Effect of particle size of drug on conversion of crystals to an amorphous state in a solid dispersion with crospovidone

Chemical and Pharmaceutical Bulletin

Volumn 59, Issue 2, 2011, Pages 235-238

  Sugamura, Yuka ^a   Fujii, Makiko ^a   Nakanishi, Sayaka ^a   Suzuki, Ayako ^a   Shibata, Yusuke ^a,b   Koizumi, Naoya ^a   Watanabe, Yoshiteru ^a  

^a SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

^b Pharmaceutical Research Laboratories   (Japan)

Author keywords

Amorphous; Crospovidone; Particle size; Solid dispersion; Solid solid interaction

Indexed keywords

CROSPOVIDONE; INDOMETACIN; NIFEDIPINE;

AMORPHIZATION; ARTICLE; CHEMICAL INTERACTION; CHEMICAL MODIFICATION; CRYSTAL; DISPERSION; MELTING POINT; PARTICLE SIZE; PHASE TRANSITION; SOLID; THERMAL ANALYSIS; X RAY POWDER DIFFRACTION;

CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DOSAGE FORMS; PARTICLE SIZE; POVIDONE; X-RAY DIFFRACTION;

EID: 79551492832     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.59.235     Document Type: Article

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