Immunogenicity of mitochondrial DNA modified by hydroxyl radical

Cellular Immunology

Volumn 247, Issue 1, 2007, Pages 12-17

  Alam, Khurshid ^a   Moinuddin, ^a   Jabeen, Suraya ^a  

^a ALIGARH MUSLIM UNIVERSITY   (India)

Author keywords

Antibodies; Hydroxyl radical; Immunogenicity; mtDNA; SLE

Indexed keywords

CROSS REACTING ANTIBODY; DNA ANTIBODY; HYDROGEN PEROXIDE; HYDROXYL RADICAL; MITOCHONDRIAL DNA; NUCLEASE S1; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; CROSS REACTION; DNA DETERMINATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GOAT; HUMAN; IMMUNOGENICITY; IN VITRO STUDY; LIVER; NONHUMAN; PRIORITY JOURNAL; RABBIT; SYSTEMIC LUPUS ERYTHEMATOSUS; ULTRAVIOLET IRRADIATION;

ANIMALS; ANTIBODY SPECIFICITY; ANTIGEN-ANTIBODY REACTIONS; AUTOANTIBODIES; DNA DAMAGE; DNA, MITOCHONDRIAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GOATS; HUMANS; HYDROGEN PEROXIDE; HYDROXYL RADICAL; IMMUNE SERA; IMMUNOGLOBULIN G; LUPUS ERYTHEMATOSUS, SYSTEMIC; MITOCHONDRIA, LIVER; NUCLEIC ACID CONFORMATION; NUCLEIC ACID DENATURATION; RABBITS; SPECTROPHOTOMETRY, ULTRAVIOLET; ULTRAVIOLET RAYS; VACCINATION; VACCINES, SYNTHETIC;

ANIMALIA; CAPRA HIRCUS;

EID: 34648834617     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2007.06.007     Document Type: Article

References (34)

