메뉴 건너뛰기




Volumn 4, Issue 2, 2011, Pages 215-219

Estrogen receptor α induces down-regulation of PTEN through PI3-kinase activation in breast cancer cells

Author keywords

Estrogen receptor; Phosphatase and tensin homologue; Phosphatidylinositol 3,4,5 trisphosphate; Phosphoinositide 3 oH kinase; Protein kinase cK2 or casein kinase ii

Indexed keywords

BETA ACTIN; CASEIN KINASE II; ESTROGEN RECEPTOR ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; SERINE; THREONINE; WORTMANNIN;

EID: 79551699799     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2011.412     Document Type: Article
Times cited : (27)

References (30)
  • 1
    • 0032779376 scopus 로고    scopus 로고
    • Structural assets of a tumor suppressor
    • Tonks NK and Myers MP: Structural assets of a tumor suppressor. Science 286: 2096-2097, 1999.
    • (1999) Science , vol.286 , pp. 2096-2097
    • Tonks, N.K.1    Myers, M.P.2
  • 3
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • DOI 10.1074/jbc.273.22.13375
    • Maehama T and Dixon JE: The tumor suppressor, PTEN/MMAC1, dephosphoiylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 273: 13375-13378, 1998. (Pubitemid 28268370)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.22 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 4
    • 0033571477 scopus 로고    scopus 로고
    • PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death
    • Weng LP, Smith WM, Dahia PL, et al: PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death. Cancer Res 59: 5808-5814, 1999.
    • (1999) Cancer Res , vol.59 , pp. 5808-5814
    • Weng, L.P.1    Smith, W.M.2    Dahia, P.L.3
  • 5
    • 0035869212 scopus 로고    scopus 로고
    • 1 arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase acitvity in a breast cancer model
    • Weng LP, Brown JL and Eng C: PTEN coordinates G1 arrest by down-regulating cyclin D1 via its protein phosphatase acitivity and up-regulating p27 via its lipid phosphatase acitivity in a breast cancer model. Hum Mol Genet 10: 599-604, 2001. (Pubitemid 32229364)
    • (2001) Human Molecular Genetics , vol.10 , Issue.6 , pp. 599-604
    • Weng, L.-P.1    Brown, J.L.2    Eng, C.3
  • 8
    • 0031831731 scopus 로고    scopus 로고
    • PTEN and inherited hamartoma-cancer syndromes
    • Eng C and Peacocke M: PTEN and inherited hamartoma-cancer syndromes. Nat Genet 19: 223, 1998.
    • (1998) Nat Genet , vol.19 , pp. 223
    • Eng, C.1    Peacocke, M.2
  • 9
    • 0033579163 scopus 로고    scopus 로고
    • Mutational spectra of PTEN/MMAC1 gene: A tumor suppressor with lipid phosphatase activity
    • Ali IU, Schriml LM and Dean M: Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity. J Natl Cancer Inst 91: 1922-1932, 1999.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1922-1932
    • Ali, I.U.1    Schriml, L.M.2    Dean, M.3
  • 10
    • 0032804162 scopus 로고    scopus 로고
    • Allelic loss of the PTEN region (10q23) in breast carcinomas of poor pathophenotype
    • Garcia JM, Silva JM, Dominguez G, et al: Allelic loss of the PTEN region (10q23) in breast carcinomas of poor pathophenotype. Breast Cancer Res Treat 57: 237-243, 1999.
    • (1999) Breast Cancer Res Treat , vol.57 , pp. 237-243
    • Garcia, J.M.1    Silva, J.M.2    Dominguez, G.3
  • 12
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-AKT pathway in human cancer
    • Vivanco I and Sawyers CL: The phosphatidylinositol 3-Rinase AKT pathway in human cancer. Natl Rev Cancer 2: 489-501, 2002. (Pubitemid 37328931)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.7 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 13
    • 23844530876 scopus 로고    scopus 로고
    • Reduced expression of PTEN protein and its prognostic implications in invasive ductal carcinoma of the breast
    • DOI 10.1159/000086981
    • Tsutsui S, Inoue H, Yasuda K, Suzuki K, Higashi H, Era S and Mori M: reduced expression of PTEN protein and its prognostic implications in invasive ductal carcinoma of the breast. Oncology 68: 398-404, 2005. (Pubitemid 41160970)
    • (2005) Oncology , vol.68 , Issue.4-6 , pp. 398-404
    • Tsutsui, S.1    Inoue, H.2    Yasuda, K.3    Suzuki, K.4    Higashi, H.5    Era, S.6    Mori, M.7
  • 14
    • 0034920457 scopus 로고    scopus 로고
    • Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancer
    • DOI 10.1038/modpathol.3880371
    • Depowski PL, Rosenthal SI and Ross JS: Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancer. Mod Pathol 14: 672-676, 2001. (Pubitemid 32667211)
    • (2001) Modern Pathology , vol.14 , Issue.7 , pp. 672-676
    • Depowski, P.L.1    Rosenthal, S.I.2    Ross, J.S.3
  • 15
    • 25644447454 scopus 로고    scopus 로고
    • Up-regulation of PI3K/Akt signaling by 17beta-estradiol through activation of estrogen receptor-alpha, but not estrogen receptor-alpha, and stimulates cell growth in breast cancer cells
    • DOI 10.1016/j.bbrc.2005.08.256, PII S0006291X05019728
