Functionalization of electrospun poly(ε-caprolactone) fibers with the extracellular matrix-derived peptide grgds improves guidance of schwann cell migration and axonal growth

Tissue Engineering - Part A

Volumn 17, Issue 3-4, 2011, Pages 475-486

  Bockelmann, Julia ^a,b   Klinkhammer, Kristina ^a   Von Holst, Alexander ^c   Seiler, Nadine ^a   Faissner, Andreas ^c   Brook, Gary A ^d   Klee, Doris ^a   Mey, Jörg ^a,b  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b EURON Graduate School of Neuroscience   (Netherlands)

^c RUHR UNIVERSITY BOCHUM   (Germany)

^d UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADSORPTION; BIOASSAY; CHEMICAL MODIFICATION; CYTOLOGY; ELECTROSPINNING; ENZYME ACTIVITY; ENZYMES; ETHYLENE; ETHYLENE GLYCOL; NEURONS; PEPTIDES; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; PROPYLENE; SUGARS;

3-KINASE PATHWAYS; ARTIFICIAL IMPLANTS; AXONAL GROWTH; AXONAL REGENERATION; BEST AVAILABLE TREATMENTS; BIOLOGICAL EFFECTS; BIOLOGICAL FUNCTIONS; BIOLOGICALLY ACTIVE PEPTIDES; CAPROLACTONE; CELL MIGRATION; DORSAL ROOT GANGLIA; ELECTROSPUN FIBERS; ELECTROSPUNS; EXTRACELLULAR MATRICES; EXTRACELLULAR MATRIX PROTEIN; FUNCTIONALIZATIONS; FUNCTIONALIZED; INTRACELLULAR SIGNALING; LOW LEVEL; MICROFIBERS; NERVE REPAIR; NON-SPECIFIC PROTEIN ADSORPTION; PERIPHERAL NERVES; POLY(PROPYLENE GLYCOL); SCHWANN CELLS; TIME-LAPSE VIDEO MICROSCOPY;

FIBERS;

BIOMATERIAL; GLYCYL ARGINYL GLYCYL ASPARTYL SERINE; GLYCYL-ARGINYL-GLYCYL-ASPARTYL-SERINE; OLIGOPEPTIDE; POLYCAPROLACTONE; POLYESTER;

ANIMAL; ARTICLE; CELL CULTURE; CHEMISTRY; CHICK EMBRYO; CYTOLOGY; ELECTROCHEMISTRY; INSTRUMENTATION; METHODOLOGY; NERVE FIBER; NERVE REGENERATION; PHYSIOLOGY; PROSTHESIS; ROTATION; SCHWANN CELL; SPINAL GANGLION; SYNTHESIS; TISSUE REGENERATION; ULTRASTRUCTURE;

ANIMALS; AXONS; BIOCOMPATIBLE MATERIALS; CELLS, CULTURED; CHICK EMBRYO; ELECTROCHEMISTRY; GANGLIA, SPINAL; GUIDED TISSUE REGENERATION; NERVE REGENERATION; OLIGOPEPTIDES; POLYESTERS; PROSTHESIS DESIGN; ROTATION; SCHWANN CELLS;

EID: 79551547733     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2010.0369     Document Type: Article

References (47)

