Inhibition of rat liver fibrogenesis through noradrenergic antagonism

Hepatology

Volumn 35, Issue 2, 2002, Pages 325-331

  Dubuisson, Liliane ^a   Desmoulière, Alexis ^a   Decourt, Boris ^a   Evadé, Laetitia ^a   Bedin, Christiane ^a   Boussarie, Liliane ^a   Barrier, Laurence ^b   Vidaud, Michel ^c   Rosenbaum, Jean ^a  

^a INSERM   (France)

^b POITIERS UNIVERSITY HOSPITAL   (France)

^c FACULTÉ DES SCIENCES PHARMACEUTIQUES ET BIOLOGIQUES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; CARBON TETRACHLORIDE; MESSENGER RNA; OXIDOPAMINE; PRAZOSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FIBROGENESIS; HISTOPATHOLOGY; LIVER FIBROSIS; LIVER FUNCTION TEST; MALE; NONHUMAN; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; TREATMENT OUTCOME;

EID: 0036156737     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2002.31166     Document Type: Article

References (36)

1. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
2. Proliferation and phenotypic modulation of portal fibroblasts in the early stages of cholestatic fibrosis in the rat
3. The role of the sympathetic nervous system in promoting liver cirrhosis induced by carbon tetrachloride, using the essential hypertensive animal (SHR)
4. Demonstration of noradrenaline-immunoreactive nerve fibres in the liver
5. Effects of sympathetic denervation on liver fibroblasts: Prevention by adenosine
6. Prostaglandin F2 alpha and D2 release from primary Ito cell cultures after stimulation with noradrenaline and ATP but not adenosine
7. Growth inhibitory properties of endothelin-1 in activated human hepatic stellare cells: A cyclic adenosine monophosphate-mediated pathway. Inhibition of both extracellular signal-regulated kinase and c-Jun kinase and upregulation of endothelin B receptors
8. Administration of prostaglandin E1 analog reduces rat hepatic and Ito cell collagen gene expression and collagen accumulation after bile duct ligation injury
9. The role of the autonomic nervous system in chemicallyinduced liver damage and repair-using the essential hypertensive animal model (SHR)
10. Simple and fast solvent extraction system for selective and quantitative isolation of adrenaline, noradrenaline and dopamine from plasma and urine
11. Myofibroblasts are responsible for collagen synthesis in the stroma of human hepatocellular carcinoma: An in vivo and in vitro study
12. Construction of DNA sequences complementary to rat alpha 1 and alpha 2 collagen mRNA and their use in studying the regulation of type I collagen synthesis by 1,25dihydroxyvitamin D
13. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
14. An improvement of the single-step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction
15. Quantitation of hTERT gene expression in sporadic breast tumors with a real-time reverse transcription-polymerase chain reaction assay
16. Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family
17. Sympathetic denervation impairs epidermal healing in cutaneous wounds
18. Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver
19. Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis
20. Tissue inhibitor of metalloproteinases-1 promotes liver fibrosis development in a transgenic mouse model
21. Mechanisms of carbon tetrachloride toxicity
22. The sympathetic nervous system promotes carbon tetrachloride-induced liver cirrhosis in rats by suppressing apoptosis and enhancing the growth kinetics of regenerating hepatocytes
23. Nerves and perisinusoidal cells in human liver
24. Release of osmolytes from perfused rat liver on perivascular nerve stimulation: Alpha-adrenergic control of osmolyte efflux from parenchymal and nonparenchymal liver cells
25. Induction of betaplatelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture
26. Modulation of transforming growth factor beta receptors of rat lipocytes during the hepatic wound healing response. Enhanced binding and reduced gene expression accompany cellular activation in culture and in vivo
27. The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multireceptor complex with the epidermal growth factor receptor
28. Synaptophysin: A novel marker for human and rat hepatic stellate cells
29. Human and rat hepatic stellate cells express neurotrophins and neurotrophin receptors
30. Class VI intermediate filament protein nestin is induced during activation of rat hepatic stellate cells
31. Norepinephrine-induced cholestasis in the isolated perfused rat liver is secondary to its hemodynamic effects
32. Hepatocellular hypoxia-induced vascular endothelial growth factor expression and angiogenesis in experimental biliary cirrhosis
33. Comparison of three adrenoreceptor blocking agents in patients with cirrhosis and portal hypertension
34. Hemodynamic effects of alpha-adrenergic blockade with prazosin in cirrhotic patients with portal hypertension
35. Effect of sensory denervation with capsaicin on liver fibrosis induced by common bile duct ligation in rat
36. Mast cell, myofibroblast and nerve terminal complexes in carbon tetrachloride-induced cirrhotic rat livers