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Volumn 13, Issue 1, 2011, Pages 43-52

Irradiation, cisplatin, and 5-azacytidine upregulate cytomegalovirus promoter in tumors and muscles: Implementation of non-invasive fluorescence imaging

Author keywords

Cisplatin; CMV promoter; Demethylation; Fibrosarcoma; Fluorescence imaging; In vivo; Irradiation; Mammary carcinoma; Mice

Indexed keywords

AZACITIDINE; CISPLATIN; GREEN FLUORESCENT PROTEIN; PROTEIN P21; VIRUS VECTOR;

EID: 79551594992     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-010-0300-6     Document Type: Article
Times cited : (19)

References (39)
  • 1
    • 13644267108 scopus 로고    scopus 로고
    • Transcriptional silencing is associated with extensive methylation of the CMV promoter following adenoviral gene delivery to muscle
    • 1:CAS:528:DC%2BD2cXksVSnt70%3D 10.1002/jgm.516 15079814
    • AR Brooks RN Harkins PY Wang, et al. 2004 Transcriptional silencing is associated with extensive methylation of the CMV promoter following adenoviral gene delivery to muscle J Gene Med 6 395 404 1:CAS:528:DC%2BD2cXksVSnt70%3D 10.1002/jgm.516 15079814
    • (2004) J Gene Med , vol.6 , pp. 395-404
    • Brooks, A.R.1    Harkins, R.N.2    Wang, P.Y.3
  • 2
    • 13944253562 scopus 로고    scopus 로고
    • Demethylation using the epigenetic modifier, 5-azacytidine, increases the efficiency of transient transfection of macrophages
    • 1:CAS:528:DC%2BD2MXhvFGku70%3D 10.1194/jlr.D400014-JLR200 15520456
    • G Escher A Hoang S Georges, et al. 2005 Demethylation using the epigenetic modifier, 5-azacytidine, increases the efficiency of transient transfection of macrophages J Lipid Res 46 356 365 1:CAS:528: DC%2BD2MXhvFGku70%3D 10.1194/jlr.D400014-JLR200 15520456
    • (2005) J Lipid Res , vol.46 , pp. 356-365
    • Escher, G.1    Hoang, A.2    Georges, S.3
  • 3
    • 0142154311 scopus 로고    scopus 로고
    • Inhibitors of DNA methylation and histone deacetylation activate cytomegalovirus promoter-controlled reporter gene expression in human glioblastoma cell line U87
    • 1:CAS:528:DC%2BD3sXotVCls7Y%3D 10.1093/carcin/bgg118 12869421
    • G Grassi P Maccaroni H Kaiser, et al. 2003 Inhibitors of DNA methylation and histone deacetylation activate cytomegalovirus promoter-controlled reporter gene expression in human glioblastoma cell line U87 Carcinogenesis 24 1625 1635 1:CAS:528:DC%2BD3sXotVCls7Y%3D 10.1093/carcin/bgg118 12869421
    • (2003) Carcinogenesis , vol.24 , pp. 1625-1635
    • Grassi, G.1    MacCaroni, P.2    Kaiser, H.3
  • 4
    • 0034819732 scopus 로고    scopus 로고
    • Methylation of episomal plasmids as a barrier to transient gene expression via a synthetic delivery vector
    • 1:CAS:528:DC%2BD3MXotl2gsbw%3D 10.1016/S1389-0344(01)00100-9 11576873
    • K Hong J Sherley DA Lauffenburger 2001 Methylation of episomal plasmids as a barrier to transient gene expression via a synthetic delivery vector Biomol Eng 18 185 192 1:CAS:528:DC%2BD3MXotl2gsbw%3D 10.1016/S1389-0344(01)00100-9 11576873
    • (2001) Biomol Eng , vol.18 , pp. 185-192
    • Hong, K.1    Sherley, J.2    Lauffenburger, D.A.3