1. Ichihara, S., Inada, Y., and Nakamura, T. Artificial nerve tubes and their application for repair of peripheral nerve injury: an update of current concepts. Injury 39 Suppl 4, 29, 2008.
2. Inada, Y., Hosoi, H., Yamashita, A., Morimoto, S., Tatsumi, H., Notazawa, S., Kanemaru, S., and Nakamura, T. Regeneration of peripheral motor nerve gaps with a poly-glycolic acid-collagen tube: technical case report. Neurosurgery 61, E1105, 2007.
3. Schlosshauer, B., Dreesmann, L., Schaller, H.E., and Sinis, N. Synthetic nerve guide implants in humans: a comprehensive survey. Neurosurgery 59, 740, 2006.
4. Kim, Y.T., Haftel, V.K., Kumar, S., and Bellamkonda, R.V. The role of aligned polymer fiber-based constructs in the bridging of long peripheral nerve gaps. Biomaterials 29, 3117, 2008.
5. Chew, S.Y., Mi, R., Hoke, A., and Leong, K.W. Aligned protein-polymer composite fibers enhance nerve regeneration: a potential tissue-engineering platform. Adv Funct Mat 17, 1288, 2007.
6. Ramakrishna, S., Fujihara, K., Teo, W.-E., Lim, T.-C., and Ma, Z. An Introduction to Electrospinning and Nanofibers. Singapore, World Scientific Publishing, 2005.
7. Schnell, E., Klinkhammer, K., Balzer, S., Brook, G.A., Klee, D., Dalton, P.D., and Mey, J. Guidance of glial cell migration and axonal growth on electrospun nanofibers of poly-e-caprolactone and a collagen/poly-e-caprolactone blend. Biomaterials 28, 3012, 2007.
8. Sill, T.J., and von Recum, H.A. Electrospinning: applications in drug delivery and tissue engineering. Biomaterials 29, 1989, 2008.
9. Shen, M., Garcia, I., Maier, R.V., and Horbett, T.A. Effects of adsorbed proteins and surface chemistry on foreign body giant cell formation, tumor necrosis factor alpha release and procoagulant activity of monocytes. J Biomed Mater Res A 70, 533, 2004.
10. Koh, H.S., Yong, T., Chan, C.K., and Ramakrishna, S. Enhancement of neurite outgrowth using nano-structured scaffolds coupled with laminin. Biomaterials 29, 3574, 2008.
11. Yang, F., Murugan, R., Wang, S., and Ramakrishna, S. Electrospinning of nano/micro scale poly(L-lactic acid) aligned fibers and their potential in neural tissue engineering. Biomaterials 26, 2603, 2005.
12. Lee, J.Y., Bashur, C.A., Goldstein, A.S., and Schmidt, C.E. Polypyrrole-coated electrospun PLGA nanofibers for neural tissue applications. Biomaterials 30, 4325, 2009.
13. Grafahrend, D., Lleixa, C.J., Salber, J., Dalton, P.D., Moeller, M., and Klee, D. Biofunctionalized poly(ethylene glycol)-block-poly(epsilon- caprolactone) nanofibers for tissue engineering. J Mater Sci Mater Med 19, 1479, 2008.
14. Pierschbacher, M.D., and Ruoslahti, E. Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule. Nature 309, 30, 1984.
15. Ruoslahti, E. RGD and other recognition sequences for in-tegrins. Annu Rev Cell Dev Biol 12, 697, 1996.
16. Woerly, S., Laroche, G., Marchand, R., Pato, J., Subr, V., and Ulbrich, K. Intracerebral implantation of hydrogel-coupled adhesion peptides: tissue reaction. J Neural Transplant Plast 5, 245, 1995.
17. Hersel, U., Dahmen, C., and Kessler, H. RGD modified polymers: biomaterials for stimulated cell adhesion and beyond. Biomaterials 24, 4385, 2003.
18. Liu, W.Q., Martínez, J.A., Durand, J., Wildering, W., and Zochodne, D.W. RGD-mediated adhesive interactions are important for peripheral axon outgrowth in vivo. Neurobiol Dis 34, 11, 2009.
19. Grafahrend, D., Calvet, J.L., Klinkhammer, K., Salber, J., Dalton, P.D., Mö ller, M., and Klee, D. Control of protein adsorption on functionalized electrospun fibers. Biotechnol Bioeng 101, 609, 2008.
20. Corey, J.M., Lin, D.Y., Mycek, K.B., Chen, Q., Samuel, S., Feldman, E.L., and Martin, D.C. Aligned electrospun nano-fibers specify the direction of root ganglia neurite growth. J Biomed Mater Res A 83, 636, 2007.
21. Klinkhammer, K., Seiler, N., Grafahrend, D., Mey, J., Brook, G.A., Möller, M., Dalton, P.D., and Klee, D. Deposition of electrospun fibers on reactive substrates for in vitro investigation. Tissue Eng 15, 77, 2009.
22. Goetz, H., Beginn, U., Bartelink, C.F., and Gruenbauer, H.J.M. Preparation of isophorone diisocyanate terminated star polyethers. Macromol Mater Eng 287, 223, 2002.
23. Klinkhammer, K., Bockelmann, J., Simitzis, C., Brook, G.A., Grafahrend, D., Groll, J., Möller, M., Mey, J., and Klee, D. Functionalization of electrospun fibers of poly(epsilon-caprolactone) with star shaped NCO-poly(ethylene glycol)-stat-poly(propylene glycol) for neuronal cell guidance. J Mater Sci Mater Med 21, 2637, 2010.
