Phorbol ester potentiates the growth inhibitory effects of troglitazone via up-regulation of PPARγ in A549 cells

Biochemical and Biophysical Research Communications

Volumn 349, Issue 2, 2006, Pages 660-667

  Kim, Hyo Jung ^a   Woo, Im Sun ^a   Kang, Eun Sil ^a   Eun, So Young ^a   Kim, Gil Hyeong ^a   Ham, Sun Ah ^a   Kim, Hye Jung ^a   Lee, Jae Heun ^a   Chang, Ki Churl ^a   Kim, Jin Hoi ^b   Lee, Hoon Taek ^c   Seo, Han Geuk ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

^b Gyeongsang National University   (South Korea)

^c Konkuk University   (South Korea)

Author keywords

ERK; G0 G1 arrest; PKC; PPAR ; Reactive oxygen species; TPA

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 CHLORO 5 NITROBENZANILIDE; ACETYLCYSTEINE; BISINDOLYLMALEIMIDE; BISINDOLYLMALEIMIDE I; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; TROGLITAZONE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; CULTIVATED LAND; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHROMANS; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DRUG SYNERGISM; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PHORBOL ESTERS; PPAR GAMMA; REACTIVE OXYGEN SPECIES; THIAZOLIDINEDIONES; UP-REGULATION;

EID: 33748417111     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.08.085     Document Type: Article

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