A Hybrid Model Framework for the Optimization of Preparative Chromatographic Processes

Biotechnology Progress

Volumn 20, Issue 1, 2004, Pages 162-178

  Nagrath, Deepak ^a   Messac, Achille ^a,b   Bequette, B Wayne ^a   Cramer, S M ^a  

^a Rensselaer Polytechnic Institute   (United States)

^b RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID MODELS; PRODUCTION RATES;

ALGORITHMS; CHROMATOGRAPHIC ANALYSIS; COMPUTATIONAL METHODS; COMPUTER SIMULATION; MATHEMATICAL MODELS; OPTIMIZATION; QUADRATIC PROGRAMMING; REACTION KINETICS;

BIOTECHNOLOGY;

CHYMOTRYPSINOGEN; PANCREATIC RIBONUCLEASE;

ALGORITHM; ARTICLE; ARTIFICIAL NEURAL NETWORK; CHEMICAL MODEL; CHEMISTRY; CHROMATOGRAPHY; COMPARATIVE STUDY; COMPUTER SIMULATION; EVALUATION; METHODOLOGY;

ALGORITHMS; CHROMATOGRAPHY; CHYMOTRYPSINOGEN; COMPUTER SIMULATION; MODELS, CHEMICAL; NEURAL NETWORKS (COMPUTER); RIBONUCLEASE, PANCREATIC;

EID: 1142305974     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp034026g     Document Type: Article

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