Thrombogenic properties of antiphospholipid antibodies do not depend on their binding to β2 glycoprotein 1 (β2GP1) alone

Lupus

Volumn 7, Issue 5, 1998, Pages 341-346

  Gharavi, A E ^a   Pierangeli, S S ^b   Gharavi, E E ^b   Hua, T ^a   Liu, X W ^b   Barker, J H ^c   Anderson, G H ^c   Harris, E N ^b  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MOREHOUSE SCHOOL OF MEDICINE   (United States)

^c University of Louisville School of Medicine   (United States)

Author keywords

Anti 2GP1 antibodies; Anticardiolipin antibodies; Antiphospholipid syndrome; Lupus anticoagulant; Murine monoclonal antibodies

Indexed keywords

BETA2 GLYCOPROTEIN 1; CARDIOLIPIN ANTIBODY; MONOCLONAL ANTIBODY; PHOSPHOLIPID ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; CONTROLLED STUDY; FEMALE; IMMUNIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; THROMBOGENESIS;

ANIMALS; ANTIBODIES, ANTICARDIOLIPIN; ANTIBODIES, MONOCLONAL; ANTIPHOSPHOLIPID SYNDROME; BETA 2-GLYCOPROTEIN I; BINDING SITES, ANTIBODY; GLYCOPROTEINS; HUMANS; MALE; MICE; THROMBOSIS;

EID: 0031819709     PISSN: 09612033     EISSN: None     Source Type: Journal    
DOI: 10.1191/096120398678920190     Document Type: Article

References (38)

1. Harris EN et al. Anti-cardiolipin antibodies' detection by radioimmunoassay and association with thrombosis. Lancer 1983; ii: 1211-1214.
2. Harris EN, Gharavi AE, Hughes GRV. Anti-phospholipid antibodies. Clin Rheum Dis 1985; 11: 591-609.
3. Hughes GRV, Harris EN, Gharavi AE. The anticardiolipin syndrome. J Rheumatol 1986; 13: 486-489.
4. Lockshin MD et al Antibody to cardiolipin as a predictor of fetal distress or death in pregnant patients with systemic lupus erythematosus. N Engl J Med 1985; 313: 152-156
5. Sammaritano LR, Gharavi AE, Lockshin MD. Antiphospholipid antibody syndrome' immunological and clinical aspects Semin Arthur Rheum 1990; 20: 81-96
6. Harris EN, Pierangeli SS. Antiphospholipid antibodies and antiphospholipid syndrome. Springer Semin Immunopathol 1994; 16: 223-245.
7. 2glycoprotein 1 (apohpoprotein H). Proc Natl Acad Sci USA 1990; 87: 4120-4124.
8. Galli M et al Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor Lancet 1990; 336: 1544-1547
9. Matsuura E, Igarashi Y, Fujimoto M Anticardiolipin antibodies directed not to cardiolipin but to a plasma protein cofactor Lancet 1990; 336: 1547
10. 2glycoprotein 1. J Clin Invest 1992; 1105-1109.
11. 2glycoprotein 1 or anticardiolipin antibodies. Clin Exp Immunol 1993; 93: 269-272
12. 2glycoprotein 1 structure altered by interacting with an oxygen modified solid phase surface. J Exp Med 1994; 179: 457-462.
13. 2glycoprotem 1: a plasma inhibitor of the contact activation of the intrinsic blood coagulation pathway. Blood 1985; 66: 1986-1991.
14. 2glycoprotein 1 Biochem Biophys Acta 1986; 884: 142-144.
15. 2glycoprotein 1 (apo H) inhibits the release reaction of human platelets during ADP-induced aggregation. Atherosclerosis 1987; 63: 109-114.
16. Roubey RAS. Autoantibodies to phospholipid-binding plasma proteins: A new view of lupus anticoagulant and other 'antiphospholipid' autoantibodies. Blood 1994; 84: 2854-2867
17. 2GP1. Am J Reprod Immunot 1997; 37: 118-124.
18. Kohler G, Milstein C. Continuous culture of fused cells secreting antibody to predefined specificity. Nature 1975; 256: 495-497.
19. 2glycoprotein-1 (apolipoprotein H) interaction with phospholipid vesicles. Int J Biochem 1984; 16: 511-515.
20. Exner T. Comparison of two simple tests for the lupus anticoagulant. Am J Clin Pathol 1985; 83: 215-218
21. Stockmans F et al. Continuous quantitative monitoring of mural thrombus kinetics in the crushed rat femoral vein. Thromb Haemost 1991; 65: 425-431.
22. Pierangeli SS et al Effect of human IgG antiphospholipid on an in vivo thrombosis model in mice Thromb Haemost 1994; 71: 670-674.
23. Pierangeli SS et al. Induction of thrombosis in a mouse model by IgG, IgM and IgA immunoglobulins from patients with the Antiphospholipid Syndrome. Thromb Haemost 1995; 74: 1361-1367.
24. 2glycoprotem 1 and human 1 immunoglobulin G antiphospholipid antibodies. Circulation 1996; 94: 1746-1751.
25. 2GP1 and mapping of the gene to chromosome 11. Genomics 1992; 13: 1082-1087.
26. 2glycoprotein-1 molecular analysis of DNA and amino acid polymorphism. Biochem J 1991; 277: 387-391.
27. 2Glycoprotein 1 enhances cardiolipin binding activity but is not the target antigen for antiphospholipid antibodies. Br J Haematol 1992; 82: 565-570.
28. Sammantario LR, Lockshin MD, Gharavi AE. Antiphospholipid antibodies differ in cofactor requirement. Lupus 1992; 1: 51-56.
29. 2glycoprotein 1 antibodies: detection and association with thrombosis. Br J Haematol 1995; 89: 397-402.
30. 0 J Lab Clin Med 1993; 122: 426-431.
31. Harris EN, Pierangeli SS, Barquinero J, Ordi Ros J. Anticardiolipin antibodies and binding of anionic phospholipids and scrum proteins Lancet 1990; 336: 505-506.
32. Simantov R et al. Activation of Cultural Vascular Endothelial Cells by Antiphospholipid Antibodies. J Clin Invest 1995; 96: 2211-2219.
33. Del Papa N et al Characterization of anti-endothelial cell antibodies in antiphospholipid syndrome. In: Molecular Basis of Human Diseases Polli EE (ed.) Elsevier Science Publishers: Amsterdam, pp 67-73.
34. 2glycoprotein 1. Thromb Haemost 1993; 70: 336-341
35. 2glycoprotein 1. Br J Haematol 1995; 87: 548.
36. McCrae KR et al. Detection of anti-endothehal cell reactive immunoglobulin in patients with anti-phospholipid antibodies. Br J Haematol 1991; 79: 595-605.
37. Campbell AE, Pierangeli SS, Wellhausen S, Harris EN. Comparison of the effect of anticardiolipin antibodies from patients with the antiphospholipid syndrome and with syphilis on platelet activation and aggregation. Thromb Haemost 1995; 73: 519-524
38. 2glycoprotein-l concentration in human serum Humangenetik 1969; 9: 93-97.