An agonist sensitive, quick and simple cell-based signaling assay for determination of ligands mimicking prostaglandin E2 or E1 activity through subtype EP1 receptor: Suitable for high throughput screening

BMC Complementary and Alternative Medicine

Volumn 11, Issue , 2011, Pages

  Chillar, Annirudha J ^a   Karimi, Parastoo ^a   Tang, Kathy ^b   Ruan, Ke He ^a  

^a UNIVERSITY OF HOUSTON   (United States)

^b TR Acupuncture and Herb Clinic   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND; PLANT EXTRACT; PROSTAGLANDIN E1; PROSTAGLANDIN E2; PROSTAGLANDIN RECEPTOR; CALCIUM; HERBACEOUS AGENT; PROSTAGLANDIN E RECEPTOR; RECOMBINANT PROTEIN;

ARTICLE; CALCIUM SIGNALING; CELL ASSAY; CELL STRAIN HEK293; CONTROLLED STUDY; CYTOFLUOROMETRY; EXTRACTION; FLUORESCENCE MICROSCOPY; HERB; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; PERIPHERAL VASCULAR DISEASE; PURIFICATION; CHEMISTRY; DRUG DEVELOPMENT; DRUG POTENTIATION; EVALUATION; METABOLISM; METHODOLOGY; SIGNAL TRANSDUCTION;

ALPROSTADIL; CALCIUM; DINOPROSTONE; DRUG DISCOVERY; DRUGS, CHINESE HERBAL; HEK293 CELLS; HUMANS; LIGANDS; MICROSCOPY, FLUORESCENCE; RECEPTORS, PROSTAGLANDIN E; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 79551618390     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-11-11     Document Type: Article

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