Characterization and modeling of nonlinear hydrophobic interaction chromatographic systems

Journal of Chromatography A

Volumn 1218, Issue 9, 2011, Pages 1219-1226

  Nagrath, Deepak ^a   Xia, Fang ^b   Cramer, Steven M ^c  

^a Rice University   (United States)

^b AMGEN INC   (United States)

^c RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

General rate model; Hydrophobic interaction chromatography; Preferential interaction isotherm

Indexed keywords

CHROMATOGRAPHIC SYSTEMS; DISPLACEMENT CHROMATOGRAPHY; DISPLACERS; GENERAL RATE MODEL; HYDROPHOBIC INTERACTION CHROMATOGRAPHY; HYDROPHOBIC INTERACTIONS; LIMITING STEP; MODEL PROTEINS; MODELING APPROACH; NON-LINEAR; PREFERENTIAL INTERACTION; PREFERENTIAL INTERACTION ISOTHERM; PROTEIN TRANSPORT; RATE MODELS; SEPARATION SYSTEMS; SHOCK LAYER; SOLUTE PROFILES;

ADSORPTION; COMPUTER SIMULATION; DIFFUSION IN SOLIDS; HYDROPHOBICITY; ISOTHERMS; MATHEMATICAL MODELS; PROTEINS; RESINS; SURFACE DIFFUSION;

HYDROPHOBIC CHROMATOGRAPHY;

LECTIN; LYSOZYME; PROTEIN;

ACCURACY; ADSORPTION; ARTICLE; DIFFUSION; HYDROPHOBIC INTERACTION CHROMATOGRAPHY; ISOTHERM; MATHEMATICAL ANALYSIS; POROSITY; PREDICTION; PRIORITY JOURNAL; PROCESS MODEL; PROTEIN TRANSPORT; SEPARATION TECHNIQUE; SOLUTE;

ALGORITHMS; CHROMATOGRAPHY, LIQUID; DIFFUSION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, CHEMICAL; MURAMIDASE; POROSITY;

EID: 79551583769     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2010.12.111     Document Type: Article

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