  • 5
    • 0030010409 scopus 로고    scopus 로고
    • Inactivation of the very strong HCMV immediate early promoter by DNA CpG methylation in vitro
    • 1:STN:280:DyaK283ptVOjsg%3D%3D
    • S Prosch J Stein K Staak, et al. 1996 Inactivation of the very strong HCMV immediate early promoter by DNA CpG methylation in vitro Biol Chem 377 195 201 1:STN:280:DyaK283ptVOjsg%3D%3D
    • (1996) Biol Chem , vol.377 , pp. 195-201
    • Prosch, S.1    Stein, J.2    Staak, K.3
  • 6
    • 23744490985 scopus 로고    scopus 로고
    • Detection of plasmid DNA vectors following gene transfer to the murine airways
    • 1:CAS:528:DC%2BD2MXmtlCrs7w%3D 10.1038/sj.gt.3302518 15800657
    • IA Pringle S Raman WW Sharp, et al. 2005 Detection of plasmid DNA vectors following gene transfer to the murine airways Gene Ther 12 1206 1214 1:CAS:528:DC%2BD2MXmtlCrs7w%3D 10.1038/sj.gt.3302518 15800657
    • (2005) Gene Ther , vol.12 , pp. 1206-1214
    • Pringle, I.A.1    Raman, S.2    Sharp, W.W.3
  • 7
    • 2642673611 scopus 로고    scopus 로고
    • Reactivation of the previously silenced cytomegalovirus major immediate-early promoter in the mouse liver: Involvement of NF kappa B
    • 1:CAS:528:DyaK1cXhvVCguw%3D%3D 9420214
    • P Loser GS Jennings M Strauss V Sandig 1998 Reactivation of the previously silenced cytomegalovirus major immediate-early promoter in the mouse liver: involvement of NF kappa B J Virol 72 180 190 1:CAS:528: DyaK1cXhvVCguw%3D%3D 9420214
    • (1998) J Virol , vol.72 , pp. 180-190
    • Loser, P.1    Jennings, G.S.2    Strauss, M.3    Sandig, V.4
  • 8
    • 1642277986 scopus 로고    scopus 로고
    • NF-kappa B- and c-Jun-dependent regulation of human cytomegalovirus immediate-early gene enhancer/promoter in response to lipopolysaccharide and bacterial CpG-oligodeoxynucleotides in macrophage cell line RAW 264.7
    • 1:CAS:528:DC%2BD2cXislSmsrk%3D 10.1111/j.1432-1033.2004.04011.x 15009188
    • Y Lee WJ Sohn DS Kim HJ Kwon 2004 NF-kappa B- and c-Jun-dependent regulation of human cytomegalovirus immediate-early gene enhancer/promoter in response to lipopolysaccharide and bacterial CpG-oligodeoxynucleotides in macrophage cell line RAW 264.7 Eur J Biochem 271 1094 1105 1:CAS:528: DC%2BD2cXislSmsrk%3D 10.1111/j.1432-1033.2004.04011.x 15009188
    • (2004) Eur J Biochem , vol.271 , pp. 1094-1105
    • Lee, Y.1    Sohn, W.J.2    Kim, D.S.3    Kwon, H.J.4
  • 9
    • 33748358352 scopus 로고    scopus 로고
    • Analysis of signal transduction pathways in macrophages using expression vectors with CMV promoters: A cautionary tale
    • 1:CAS:528:DC%2BD28XpvFamtbk%3D 10.1007/s10753-006-9005-z 16865543
    • M Ramanathan G Hasko SJ Leibovich 2005 Analysis of signal transduction pathways in macrophages using expression vectors with CMV promoters: a cautionary tale Inflammation 29 94 102 1:CAS:528:DC%2BD28XpvFamtbk%3D 10.1007/s10753-006-9005-z 16865543
    • (2005) Inflammation , vol.29 , pp. 94-102
    • Ramanathan, M.1    Hasko, G.2    Leibovich, S.J.3
  • 10
    • 0034821325 scopus 로고    scopus 로고
    • Regulation of adenovirus-mediated elafin transgene expression by bacterial lipopolysaccharide
