Hemolytic C-type lectin CEL-III from sea cucumber expressed in transgenic mosquitoes impairs malaria parasite development

PLoS Pathogens

Volumn 3, Issue 12, 2007, Pages 1962-1970

  Yoshida, Shigeto ^a   Shimada, Yohei ^a   Kondoh, Daisuke ^a   Kouzuma, Yoshiaki ^b   Ghosh, Anil K ^c   Jacobs Lorena, Marcelo ^c   Sinden, Robert E ^d  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b IBARAKI UNIVERSITY   (Japan)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LECTIN; PROTEIN CEL 3; UNCLASSIFIED DRUG; CEL III LECTIN, CUCUMARIA ECHINATA; CEL-III LECTIN, CUCUMARIA ECHINATA; HEMOLYTIC AGENT;

ANIMAL CELL; ANOPHELES STEPHENSI; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ERYTHROCYTE; FEMALE; HEMAGGLUTINATION TEST; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MALARIA; MIDGUT; MOUSE; NONHUMAN; OOCYTE DEVELOPMENT; PARASITE DEVELOPMENT; PARASITE TRANSMISSION; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; SEA CUCUMBER; TRANSGENIC ORGANISM; ANIMAL; ANOPHELES; BAGG ALBINO MOUSE; BROWN NORWAY RAT; CHEMISTRY; CUCUMARIA; DIGESTIVE SYSTEM; DISEASE CARRIER; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION; GENETICS; HEMOLYSIS; MALE; METABOLISM; MOLECULAR CLONING; PARASITOLOGY; PATHOGENICITY;

ANOPHELES STEPHENSI; CUCUMARIA ECHINATA; HOLOTHUROIDEA; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; RATTUS;

ANIMALS; ANOPHELES; CLONING, MOLECULAR; CUCUMARIA; DIGESTIVE SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; FEMALE; GENE EXPRESSION; HEMOLYSIS; HEMOLYTIC AGENTS; HOST-PARASITE INTERACTIONS; HUMANS; INSECT VECTORS; LECTINS; MALARIA; MALE; MICE; MICE, INBRED BALB C; ORGANISMS, GENETICALLY MODIFIED; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; RATS; RATS, INBRED BN;

EID: 37849042885     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.0030192     Document Type: Article

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