The positive response of Ty1 retrotransposition test to carcinogens is due to increased levels of reactive oxygen species generated by the genotoxins

Archives of Toxicology

Volumn 85, Issue 1, 2011, Pages 67-74

  Dimitrov, Martin ^a   Venkov, Pencho ^b   Pesheva, Margarita ^a  

^a UNIVERSITY OF SOFIA   (Bulgaria)

^b Agricultural Academy   (Bulgaria)

Author keywords

Carcinogens; Reactive oxygen species; Ty1 retrotransposition

Indexed keywords

ACETYLCYSTEINE; ANTHRACENE; ARSENIC; BENZ[A]ANTHRACENE; BENZO[A]PYRENE; BILE ACID; BILE ACID CONJUGATE; CARCINOGEN; CHENODEOXYCHOLIC ACID; CHROMIUM; FORMAMIDE; GENOTOXIN; GLYCODEOXYCHOLIC ACID; HYDROGEN PEROXIDE; LEAD; LITHOCHOLIC ACID; MESYLIC ACID ETHYL ESTER; METAL; OXYGEN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TAURODEOXYCHOLIC ACID; TOXIN; TRANSCRIPTION FACTOR YAP1; UNCLASSIFIED DRUG; ZINC;

ARTICLE; BIOACCUMULATION; CARCINOGEN TESTING; CARCINOGENESIS; CELL LEVEL; FUNGAL CELL; FUNGAL STRAIN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RETROPOSON; SACCHAROMYCES CEREVISIAE; SURVIVAL; TY1 RETROTRANSPOSITION TEST;

ACETYLCYSTEINE; CARCINOGENS; MUTAGENICITY TESTS; MUTAGENS; REACTIVE OXYGEN SPECIES; RETROELEMENTS; SACCHAROMYCES CEREVISIAE; SUPEROXIDES;

EID: 79251595408     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-010-0542-8     Document Type: Article

References (51)

