-sins B and L differentially regulate amyloid precursor protein processing
    • Klein DM, Felsenstein KM, Brenneman DE (2009) Cathep-sins B and L differentially regulate amyloid precursor protein processing. J Pharmacol Exp Ther 328, 813-821.
    • (2009) J Pharmacol Exp Ther , vol.328 , pp. 813-821
    • Klein, D.M.1    Felsenstein, K.M.2    Brenneman, D.E.3
  • 14
    • 67649656100 scopus 로고    scopus 로고
    • Genetic cathepsin B deficiency reduces beta-amyloid in trans-genic mice expressing human wild-type amyloid precursor protein
    • Hook VY, Kindy M, Reinheckel T, Peters C, Hook G (2009) Genetic cathepsin B deficiency reduces beta-amyloid in trans-genic mice expressing human wild-type amyloid precursor protein. Biochem Biophys Res Commun 386, 284-288.
    • (2009) Biochem Biophys Res Commun , vol.386 , pp. 284-288
    • Hook, V.Y.1    Kindy, M.2    Reinheckel, T.3    Peters, C.4    Hook, G.5
  • 15
    • 43149100823 scopus 로고    scopus 로고
    • Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein
    • Hook VY, Kindy M, Hook G (2008) Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein. J Biol Chem 283, 7745-7753.
    • (2008) J Biol Chem , vol.283 , pp. 7745-7753
    • Hook, V.Y.1    Kindy, M.2    Hook, G.3
  • 16
    • 33748524564 scopus 로고    scopus 로고
    • Antiamyloidogenic and neuroprotective functions of cathepsin B: Implications for Alzheimer's disease
    • DOI 10.1016/j.neuron.2006.07.027, PII S0896627306005976
    • Mueller-Steiner S, Zhou Y, Arai H, Roberson ED, Sun B, Chen J, Wang X, Yu G, Esposito L, Mucke L, Gan L (2006) Antiamyloidogenic and neuroprotective functions ofcathepsin B: implications for Alzheimer's disease. Neuron 51, 703-714. (Pubitemid 44374903)
    • (2006) Neuron , vol.51 , Issue.6 , pp. 703-714
    • Mueller-Steiner, S.1    Zhou, Y.2    Arai, H.3    Roberson, E.D.4    Sun, B.5    Chen, J.6    Wang, X.7    Yu, G.8    Esposito, L.9    Mucke, L.10    Gan, L.11
  • 17
    • 53849106834 scopus 로고    scopus 로고
    • Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease
    • Sun B, Zhou Y, Halabisky B, Lo I, Cho SH, Mueller-Steiner S, Devidze N, Wang X, Grubb A, Gan L (2008) Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease. Neuron 60, 247-257.
    • (2008) Neuron , vol.60 , pp. 247-257
    • Sun, B.1    Zhou, Y.2    Halabisky, B.3    Lo, I.4    Cho, S.H.5    Mueller-Steiner, S.6    Devidze, N.7    Wang, X.8    Grubb, A.9    Gan, L.10
  • 18
    • 77951060145 scopus 로고    scopus 로고
    • Proteases and proteolysis in Alzheimer disease: A multifactorial view on the disease process
    • De Strooper B Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process. Physiol Rev 90, 465-494.
    • Physiol Rev , vol.90 , pp. 465-494
    • De Strooper, B.1
  • 21
    • 0034607960 scopus 로고    scopus 로고
    • Quantification of tau phosphorylated at threonine 181 in human cerebrospinal fluid: A sandwich ELISA with a synthetic phosphopeptide for standardization
    • DOI 10.1016/S0304-3940(00)01036-3, PII S0304394000010363
    • Vanmechelen E, Vanderstichele H, Davidsson P, Van Ker-schaver E, Van Der Perre B, Sjogren M, Andreasen N, Blennow K (2000) Quantification of tau phosphorylated at threonine 181 in human cerebrospinal fluid: a sandwich ELISA with a synthetic phosphopeptide for standardization. Neurosci Lett 285, 49-52. (Pubitemid 30224621)
    • (2000) Neuroscience Letters , vol.285 , Issue.1 , pp. 49-52
    • Vanmechelen, E.1    Vanderstichele, H.2    Davidsson, P.3    Van Kerschaver, E.4    Van Der Perre, B.5    Sjogren, M.6    Andreasen, N.7    Blennow, K.8
  • 22
    • 74149089257 scopus 로고    scopus 로고
    • Blennow K Evaluation of plasma Abeta(40) and Abeta(42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment
    • Hansson O, Zetterberg H, Vanmechelen E, Vanderstichele H, Andreasson U, Londos E, Wallin A, Minthon L, Blennow K Evaluation of plasma Abeta(40) and Abeta(42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment. Neurobiol Aging 31, 357-367.
    • Neurobiol Aging , vol.31 , pp. 357-367
    • Hansson, O.1    Zetterberg, H.2    Vanmechelen, E.3    Vanderstichele, H.4    Andreasson, U.5    Londos, E.6    Wallin, A.7    Minthon, L.8
  • 24
  • 26
    • 33645830780 scopus 로고    scopus 로고
    • Does the white matter matter in Alzheimer disease and cerebral amyloid angiopathy?
    • DOI 10.1212/01.wnl.0000196863.43951.44, PII 0000611420060110000004
    • Lee JM, Markus HS (2006) Does the white matter matter in Alzheimer disease and cerebral amyloid angiopathy? Neurology 66, 6-7. (Pubitemid 43739581)
    • (2006) Neurology , vol.66 , Issue.1 , pp. 6-7
    • Lee, J.-M.1    Markus, H.S.2
  • 28
    • 0034719070 scopus 로고    scopus 로고
    • Cystatin C and cathepsin B in CSF from patients with inflammatory neurologic diseases
    • Nagai A, Murakawa Y, Terashima M, Shimode K, Umegae N, Takeuchi H, Kobayashi S (2000) Cystatin C and cathepsin B in CSF from patients with inflammatory neurologic diseases. Neurology 55, 1828-1832. (Pubitemid 32103964)
    • (2000) Neurology , vol.55 , Issue.12 , pp. 1828-1832
    • Nagai, A.1    Murakawa, Y.2    Terashima, M.3    Shimode, K.4    Umegae, N.5    Takeuchi, H.6    Kobayashi, S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.