Site-specific integration and expression of an anti-malarial gene in transgenic Anopheles gambiae significantly reduces Plasmodium infections

PLoS ONE

Volumn 6, Issue 1, 2011, Pages

  Meredith, Janet M ^a   Basu, Sanjay ^a,b   Nimmo, Derric D ^a,c   Larget Thiery, Isabelle ^d   Warr, Emma L ^a   Underhill, Ann ^a   McArthur, Clare C ^a   Carter, Victoria ^a   Hurd, Hilary ^a   Bourgouin, Catherine ^d   Eggleston, Paul ^a  

^a KEELE UNIVERSITY   (United Kingdom)

^b VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^c OXITEC LIMITED   (United Kingdom)

^d INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN VIDA3; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG; ANTIMALARIAL AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANOPHELES GAMBIAE; ARTICLE; CONTROLLED STUDY; DNA MODIFICATION; FEMALE; GENE EXPRESSION; GENE TARGETING; GENETIC ENGINEERING; MIDGUT; MOUSE; NONHUMAN; PARASITE VECTOR; PARASITE VIRULENCE; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII; PLASMODIUM YOELII INFECTION; PROMOTER REGION; TISSUE SPECIFICITY; ANIMAL; DISEASE CARRIER; DRUG EFFECT; GENETICS; HUMAN; MALARIA; METHODOLOGY; TRANSGENE; TRANSGENIC ANIMAL;

ANOPHELES GAMBIAE; HEXAPODA; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII NIGERIENSIS; STREPTOMYCES;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANOPHELES GAMBIAE; ANTIMALARIALS; FEMALE; GENE TARGETING; HUMANS; INSECT VECTORS; MALARIA; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII; TRANSGENES;

EID: 79551536218     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014587     Document Type: Article

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