    • 1:CAS:528:DC%2BD3MXls1WgsLc%3D 10.1089/104303401750298553 11485631
    • AJ Simpson GA Cunningham DJ Porteous C Haslett JM Sallenave 2001 Regulation of adenovirus-mediated elafin transgene expression by bacterial lipopolysaccharide Hum Gene Ther 12 1395 1406 1:CAS:528:DC%2BD3MXls1WgsLc%3D 10.1089/104303401750298553 11485631
    • (2001) Hum Gene Ther , vol.12 , pp. 1395-1406
    • Simpson, A.J.1    Cunningham, G.A.2    Porteous, D.J.3    Haslett, C.4    Sallenave, J.M.5
  • 11
    • 0025156930 scopus 로고
    • Cell type-specific induction of the major immediate early enhancer of human cytomegalovirus by cyclic-amp
    • 1:CAS:528:DyaK3cXhtFeit7Y%3D 10.1099/0022-1317-71-1-105 2154528
    • T Stamminger H Fickenscher B Fleckenstein 1990 Cell type-specific induction of the major immediate early enhancer of human cytomegalovirus by cyclic-amp J Gen Virol 71 105 113 1:CAS:528:DyaK3cXhtFeit7Y%3D 10.1099/0022-1317-71-1-105 2154528
    • (1990) J Gen Virol , vol.71 , pp. 105-113
    • Stamminger, T.1    Fickenscher, H.2    Fleckenstein, B.3
  • 12
    • 0032518162 scopus 로고    scopus 로고
    • Activation of stress-activated MAP protein kinases up-regulates expression of transgenes driven by the cytomegalovirus immediate/early promoter
    • 1:CAS:528:DyaK1cXnvVSqsA%3D%3D 10.1093/nar/26.2.486 9421504
    • W Bruening B Giasson W Mushynski HD Durham 1998 Activation of stress-activated MAP protein kinases up-regulates expression of transgenes driven by the cytomegalovirus immediate/early promoter Nucleic Acids Res 26 486 489 1:CAS:528:DyaK1cXnvVSqsA%3D%3D 10.1093/nar/26.2.486 9421504
    • (1998) Nucleic Acids Res , vol.26 , pp. 486-489
    • Bruening, W.1    Giasson, B.2    Mushynski, W.3    Durham, H.D.4
  • 13
    • 41549114263 scopus 로고    scopus 로고
    • Radiation enhances adenoviral gene therapy in pancreatic cancer via activation of cytomegalovirus promoter and increased adenovirus uptake
    • 1:CAS:528:DC%2BD1cXjtleisrY%3D 10.1158/1078-0432.CCR-07-0933 18347189
    • T Egami K Huchida K Mizumoto, et al. 2008 Radiation enhances adenoviral gene therapy in pancreatic cancer via activation of cytomegalovirus promoter and increased adenovirus uptake Clin Cancer Res 14 1859 1867 1:CAS:528: DC%2BD1cXjtleisrY%3D 10.1158/1078-0432.CCR-07-0933 18347189
    • (2008) Clin Cancer Res , vol.14 , pp. 1859-1867
    • Egami, T.1    Huchida, K.2    Mizumoto, K.3
  • 14
    • 35948992586 scopus 로고    scopus 로고
    • Chemotherapeutic agents up-regulate the cytomegalovirus promoter: Implications for bioluminescence imaging of tumor response to therapy
    • 1:CAS:528:DC%2BD2sXht1erurrM 10.1158/0008-5472.CAN-07-1955
    • RU Svensson JM Barnes OW Rokhlin NB Cohen MD Henry 2007 Chemotherapeutic agents up-regulate the cytomegalovirus promoter: implications for bioluminescence imaging of tumor response to therapy Cance Res 67 10445 10454 1:CAS:528:DC%2BD2sXht1erurrM 10.1158/0008-5472.CAN-07-1955
    • (2007) Cance Res , vol.67 , pp. 10445-10454
    • Svensson, R.U.1    Barnes, J.M.2    Rokhlin, O.W.3    Cohen, N.B.4    Henry, M.D.5
  • 15