    • Lee YR, Park J, Yu HN, Kim JS, Youn JH and Jung SH: Up-regulation of PI3K/Akt signaling by 17beta-estradiol through activation of estrogen receptor-alpha, but not estrogen receptor-beta, and stimulates cell growth in breast cancer cells. Biochem Biophys Res Commun 336: 1221-1226, 2005. (Pubitemid 41383452)
    • (2005) Biochemical and Biophysical Research Communications , vol.336 , Issue.4 , pp. 1221-1226
    • Lee, Y.-R.1    Park, J.2    Yu, H.-N.3    Kim, J.-S.4    Hyun, J.Y.5    Jung, S.H.6
  • 17
    • 0036488531 scopus 로고    scopus 로고
    • Endocrine-responsive breast cancer and strategies for combating resistance
    • Ali S and Coombes RC: Endocrine-responsive breast cancer and strategies for combating resistance. Nat Rev Cancer 2: 101-112, 2002. (Pubitemid 37328797)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.2 , pp. 101-112
    • Ali, S.1    Coombes, R.C.2
  • 18
    • 15844388060 scopus 로고    scopus 로고
    • Estrogen receptors and their downstream targets in cancer
    • Ikeda K and Inoue S: Estrogen receptors and their downstream targets in cancer. Arch Histol Cytol 67: 435-442, 2004.
    • (2004) Arch Histol Cytol , vol.67 , pp. 435-442
    • Ikeda, K.1    Inoue, S.2
  • 19
    • 0034727094 scopus 로고    scopus 로고
    • Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
    • Simoncini T, Hafezi-Moghadam A, Brazil DP, Ley K, Chin WW and Liao JK: interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 407: 538-541, 2000.
    • (2000) Nature , vol.407 , pp. 538-541
    • Simoncini, T.1    Hafezi-Moghadam, A.2    Brazil, D.P.3    Ley, K.4    Chin, W.W.5    Liao, J.K.6
  • 20
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM: a rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 22
    • 0035847102 scopus 로고    scopus 로고
    • The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation
    • DOI 10.1074/jbc.M009134200
    • Torres J and Pulido R: The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation. J Biol Chem 276: 993-998, 2001. (Pubitemid 32096519)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.2 , pp. 993-998
    • Torres, J.1    Pulido, R.2
  • 25
    • 13244259196 scopus 로고    scopus 로고
    • Reduced PTEN expression predicts relapse in patients with breast carcinoma treated by tamoxifen
    • DOI 10.1038/modpathol.3800296
    • Shoman N, Klassen S, McFadden A, Bickis MG, Torlakovic E and Chibbar R: Reduced PTEN expression predicts relapse in patients with breast carcinoma treated by tamoxifen. Mod Pathol 18: 250-259, 2005. (Pubitemid 40188633)
    • (2005) Modern Pathology , vol.18 , Issue.2 , pp. 250-259
    • Shoman, N.1    Klassen, S.2    McFadden, A.3    Bickis, M.G.4    Torlakovic, E.5    Chibbar, R.6
  • 26
    • 0033615538 scopus 로고    scopus 로고
    • Crystal structure of the PTEN tumor suppressor: Implications for its phosphoinositide phosphatase activity and membrane association
    • DOI 10.1016/S0092-8674(00)81663-3
    • Lee Jo, Yang H, Georgescu MM, et al: Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell 99: 323-334, 1999. (Pubitemid 29519911)
    • (1999) Cell , vol.99 , Issue.3 , pp. 323-334
    • Lee, J.-O.1    Yang, H.2    Georgescu, M.-M.3    Cristofano, A.D.4    Maehama, T.5    Shi, Y.6    Dixon, J.E.7    Pandolfi, P.8    Pavletich, N.P.9
  • 27
    • 0033946740 scopus 로고    scopus 로고
    • Phosphorylation of the PTEN tail regulates protein stability and function
    • DOI 10.1128/MCB.20.14.5010-5018.2000
    • Vazquez F, Ramswamy S, Nakamura N and Sellers WR: Phosphorylation of the PTEN tail regulates protein stability and function. MoL Cell Biol 20: 5010-5018, 2000. (Pubitemid 30431555)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.14 , pp. 5010-5018
    • Vazquez, F.1    Ramaswamy, S.2    Nakamura, N.3    Sellers, W.R.4
  • 28
    • 0026177469 scopus 로고
    • Phosphorylation of transcriptional factors and cell-cycle-dependent proteins by casein kinase II
    • Meisner H and Czech MP: Phosphorylation of transcriptional factors and cell-cycle-dependent proteins by casein kinase II. Curr Opin Cell Biol 3: 474-483, 1991. (Pubitemid 121006110)
    • (1991) Current Opinion in Cell Biology , vol.3 , Issue.3 , pp. 474-483
    • Meisner, H.1    Czech, M.P.2
  • 29
    • 0028909420 scopus 로고
    • Protein kinase 4. Protein kinase CK2: An enzyme with multiple substrates and a puzzling regulation
    • Allende JE and Allende CC: Protein kinase 4. Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation FASEB J 9: 313-323, 1995.
    • (1995) FASEB J , vol.9 , pp. 313-323
    • Allende, J.E.1    Allende, C.C.2
  • 30
    • 27444445782 scopus 로고    scopus 로고
    • Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta
    • DOI 10.1074/jbc.M503045200
    • Al-Khouri AM, Ma Y, Togo SH, Williams S and Mustelin T: Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta. J Biol Chem 280: 35195-35202, 2005. (Pubitemid 41532706)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.42 , pp. 35195-35202
    • Al-Khouri, A.M.1    Ma, Y.2    Togo, S.H.3    Williams, S.4    Mustelin, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.