Cell surface heparan sulfates mediate internalization of the PWWP/HATH domain of HDGF via macropinocytosis to fine-tune cell signalling processes involved in fibroblast cell migration

Biochemical Journal

Volumn 433, Issue 1, 2011, Pages 127-138

  Wang, Chia Hui ^a   Davamani, Fabian ^a   Sue, Shih Che ^a,b   Lee, Shao Chen ^c   Wu, Po Long ^d   Tang, Fan Mei ^b   Shih, Chiaho ^b   Huang, Tai Huang ^b,d   Wu, Wen Guey ^a,e  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^c FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN NORMAL UNIVERSITY   (Taiwan)

^e NATIONAL SYNCHROTRON RADIATION RESEARCH CENTER   (Taiwan)

Author keywords

Cell migration; HATH domain; Heparan sulfate binding; Hepatoma derived growth factor (HDGF); Macropinocytosis; Proliferation

Indexed keywords

AMINO ACID; CELL PROTEIN; GELATINASE A; GELATINASE B; HEPARAN SULFATE; HEPATOMA DERIVED GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN HATH; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN 3T3; CELL SURFACE; CHO CELL; CONTROLLED STUDY; FIBROBLAST; INTERNALIZATION; INTRACELLULAR SIGNALING; NONHUMAN; PINOCYTOSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RECEPTOR BINDING;

3T3 CELLS; ANIMALS; CELL MEMBRANE; CELL MOVEMENT; CELL PROLIFERATION; FIBROBLASTS; HEPARITIN SULFATE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MATRIX METALLOPROTEINASES; MICE; PINOCYTOSIS; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION;

EID: 79551494867     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20100589     Document Type: Article

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