    • 35549009761 scopus 로고    scopus 로고
    • Non-invasive imaging in gene therapy
    • 10.1038/sj.mt.6300272
    • JK Raty T Liimatainen MU Kaikkonen, et al. 2007 Non-invasive imaging in gene therapy Mol Ther 15 2052 10.1038/sj.mt.6300272
    • (2007) Mol Ther , vol.15 , pp. 2052
    • Raty, J.K.1    Liimatainen, T.2    Kaikkonen, M.U.3
  • 16
    • 46749140321 scopus 로고    scopus 로고
    • Molecular-genetic imaging based on reporter gene expression
    • 1:CAS:528:DC%2BD1cXotFahu70%3D 10.2967/jnumed.107.045955
    • JH Kang JK Chung 2008 Molecular-genetic imaging based on reporter gene expression J Nuc Med 49 164S 179S 1:CAS:528:DC%2BD1cXotFahu70%3D 10.2967/jnumed.107.045955
    • (2008) J Nuc Med , vol.49
    • Kang, J.H.1    Chung, J.K.2
  • 17
    • 21444434097 scopus 로고    scopus 로고
    • Renal ischemia/reperfusion injury activates the enhancer domain of the human cytomegalovirus major immediate early promoter
    • 1:CAS:528:DC%2BD2MXmsV2lt70%3D 10.1111/j.1600-6143.2005.00912.x 15943618
    • SJ Kim TK Varghese Z Zhang, et al. 2005 Renal ischemia/reperfusion injury activates the enhancer domain of the human cytomegalovirus major immediate early promoter Am J Transplant 5 1606 1613 1:CAS:528:DC%2BD2MXmsV2lt70%3D 10.1111/j.1600-6143.2005.00912.x 15943618
    • (2005) Am J Transplant , vol.5 , pp. 1606-1613
    • Kim, S.J.1    Varghese, T.K.2    Zhang, Z.3
  • 18
    • 0027359827 scopus 로고
    • Waf1, a potential mediator of P53 tumor suppression
    • 1:CAS:528:DyaK2cXpslGguw%3D%3D 10.1016/0092-8674(93)90500-P
    • WS Eldeiry T Tokino VE Velculescu, et al. 1993 Waf1, a potential mediator of P53 tumor suppression Cell 75 817 825 1:CAS:528:DyaK2cXpslGguw%3D%3D 10.1016/0092-8674(93)90500-P
    • (1993) Cell , vol.75 , pp. 817-825
    • Eldeiry, W.S.1    Tokino, T.2    Velculescu, V.E.3
  • 19
    • 0033991755 scopus 로고    scopus 로고
    • An overview of the cell cycle arrest protein, p21(WAF1)
    • 1:CAS:528:DyaK1MXotVOhsbg%3D 10.1016/S1368-8375(99)00049-4 10928815
    • K Harada GR Ogden 2000 An overview of the cell cycle arrest protein, p21(WAF1) Oral Oncol 36 3 7 1:CAS:528:DyaK1MXotVOhsbg%3D 10.1016/S1368-8375(99) 00049-4 10928815
    • (2000) Oral Oncol , vol.36 , pp. 3-7
    • Harada, K.1    Ogden, G.R.2
  • 20
    • 0021077888 scopus 로고
    • Ts/A - A new metastasizing cell-line from A Balb/C spontaneous mammary adenocarcinoma
    • 1:STN:280:DyaL283nt1ymtQ%3D%3D 10.1007/BF00121199
    • P Nanni C Degiovanni PL Lollini G Nicoletti G Prodi 1983 Ts/A - a new metastasizing cell-line from A Balb/C spontaneous mammary adenocarcinoma Clin Exp Metas 1 373 380 1:STN:280:DyaL283nt1ymtQ%3D%3D 10.1007/BF00121199
    • (1983) Clin Exp Metas , vol.1 , pp. 373-380
    • Nanni, P.1    Degiovanni, C.2    Lollini, P.L.3    Nicoletti, G.4    Prodi, G.5
  • 21
    • 0015508682 scopus 로고
    • Evolution of cell-mediated antitumor immunity in mice bearing a syngeneic chemically induced tumor. Influence of tumor growth, surgical removal and treatment with irradiated cells
    • 10.1002/ijc.2910090302 4660932
