Disruption of CLOCK-BMAL1 transcriptional activity is responsible for aryl hydrocarbon receptor-mediated regulation of period1 gene

Toxicological Sciences

Volumn 115, Issue 1, 2010, Pages 98-108

  Xu, Can Xin ^a,b   Krager, Stacey L ^a   Liao, Duan Fang ^b,c   Tischkau, Shelley A ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTH CHINA   (China)

^c HUNAN UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

AhR activation; BMAL1; Circadian rhythm; Ebox; Gene regulation; Liver; Per1

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; BETA NAPTHOFLAVONE; PER1 PROTEIN; PROTEIN BMAL1; TRANSCRIPTION FACTOR CLOCK; UNCLASSIFIED DRUG; ARNTL PROTEIN, MOUSE; CIRCADIAN RHYTHM SIGNALING PROTEIN; CLOCK PROTEIN, MOUSE; MESSENGER RNA; PER1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR ARNTL;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CIRCADIAN RHYTHM; DISEASE ASSOCIATION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME REGULATION; GENE REPRESSION; HEMATOPOIETIC STEM CELL; HEPATOMA CELL; LOCOMOTION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; STEM CELL; ANIMAL; C57BL MOUSE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; LIVER CELL; LIVER CELL CARCINOMA; LIVER TUMOR; MALE; METABOLISM; PHYSIOLOGY; POLLUTANT; TUMOR CELL LINE;

MURINAE; MUS;

ANIMALS; ARNTL TRANSCRIPTION FACTORS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CLOCK PROTEINS; DOWN-REGULATION; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION REGULATION; HEPATOCYTES; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; PERIOD CIRCADIAN PROTEINS; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; TETRACHLORODIBENZODIOXIN; TRANSCRIPTION, GENETIC;

EID: 79651473045     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq022     Document Type: Article

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