24. Alessi, D.R., Cuenda, A., Cohen, P., Dudley, D.T., and Saltiel, A.R. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 270, 27489, 1995.
25. Nielsen, M., Kaltoft, K., Nordahl, M., Ropke, C., Geisler, C., Mustelin, T., Dobson, P., Svejgaard, A., and Odum, N. Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines. Proc Natl Acad Sci USA 94, 6764, 1997.
26. Vlahos, C.J., Matter, W.F., Hui, K.Y., and Brown, R.F. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1- benzopyran-4-one (LY294002). J Biol Chem 269, 5241, 1994.
27. Orlova, I., Silver, L., and Gallo, G. Regulation of actomyosin contractility by PI3K in sensory axons. Dev Neurobiol 67, 1843, 2007.
28. Sango, K., Yanagisawa, H., Komuta, Y., Si, Y., and Kawano, H. Neuroprotective properties of ciliary neurotrophic factor for cultured adult rat dorsal root ganglion neurons. His-tochem Cell Biol 130, 669, 2008.
29. Patel, S., Kurpinski, K., Quigley, R., Gao, H., Hsiao, B.S., Poo, M.M., and Li, S. Bioactive nanofibers: synergistic effects of nanotopography and chemical signaling on cell guidance. Nano Lett 7, 2122, 2007.
30. Dalton, P.D., Klinkhammer, K., Salber, J., Klee, D., and Möller, M. Direct in vitro electrospinning with polymer melts. Biomacromolecules 7, 686, 2006.
31. Ghasemi-Mobarakeh, L., Prabhakaran, M.P., Morshed, M., Nasr-Esfahani, M.H., and Ramakrishna, S. Electrospun poly(epsilon-caprolactone)/gelatin nanofibrous scaffolds for nerve tissue engineering. Biomaterials 29, 4532, 2008.
32. Woerly, S., Pinet, E., de Robertis, L., Van Diep, D., and Bous-mina, M. Spinal cord repair with PHPMA hydrogel containing RGD peptides (NeuroGel). Biomaterials 22, 1095, 2001.
33. Zhang, Z., Yoo, R., Wells, M., Beebe, T.P., Jr., Biran, R., and Tresco, P. Neurite outgrowth on well-characterized surfaces: preparation and characterization of chemically and spatially controlled fibronectin and RGD substrates with good bio-activity. Biomaterials 26, 47, 2005.
34. Prabhakaran, M.P., Venugopal, J.R., Chyan, T.T., Hai, L.B., Chan, C.K., Lim, A.Y., and Ramakrishna, S. Electrospun biocomposite nanofibrous scaffolds for neural tissue engineering. Tissue Eng Part A 14, 1787, 2008.
35. Ahmed, I., Liu, H.Y., Mamiya, P.C., Ponery, A.S., Babu, A.N., Weik, T., Schindler, M., and Meiners, S. Three-dimensional nanofibrillar surfaces covalently modified with tenascin-C-derived peptides enhance neuronal growth in vitro. J Biomed Mater Res A 76, 851, 2006.
36. Dalton, P.D., and Mey, J. Neural interactions with materials. Front Biosci 14, 769, 2009.
37. Kim, B.S., Yoo, J.J., and Atala, A. Peripheral nerve regeneration using acellular nerve grafts. J Biomed Mater Res A 68, 201, 2004.
38. Moore, K., MacSween, M., and Shoichet, M. Immobilized concentration gradients of neurotrophic factors guide neur-ite outgrowth of primary neurons in macroporous scaffolds. Tissue Eng 12, 267, 2006.
39. Yu, T.T., and Shoichet, M.S. Guided cell adhesion and outgrowth in peptide-modified channels for neural tissue engineering. Biomaterials 26, 1507, 2005.
40. Luo, Y., and Shoichet, M.S. A photolabile hydrogel for guided three-dimensional cell growth and migration. Nat Mater 4, 249, 2004.
41. Tong, Y.W., and Shoichet, M.S. Enhancing the neuronal interaction on fluoropolymer surfaces with mixed peptides or spacer group linkers. Biomaterials 22, 1029, 2001.
42. Mitra, S.K., Hanson, D.A., and Schlaepfer, D.D. Focal adhesion kinase: in command and control of cell motility. Nat Rev Mol Cell Biol 6, 56, 2005.
43. Chew, S.Y., Mi, R., Hoke, A., and Leong, K.W. The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation. Biomaterials 29, 653, 2008.
44. Mosahebi, A., Simon, M., Wiberg, M., and Terenghi, G. A novel use of alginate hydrogel as Schwann cell matrix. Tissue Eng 7, 525, 2001.
45. Sperry, R.W. Chemoaffinity in the orderly growth of nerve fiber patterns and connections. Proc Natl Acad Sci USA 50, 703, 1963.
46. Mohanna, P.N., Young, R.C., Wiberg, M., and Terenghi, G. A composite poly-hydroxybutyrate-glial growth factor conduit for long nerve gap repairs. J Anat 203, 553, 2003.
47. Dodla, M.C., and Bellamkonda, R.V. Differences between the effect of anisotropic and isotropic laminin and nerve growth factor presenting scaffolds on nerve regeneration across long peripheral nerve gaps. Biomaterials 29, 33, 2008.