    • J Belehradek G Barski M Thonier 1972 Evolution of cell-mediated antitumor immunity in mice bearing a syngeneic chemically induced tumor. Influence of tumor growth, surgical removal and treatment with irradiated cells Int J Cancer 9 461 469 10.1002/ijc.2910090302 4660932
    • (1972) Int J Cancer , vol.9 , pp. 461-469
    • Belehradek, J.1    Barski, G.2    Thonier, M.3
  • 23
    • 42349117417 scopus 로고    scopus 로고
    • Gene electrotransfer into murine skeletal muscle: A systematic analysis of parameters for long-term gene expression
    • 1:CAS:528:DC%2BD1cXlslagsrY%3D
    • G Tevz D Pavlin U Kamensek, et al. 2008 Gene electrotransfer into murine skeletal muscle: a systematic analysis of parameters for long-term gene expression Technol Cancer Res T 7 91 101 1:CAS:528:DC%2BD1cXlslagsrY%3D
    • (2008) Technol Cancer Res T , vol.7 , pp. 91-101
    • Tevz, G.1    Pavlin, D.2    Kamensek, U.3
  • 24
    • 14744278451 scopus 로고    scopus 로고
    • Combination nonviral interleukin-2 gene immunotherapy for head and neck cancer: From bench top to bedside
    • 10.1097/00005537-200503000-00002 15744147
    • BW O'Malley DQ Li SJ McQuone R Ralston 2005 Combination nonviral interleukin-2 gene immunotherapy for head and neck cancer: from bench top to bedside Laryngoscope 115 391 404 10.1097/00005537-200503000-00002 15744147
    • (2005) Laryngoscope , vol.115 , pp. 391-404
    • O'Malley, B.W.1    Li, D.Q.2    McQuone, S.J.3    Ralston, R.4
  • 25
    • 0026008881 scopus 로고
    • The variability in activity of the universally expressed human cytomegalovirus immediate early gene-1 enhancer promoter in transgenic mice
    • 1:CAS:528:DyaK38XjsFarug%3D%3D 10.1093/nar/19.22.6205 1956779
    • PA Furth L Hennighausen C Baker B Beatty R Woychick 1991 The variability in activity of the universally expressed human cytomegalovirus immediate early gene-1 enhancer promoter in transgenic mice Nucleic Acids Res 19 6205 6208 1:CAS:528:DyaK38XjsFarug%3D%3D 10.1093/nar/19.22.6205 1956779
    • (1991) Nucleic Acids Res , vol.19 , pp. 6205-6208
    • Furth, P.A.1    Hennighausen, L.2    Baker, C.3    Beatty, B.4    Woychick, R.5
  • 26
    • 9244230548 scopus 로고    scopus 로고
    • The enhancer domain of the human cytomegalovirus major immediate-early promoter determines cell type-specific expression in transgenic mice
    • 1:CAS:528:DyaK28Xit1Ogsrs%3D 8627801
    • JF Baskar PP Smith G Nilaver, et al. 1996 The enhancer domain of the human cytomegalovirus major immediate-early promoter determines cell type-specific expression in transgenic mice J Virol 70 3207 3214 1:CAS:528:DyaK28Xit1Ogsrs%3D 8627801
    • (1996) J Virol , vol.70 , pp. 3207-3214
    • Baskar, J.F.1    Smith, P.P.2    Nilaver, G.3
  • 27
    • 0034921775 scopus 로고    scopus 로고
    • High and sustained transgene expression in vivo from plasmid vectors containing a hybrid ubiquitin promoter
    • 1:CAS:528:DC%2BD38XhvFKiu7c%3D 10.1006/mthe.2001.0415 11472109
    • NS Yew M Przybylska RJ Ziegler DP Liu SH Cheng 2001 High and sustained transgene expression in vivo from plasmid vectors containing a hybrid ubiquitin promoter Mol Ther 4 75 82 1:CAS:528:DC%2BD38XhvFKiu7c%3D 10.1006/mthe.2001.0415 11472109
