Peroxynitrite-induced modification of H2A histone presents epitopes which are strongly bound by human anti-DNA autoantibodies: Role of peroxynitrite-modified-H2A in SLE induction and progression

Human Immunology

Volumn 72, Issue 3, 2011, Pages 219-225

  Dixit, Kiran ^a   Khan, M Asad ^b   Sharma, Y D ^b   Moinuddin, ^a   Alam, Khursheed ^a  

^a ALIGARH MUSLIM UNIVERSITY   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Autoantibodies; H2A histone; Nitrotyrosine; Peroxynitrite; SLE

Indexed keywords

3 NITROTYROSINE; AUTOANTIGEN; CARBONYL DERIVATIVE; DNA ANTIBODY; EPITOPE; HISTONE H2A; NUCLEIC ACID; PEROXYNITRITE; TYROSINE;

ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; CYTOPLASM; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; NITRATION; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANTIBODIES, ANTINUCLEAR; AUTOANTIBODIES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; HISTONES; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; NITRO COMPOUNDS; PEROXYNITROUS ACID; TYROSINE;

EID: 79651474454     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2010.12.004     Document Type: Article

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