1. Ohta S. A multifunctional organelle mitochondria is involved in cell death, proliferation and disease. Curr. Med. Chem. 10 (2003) 2485-2494
2. Stevnsner T., Thorslund T., Souza-Pinto N.C., and Bohr V.A. Mitochondrial repair of 8-oxoguanine and changes with aging. Exp. Gerontol. 37 (2002) 1189-1196
3. Shoffner J.M., and Wallace D.C. Oxidative phosphorylation diseases. Disorders of two genomes. Adv. Hum. Genet. 19 (1990) 267-330
4. Wardell T.M., Ferguson E., Chinnery P.F., Borthwick G.M., Taylor R.W., Jackson G., Craft A., Lightowlers R.N., Howell N., and Turnbull D.M. Changes in the human mitochondrial genome after treatment of malignant disease. Mutat. Res. 525 (2003) 19-27
5. Takai D., Park S.H., Takada Y., Ichinose S., Kitagawa M., and Akashi M. UV-irradiation induces oxidative damage to mitochondrial DNA primarily through hydrogen peroxide: analysis of 8-oxodGuo by HPLC. Free Radic. Res. 40 (2006) 1138-1148
6. Papa S. Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications. Biochim. Biophys. Acta 1276 (1996) 87-105
7. Kang D., and Hamasaki N. Mitochondrial oxidative stress and mitochondria. Clin. Chem. Lab. Med. 41 (2003) 1281-1288
8. Richter C. Reactive oxygen and DNA damage in mitochondria. Mutat. Res. 275 (1992) 249-255
9. Luft R. The development of mitochondrial medicine. Proc. Natl. Acad. Sci. USA 91 (1994) 8731-8738
10. Wallace D.C. Mitochondrial diseases in man and mouse. Science 283 (1999) 1482-1488
11. Mirabella M., DiGiovanni S., Silvestri G., Tonali P., and Servidei S. Apoptosis in mitochondrial encephalomyopathies with mitochondrial DNA mutations: a potential pathogenic mechanism. Brain 123 (2000) 93-104
12. Mandavilli B.S., Santos J.H., and VanHouten B. Mitochondrial DNA repair and aging. Mutat. Res. 30 (2002) 127-151
13. Kim G., Sikder H., and Singh K.K. A colony color method identifies the vulnerability of mitochondria to oxidative damage. Mutagenesis 17 (2002) 375-381
14. Pisetsky D.S., Grudier J.P., and Gilkeson G.S. A role for the immunogenic DNA in the pathogenesis of systemic lupus erythematosus. Arth. Rheum. 33 (1990) 159-164
15. Nossent J., Cikes N., Kiss E., Marchesoni A., Nassonova V., Mosca M., Olesinska M., Pokorny G., Rozman B., Schneider M., Vlachoyiannopoulos P.G., and Swaak A. Current causes of death in systemic lupus erythematosus in Europe, 2000-2004: relation to disease activity and damage accrual. Lupus 16 (2007) 309-317
16. Alam K., and Ali R. Human autoantibody binding to multiple conformations of DNA. Biochem. Int. 26 (1992) 597-605
17. Ara J., and Ali R. Reactive oxygen species modified DNA fragments of varying size are the preferred antigen for human anti-DNA autoantibodies. Immunol. Lett. 34 (1992) 195-200
18. Alam K., Islam N., Hasan R., Ali A., and Ali R. Naturally occurring SLE anti-DNA antibodies recognize unique conformation on DNA-lysine photoadduct. Microbiol. Immunol. 36 (1992) 1003-1007
19. Chatterjee B., and Rao G.R.K. A simple method for purification of mtDNA. Indian J. Biochem. Biophys. 21 (1984) 378-380
20. Alam K., Ali A., and Ali R. The effect of hydroxyl radical on the antigenicity of native DNA. FEBS Lett. 319 (1993) 66-70
21. Goding J.W. Use of staphylococcal protein-A as an immunological reagent. Immuol. Methods 20 (1976) 241-253
22. Ali R., and Alam K. Evaluation of antibodies against oxygen free radical-modified DNA by ELISA. In: Armstrong D. (Ed). Methods in molecular biology: oxidative stress biomarkers and antioxidant protocols. first ed. vol. 186 (2002), Humana Press, New Jersey 171-181
23. Waris G., and Alam K. Immunogenicity of superoxide radical modified-DNA: studies on induced antibodies and SLE anti-DNA autoantibodies. Life Sci. 75 (2004) 2633-2642
24. Pisetsky D.S. The immunologic properties of DNA. J. Immunol. 156 (1996) 421-423
25. Kreig A.M., Yi A., Matson S., Waldschmidt T.J., Bishop G.A., Teasdale R., Koretzky G.A., and Klinman D.M. CpG motifs in bacterial DNA triggers B-cell activation. Nature (London) 374 (1995) 546-549
26. Sato Y., Roman M., Tighs H., Lee D., Corr M., Nguyen M., Silverman G.J., Lotz M., Carson D.A., and Raz E. Immunostimulatory DNA sequences necessary for effective intra-dermal gene immunization. Science 273 (1996) 352-354
27. Grifantini R., Finco O., Bartolini E., Draghi M., Giudice G.D., Kochen C., Thomas A., Abrignain S., and Grandi G. Multi-plasmid DNA vaccination avoids antigenic competition and enhances immunogenicity of a poorly immunogenic plasmid. Eur. J. Immunol. 28 (1998) 1225-1232
28. Arif Z., and Ali R. Antigenicity of poly(dA-dT).poly(dA-dT) photocrosslinked with 8-methoxypsoralen. Arch. Biochem. Biophys. 329 (1996) 191-198
29. Ahmad J., Ashok B.T., and Ali R. Reactive oxygen species modified thymine and poly(dT) represent unique epitope for human anti-DNA autoantibodies. Immunol. Lett. 58 (1997) 69-74
30. Mamula M.J. Lupus autoimmunity: from peptides to particles. Immunol. Rev. 144 (1995) 301-314
31. Zack D.J., Yamamoto K., Wong A.L., Stempniak M., French C., and Weisbart R.H. DNA mimics a self-protein that may be a target for some anti-DNA autoantibodies in systemic lupus erythematosus. J. Immunol. 154 (1994) 1987-1994
32. Desai D.D., Krishnan M.P., Swindle J.T., and Marion T.N. Antigen-specific induction of antibodies against native mammalian DNA in non-autoimmune mice. J. Immunol. 151 (1993) 1614-1626
33. Richter C. Oxidative damage to mitochondrial DNA and its relationship to ageing. Int. J. Biochem. Cell. Biol. 27 (1995) 647-653
34. Richter C. Do mitochondrial DNA fragments promote cancer and ageing?. FEBS Lett. 241 (1988) 1-5