    • (2001) Mol Ther , vol.4 , pp. 75-82
    • Yew, N.S.1    Przybylska, M.2    Ziegler, R.J.3    Liu, D.P.4    Cheng, S.H.5
  • 28
    • 0033868530 scopus 로고    scopus 로고
    • Stimulatory and inhibitory action of cytokines on the regulation of hCMV-IE promoter activity in human endothelial cells
    • 1:CAS:528:DC%2BD3cXltlOqsLc%3D 10.1006/cyto.2000.0689 10930292
    • T Ritter C Brandt S Prosch, et al. 2000 Stimulatory and inhibitory action of cytokines on the regulation of hCMV-IE promoter activity in human endothelial cells Cytokine 12 1163 1170 1:CAS:528:DC%2BD3cXltlOqsLc%3D 10.1006/cyto.2000.0689 10930292
    • (2000) Cytokine , vol.12 , pp. 1163-1170
    • Ritter, T.1    Brandt, C.2    Prosch, S.3
  • 29
    • 47849083984 scopus 로고    scopus 로고
    • Epigenetic interplay between histone modifications and DNA methylation in gene silencing
    • 1:CAS:528:DC%2BD1cXpsVams7o%3D
    • T Vaissiere C Sawan Z Herceg 2008 Epigenetic interplay between histone modifications and DNA methylation in gene silencing Mutat Res-Rev Mutat 659 40 48 1:CAS:528:DC%2BD1cXpsVams7o%3D
    • (2008) Mutat Res-Rev Mutat , vol.659 , pp. 40-48
    • Vaissiere, T.1    Sawan, C.2    Herceg, Z.3
  • 30
    • 0001408994 scopus 로고
    • Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues
    • 1:CAS:528:DyaL2MXhvVSjtLc%3D 10.1073/pnas.82.5.1451
    • R Jaenisch A Schnieke K Harbers 1985 Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues P Natl Acad Sci USA 82 1451 1455 1:CAS:528:DyaL2MXhvVSjtLc%3D 10.1073/pnas.82.5.1451
    • (1985) P Natl Acad Sci USA , vol.82 , pp. 1451-1455
    • Jaenisch, R.1    Schnieke, A.2    Harbers, K.3
  • 31
    • 30744452286 scopus 로고    scopus 로고
    • Effects of epigenetic modulation on reporter gene expression: Implications for stem cell imaging
    • M Krishnan JM Park F Cao, et al. 2005 Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging Faseb J 19 106
    • (2005) Faseb J , vol.19 , pp. 106
    • Krishnan, M.1    Park, J.M.2    Cao, F.3
  • 32
    • 0032907381 scopus 로고    scopus 로고
    • 5-Azacytidine prevents transgene methylation in vivo
    • 10.1038/sj.gt.3300848 10476232
    • M Di Ianni A Terenzi K Perruccio, et al. 1999 5-Azacytidine prevents transgene methylation in vivo Gene Ther 6 703 707 10.1038/sj.gt.3300848 10476232
    • (1999) Gene Ther , vol.6 , pp. 703-707
    • Di Ianni, M.1    Terenzi, A.2    Perruccio, K.3
  • 33
    • 25844465921 scopus 로고    scopus 로고
    • Epigenetic therapy of cancer with 5-aza-2 '-deoxycytidine (decitabine)
    • 1:CAS:528:DC%2BD2MXhtFyhtbnE 10.1053/j.seminoncol.2005.07.008
    • RL Momparler 2005 Epigenetic therapy of cancer with 5-aza-2 '-deoxycytidine (decitabine) Sem Oncol 32 443 451 1:CAS:528:DC%2BD2MXhtFyhtbnE 10.1053/j.seminoncol.2005.07.008
    • (2005) Sem Oncol , vol.32 , pp. 443-451
    • Momparler, R.L.1
  • 34
    • 59649118655 scopus 로고    scopus 로고
    • Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2'-deoxycytidine
    • 1:CAS:528:DC%2BD1MXitVCqsbs%3D 10.1016/j.lfs.2008.12.015 19159630