1. H Bernstein C Bernstein CM Payne K Dvorekova H Garewall 2005 Bile acids as carcinogens in human gastrointestinal cancers Mutat Res 589 47 65 1:CAS:528:DC%2BD2MXis1Wluw%3D%3D 10.1016/j.mrrev.2004.08.001 15652226
2. JS Bertram 2001 The molecular genetics of carcinogenesis Mol Aspect Med 21 167 223 10.1016/S0098-2997(00)00007-8
3. VA Bohr 2002 Repair of oxidative DNA damage in nuclear and mitochondrial DNA and some changes with aging in mammalian cells Free Radic Biol Med 32 804 812 1:CAS:528:DC%2BD38XjtVeju70%3D 10.1016/S0891-5849(02)00787-6 11978482
4. JM Curcio DG Garfinkel 1991 Single step selection for Ty1 element retrotransposition Proc Natl Acad Sci USA 88 936 940 1:CAS:528: DyaK3MXhtFGqsr8%3D 10.1073/pnas.88.3.936 1846969
5. CT Dillon PA Lay AM Bonin M Cholewa GJF Legge 2000 Permeability, cytotoxicity and genotoxicity and some Cr(VI) analogues in V79 Chinese Hamster Lung cells Chem Res Toxicol 13 742 748 1:CAS:528:DC%2BD3cXltVOisbs%3D 10.1021/tx0000116 10956062
6. Donkin SG, Ohlson DL, Teaf CM (2000) Properties and effects of metals. In: Williams PL, James RC, Roberts SM (eds) Principles of toxicology: environmental and industrial applications, 2nd edn. John Wiley, London, pp 325-345
7. Drake JW (1970) The molecular basis of mutation. Holden Day, Oakland
8. DA Eastmond JT Macgregor RS Slesinski 2008 Trivalent chromium: assessing the genotoxic risk of an essential trace element and widely used human and animal nutritional supplement Crit Rev Toxicol 38 173 190 1:CAS:528: DC%2BD1cXivVOgsb4%3D 10.1080/10408440701845401 18324515
9. J Fu X Liang Y Chen L Tang Q Zhang Q Dong 2008 Oxidative stress as a component of chromium-induced cytotoxicity in rat calvarial osteoblasts Cell Biol Toxicol 24 201 212 1:CAS:528:DC%2BD1cXkvFams78%3D 10.1007/s10565-007-9029-7 18027092
10. Garfinkel D (1992) Retroelements in microorganisms. In: Levy JA (ed) Retroviritidae. Plenum Press, New York, pp 107-136
11. M Gitan M Shababi M Kramer DJ Eide 2003 A cytosolic domain of the yeast Ztr1 zinc transporter is required for its post translational inactivation in response to zinc and cadmium J Biol Chem 278 39558 39564 1:CAS:528: DC%2BD3sXnvFantLg%3D 10.1074/jbc.M302760200 12893829
12. E Herrero J Ros G Belli E Cabiscol 2008 Redox control and oxidative stress in yeast cells Biochim Biophys Acta 1780 1217 1235 1:CAS:528: DC%2BD1cXhtVarsbfN 18178164
13. P Hsu M Liu C Hsu L Chen Y Leon Guo 1997 Lead exposure causes generation of reactive oxygen species and functional impairment in rat sperm Toxicology 122 133 143 1:CAS:528:DyaK2sXltl2rtLs%3D 10.1016/S0300-483X(97)00090-5 9274809
14. P Hsu M Liu C Hsu L Chen Y Leon Guo 1998 Effect of vitamin E and/or C on reactive oxygen species-related lead toxicity in the rat sperm Toxicology 128 169 179 1:CAS:528:DyaK1cXltFajs74%3D 10.1016/S0300-483X(98)00068-7 9750040
15. Hu H (2002) Human health and heavy metal exposure. In: McCally M (ed) Life support: the environment and human health. Chap. 4. MIT press, Cambridge
16. DJ Jamieson 1992 Saccharomyces cerevisiae has distinct adaptive responses to both hydrogen peroxide and menadione J Bacteriol 174 6678 6681 1:CAS:528:DyaK38XmsVynurs%3D 1400218
17. W Jianglong M Zeyu Z Xuan 2003 Response of Saccharomyces cerevisiae to chromium stress Proc Biochem 39 1231 1235 10.1016/S0032-9592(03)00255-3
18. WW Jung EM Kim EH Lee HJ Yun HR Ju MJ Jeong KW Hwang D Sul HS Kang 2007 Formaldehyde exposure induces airway inflammations by increasing eosinophil infiltrations through the regulation of reactive oxygen species production Envir Tox Pharm 24 174 182 1:CAS:528:DC%2BD2sXot1yjsbY%3D 10.1016/j.etap.2007.05.001
19. JM Kim S Vanguri JD Bocke A Gabriel DF Voytas 1998 Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence Genome Res 8 464 478 1:CAS:528:DyaK1cXjt1aksLY%3D 9582191
20. CW Lawrence DC Hinkle 1996 DNA polymerase zeta and the control of DNA damage induced mutagenesis in eukaryotes Cancer Surv 28 21 31 1:CAS:528:DyaK2sXit1antLg%3D 8977026
21. P Lessage AZ Todeschini 2005 Happy together: the life and times of Ty retrotransposons and their hosts Cytogenet Genome Res 110 70 90 10.1159/000084940
22. A Levina PA Lay 2008 Chemical properties and toxicity of chromium (III) nutritional supplements Chem Res Toxicol 21 563 571 1:CAS:528: DC%2BD1cXhsVSqurg%3D 10.1021/tx700385t 18237145
23. DM Maron B Ames 1983 Revised methods for the Salmonella mutagenicity tests Mutat Res 113 173 215 1:CAS:528:DyaL3sXhvFarsb4%3D 6341825
24. A Morrilon M Springer P Lesage 2000 Activation of the kss1 invasive-filamentous growth pathway induces Ty1 transcription and retrotransposition in Saccharomyces cerevisiae Mol Cell Biol 20 5766 5776 10.1128/MCB.20.15.5766-5776.2000
25. DT Nguyen AM Alarco M Raymond 2001 Multiple Yap1p-binding sites mediate induction of the yeast major facilitator FLR1 gene in response to drugs, oxidants and alkylating agent J Biol Chem 276 1138 1145 1:CAS:528: DC%2BD3MXmtVykuw%3D%3D 10.1074/jbc.M008377200 11056165
26. KM Nyswaner MA Checkley M Yi RM Stephens DG Garfinkel 2008 Chromatin associated genes protect the yeast genome from Ty1 insertional mutagenesis Genetics 178 197 214 1:CAS:528:DC%2BD1cXhs12lsL4%3D 10.1534/genetics.107.082602 18202368
27. CE Paquin VM Williamson 1984 Temperature effect on the role of Ty1 transposition Science 226 53 55 1:CAS:528:DyaL2cXlvVOrsrc%3D 10.1126/science.226.4670.53 17815421
28. CE Paquin VM Williamson 1986 Ty insertions at two loci account for most of the spontaneous antimycinA resistance mutations during growth at 15 degrees C of Saccharomyces cerevisiae strains lacking ADH1 Mol Cell Biol 6 70 79 1:CAS:528:DyaL28Xmtlaqtg%3D%3D 3023838
29. M Pesheva O Krastanova L Staleva M Hadzhitodorov P Venkov 2005 The Ty1 transposition assay: a new short-term test for detection of carcinogens J Microbiol Methods 61 1 8 1:CAS:528:DC%2BD2MXosVGksw%3D%3D 10.1016/j.mimet.2004. 10.001 15676190
30. M Pesheva O Krastanova R Stamenova D Kantardjiev P Venkov 2008 The response of Ty1 test to genotoxins Arch Toxicol 82 779 785 1:CAS:528: DC%2BD1cXht1ehur7I 10.1007/s00204-008-0299-5 18369596
31. MA Rodriguez-Gabrial P Russel 2005 Distinct signaling pathways respond to arsenite and reactive oxygen species in Schizosaccharomyces pombe Eukatyotic Cell 4 1369 1402
32. E Rudolf M Cervinka 2003 Chromium (III) produces distinct type of cell death in cultured cells Acta Medica 46 139 146 1:CAS:528:DC%2BD2cXhsVeltb4%3D 14965163
33. C Sacerdot G Mercier AL Todeschini M Dutreix M Springer P Lesage 2005 Impact of ionizing radiation on the life cycle of Saccharomyces cerevisiae Ty1 retrotransposition Yeast 22 441 455 1:CAS:528:DC%2BD2MXkslemsb8%3D 10.1002/yea.1222 15849797
34. Y Saito K Nishiok Y Yoshida E Niki 2005 Cytotoxic effect of formaldehyde with free radicals via increment of cellular reactive oxygen species Toxicology 210 235 245 1:CAS:528:DC%2BD2MXjsVGrsLs%3D 10.1016/j.tox.2005.02.006 15840437