    • T Deng Y Zhang 2009 Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2'-deoxycytidine Life Sci 84 311 320 1:CAS:528:DC%2BD1MXitVCqsbs%3D 10.1016/j.lfs.2008.12.015 19159630
    • (2009) Life Sci , vol.84 , pp. 311-320
    • Deng, T.1    Zhang, Y.2
  • 35
    • 0035057219 scopus 로고    scopus 로고
    • Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine
    • 1:CAS:528:DC%2BD3MXisVSqsro%3D 11259619
    • AR Karpf BE Moore TO Ririe DA Jones 2001 Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine Mol Pharmacol 59 751 757 1:CAS:528:DC%2BD3MXisVSqsro%3D 11259619
    • (2001) Mol Pharmacol , vol.59 , pp. 751-757
    • Karpf, A.R.1    Moore, B.E.2    Ririe, T.O.3    Jones, D.A.4
  • 36
    • 22844437430 scopus 로고    scopus 로고
    • Activation of p53/p21(Waf1/Cip1) pathway by 5-aza-2'-deoxycytidine inhibits cell proliferation, induces pro-apoptotic genes and mitogen-activated protein kinases in human prostate cancer cells
    • 1:CAS:528:DC%2BD2MXjtFels7Y%3D 15753979
    • SMK Pulukuri JS Rao 2005 Activation of p53/p21(Waf1/Cip1) pathway by 5-aza-2'-deoxycytidine inhibits cell proliferation, induces pro-apoptotic genes and mitogen-activated protein kinases in human prostate cancer cells Int J Oncol 26 863 871 1:CAS:528:DC%2BD2MXjtFels7Y%3D 15753979
    • (2005) Int J Oncol , vol.26 , pp. 863-871
    • Pulukuri, S.M.K.1    Rao, J.S.2
  • 37
    • 2442622595 scopus 로고    scopus 로고
    • 5-Aza-2'-deoxycytidine activates the p53/p21(Waf1/Cip1) pathway to inhibit cell proliferation
    • 1:CAS:528:DC%2BD2cXivVKgs7w%3D 10.1074/jbc.M311703200 14722112
    • WG Zhu T Hileman Y Ke, et al. 2004 5-Aza-2'-deoxycytidine activates the p53/p21(Waf1/Cip1) pathway to inhibit cell proliferation J Biol Chem 279 15161 15166 1:CAS:528:DC%2BD2cXivVKgs7w%3D 10.1074/jbc.M311703200 14722112
    • (2004) J Biol Chem , vol.279 , pp. 15161-15166
    • Zhu, W.G.1    Hileman, T.2    Ke, Y.3
  • 38
    • 13244275048 scopus 로고    scopus 로고
    • 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45-and p53-dependent mechanisms
    • 1:CAS:528:DC%2BD2MXhsVCnsLk%3D 10.1124/jpet.104.074195 15547111
    • R Schneider-Stock M ab-Assef A Rohrbeck, et al. 2005 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45-and p53-dependent mechanisms J Pharmacol Exp Ther 312 525 536 1:CAS:528:DC%2BD2MXhsVCnsLk%3D 10.1124/jpet.104.074195 15547111
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 525-536
    • Schneider-Stock, R.1    Ab-Assef, M.2    Rohrbeck, A.3
  • 39
    • 34548572068 scopus 로고    scopus 로고
    • Doxorubicin enhances the expression of transgene under control of the CMV promoter in anaplastic thyroid carcinoma cells
    • 1:CAS:528:DC%2BD2sXhtFGgsLnE 10.2967/jnumed.106.038612 17704247
    • KI Kim JH Kang JK Chung, et al. 2007 Doxorubicin enhances the expression of transgene under control of the CMV promoter in anaplastic thyroid carcinoma cells J Nucl Med 48 1553 1561 1:CAS:528:DC%2BD2sXhtFGgsLnE 10.2967/jnumed.106. 038612 17704247
    • (2007) J Nucl Med , vol.48 , pp. 1553-1561
    • Kim, K.I.1    Kang, J.H.2    Chung, J.K.3


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