35. TB Salomon BA Evert B Song PW Doetsch 2004 Biological consequences of oxidative stress-induced DNA damage in Saccharomyces cerevisiae Nucleic Acids Res 32 3712 3722 10.1093/nar/gkh696
36. K Sankavarum BJ Grattan R Walker HJ Park HC Freake 2009 Effects of altered zinc availability on proliferation and oxidative stress in cultured cells FASEB J 23 216.2
37. JG Scandalious 2005 Oxidative stress: molecular perception and transduction of signals triggering antioxidant gene defenses Braz J Med Biol Res 38 995 1014
38. Sherman F, Fink GR, Hicks GB (2001) Methods in yeast genetics: a laboratory manual. Cold Spring Harbor Laboratory Press, Plainview
39. L Staleva P Venkov 2001 Activation of Ty1 transposition by mutagens Mutat Res 474 93 103
40. R Stamenova M Dimitrov T Stoycheva M Pesheva P Venkov Tsvetkov Ts 2008 Transposition of Saccharomyces cerevisiae Ty1 retrotransposon is activated by improper cryopreservation Cryobiology 56 241 247 1:CAS:528:DC%2BD1cXlvF2lt78%3D 10.1016/j.cryobiol.2008.03.007 18466893
41. DW Stephan SL Rivers DJ Jameson 1995 The role of YAP1 and YAP2 genes in the regulation of the adaptive oxidative stress responses of Saccharomyces cerevisiae Mol Microbiol 16 415 423 10.1111/j.1365-2958.1995.tb02407.x
42. T Stoycheva DR Massarado M Pesheva P Venkov K Wolf L Giudice P Pontieri 2007 Ty1 transposition induced by carcinogens in Saccharomyces cerevisiae yeast depends on mitochondrial function Gene 389 212 218 1:CAS:528: DC%2BD2sXht1Gjtbs%3D 10.1016/j.gene.2006.11.009 17208390
43. MW Sutherland BA Learmont 1997 The tetrazolium dyes MTS and XTT provide new quantitative assay for superoxide and superoxide dismutase Free Rad Res 27 283 289 1:CAS:528:DyaK2sXmvFykurc%3D 10.3109/10715769709065766
44. MA Tirmenstein FA Nicolls-Cremski JG Zhang MW Fariss 2000 Glutathione depletion and the production of reactive oxygen species in isolated hepatocyte suspensions Chem Biol Interact. 127 201 217 1:CAS:528:DC%2BD3cXmtVCksrg%3D 10.1016/S0009-2797(00)00180-0 10967318
45. AL Todeschini A Morillon M Springer P Lesage 2005 Severe adenine starvation activates Ty1 transcription and retrotransposition in Saccharomyces cerevisiae Mol Cell Biol 25 7459 7472 1:CAS:528:DC%2BD2MXpsFKhs7k%3D 10.1128/MCB.25.17.7459-7472.2005 16107695
46. T Toyooka Y Ibuki 2007 DNA damage induced by coexposure to PAHs and light Envir Tox Pharm 23 256 263 1:CAS:528:DC%2BD2sXltFSiug%3D%3D 10.1016/j.etap.2006.09.002
47. CL Tucker S Fields 2004 Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress Comp Funct Genomics 5 216 224 1:CAS:528:DC%2BD2cXjvFCis78%3D 10.1002/cfg.391 18629161
48. YARC (1990) Monographs of the evaluation of carcinogenic risks to humans, vol 49. IARC Scientific Publications, YARC, Lyon
49. T Zbigniev P Wojciech 2006 Individual and combined effect of anthracene, cadmium and chloridazone on growth and activity of SOD izoforms in three Scenedesmus species Ecotox Environ Safety 65 323 331 10.1016/j.ecoenv.2005.12. 001
50. JG Zhang FA Nicholls-Crzemski MA Trimenstein MW Fariss 2001 Vitamin E succinate protects hepatocytes against the toxic effect of reactive oxygen species generated at mitochondrial complexes I and III by alkylating agents Chem Biol Interact. 138 267 284 1:CAS:528:DC%2BD3MXosFKlurw%3D 10.1016/S0009- 2797(01)00278-2 11714483
51. L Zhang K Onda R Imai R Fukuda H Horiuchi A Ohta 2003 Growth temperature downshift induces antioxidant response in Saccharomyces cerevisiae Biochem Biophys Res Commun 307 308 314 1:CAS:528:DC%2BD3sXlt1artb0%3D 10.1016/S0006-291X(03)01168-9 12859956