Analysis of gene expression in the testes of mice exposed to bisphenol a and nonylphenol

Biochip Journal

Volumn 3, Issue 1, 2009, Pages 12-20

  Oh, Jung Hwa ^a   Oh, Moon Ju ^b   Park, Han Jin ^a   Kim, Seung Jun ^b   Park, Se Myo ^a   Yoon, Hea Jin ^a   Cho, Jae Woo ^c   Hwang, Seung Yong ^b   Yoon, Seokjoo ^a  

^a Toxicogenomics Team ^*  (South Korea)

^b GenoCheck Co Ltd   (South Korea)

^c Korea Institute of Toxicology   (South Korea)

Author keywords

Bisphenol a; Gene expression profiling; Nonylphenol; Reproductive toxicity; Xenoestrogens

Indexed keywords

CLUSTERING ALGORITHMS; PHENOLS; SIGNALING; TOXICITY;

BISPHENOL A; GENE EXPRESSION PROFILING; NONYLPHENOLS; REPRODUCTIVE TOXICITY; XENOESTROGENS;

GENE EXPRESSION;

MUS;

EID: 79251578325     PISSN: 19760280     EISSN: 20927843     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Danzo, B.J. Environmental xenobiotics may disrupt normal endocrine function by interfering with the binding of physiological ligands to steroid receptors and binding proteins. Environ. Health Perspect. 105, 294 -301 (1997).
2. White, R., Jobling, S., Hoare, S.A., Sumpter, J.P. & Parker, M.G. Environmentally persistent alkylphenolic compounds are estrogenic. Endocrinology 135, 175-182 (1994).
3. Clark, J.H., Schrader, W.T. & O'Malley, B.W. Mechanism of action of steroid hormone. TEXTBOOK of ENDOCRINOLOGY pp. 35-90 (1992).
4. Hess, R.A. et al. A role for oestrogens in the male reproductive system. Nature 390, 509-512 (1997).
5. Hess, R.A. et al. Estrogen receptor (alpha and beta) expression in the excurrent ducts of the adult male rat reproductive tract. J. Androl. 18, 602-611 (1997).
6. Sharpe, R.M. Do males rely on female hormones? Nature 390, 447-448 (1997).
7. Asklund, C., Jørgensen, N., Kold-Jensen, T. & Skakke-baek, N.E. Biology and epidemiology of testicular dysgenesis syndrome. BJU Int. 93, 6-11 (2004).
8. Gray, L.E. et al. Administration of potentially anti-androgenic pesticides (procymidone, linuron, iprodi-one, chlozolinate, p,p′-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual differentiation produces diverse profiles of reproductive malformations in the male rat. Toxicol. Ind. Health 15, 94-118 (1999).
9. Traina, M.E. et al. Long-lasting effects of lindane on mouse spermatogenesis induced by in utero exposure. Reprod. Toxicol. 17, 25-35 (2003).
10. Hess, R.A. Effects of environmental toxicants on the efferent ducts, epididymis and fertility. J. Reprod. Fertil. Suppl. 53, 247-259 (1998).
11. Chung, H. et al. Comprehensive analysis of differential gene expression profiles on carbon tetrachloride-induced rat liver injury and regeneration. Toxicol. Appl. Pharmacol. 206, 27-42 (2004).
12. Lim, J.S. et al. Effects of phalloidin on hepatic gene expression in mice. Int. J. Toxicol. 26, 213-220 (2007).
13. Oda, H. et al. Microarray analysis of the genes induced by tetracycline-regulated expression of NDRF/ NeuroD2 in P19 cells. Biochem. Biophys. Res. Com-mun. 335, 458-468 (2005).
14. Powell, C.L. et al. Phenotypic anchoring of aceta-minophen-induced oxidative stress with gene expression profiles in rat liver. Toxicol. Sci. 93, 213-222 (2006).
15. Naciff, J.M. et al. Gene expression changes induced in the testis by transplacental exposure to high and low doses of 17{alpha}-ethynyl estradiol, genistein, or bisphenol A. Toxicol. Sci. 86, 396-416 (2005).
16. Kato, N. et al. Gene expression profile in the livers of rats orally administered ethinylestradiol for 28 days using a microarray technique. Toxicology 200, 179-192 (2004).
17. Boverhof, D.R. et al. Temporal- and dose-dependent hepatic gene expression changes in immature ovari-ectomized mice following exposure to ethynyl estra-diol. Carcinogenesis 25, 1277-1291 (2004).
18. Maras, M. et al. Estrogen-like properties of fluorote-lomer alcohols as revealed by mcf-7 breast cancer cell proliferation. Environ. Health Perspect. 114, 100 -105 (2006).
19. Wang, D.Y., Fulthorpe, R., Liss, S.N. & Edwards, E.A. Identification of estrogen-responsive genes by complementary deoxyribonucleic acid microarray and characterization of a novel early estrogen-induced gene: EEIG1. Mol. Endocrinol. 18, 402-411 (2004).
20. Buterin, T., Koch, C. & Naegeli, H. Convergent transcriptional profiles induced by endogenous estrogen and distinct xenoestrogens in breast cancer cells. Carcinogenesis 27, 1567-1578 (2006).
21. Takamiya, M., Lambard, S. & Huhtaniemi, I.T. Effect of bisphenol A on human chorionic gonadotrophin-stimulated gene expression of cultured mouse Leydig tumour cells. Reprod. Toxicol. 24, 265-275 (2007).
22. Tabuchi, Y., Zhao, Q.L. & Kondo, T. DNA micro-array analysis of differentially expressed genes responsive to bisphenol A, an alkylphenol derivative, in an in vitro mouse Sertoli cell model. Jpn. J. Pharmacol. 89, 413-416 (2002).
23. Al-Hiyasat, A.S., Darmani, H. & Elbetieha, A.M. Effects of bisphenol A on adult male mouse fertility. Eur. J. Oral. Sci. 110, 163-167 (2002).
24. Zha, J., Wang, Z., Wang, N. & Ingersoll, C. Histolo-gical alternation and vitellogenin induction in adult rare minnow (Gobiocypris rarus) after exposure to ethynylestradiol and nonylphenol. Chemosphere 66, 488-495 (2007).
25. Kyselova, V., Peknicova, J., Buckiova, D. & Boube-lik, M. Effects of p-nonylphenol and resveratrol on body and organ weight and in vivo fertility of outbred CD-1 mice. Reprod. Biol. Endocrinol. 1, 1-10 (2003).
26. Tyl, R.W. et al. Three-generation reproductive toxi-city study of dietary bisphenol A in CD Sprague-Dawley rats. Toxicol. Sci. 68, 121-146 (2002).
27. Ema, M. et al. Rat two-generation reproductive toxi-city study of bisphenol A. Reprod. Toxicol. 15, 505-523 (2001).
28. Kwon, S., Stedman, D.B., Elswick, B.A., Cattley, R.C. & Welsch, F. Pubertal development and reproductive functions of Crl: CD BR Sprague-Dawley rats exposed to bisphenol A during prenatal and postnatal development. Toxicol. Sci. 55, 399-406 (2000).
29. Takao, T. et al. Exposure with the environmental estrogen bisphenol A disrupts the male reproductive tract in young mice. Life Sci. 65, 2351-2357 (1999).
30. Tohei, A., Suda, S., Taya, K., Hashimoto, T. & Kogo, H. Bisphenol A inhibits testicular functions and increases luteinizing hormone secretion in adult male rats. Exp. Biol. Med. 226, 216-221 (2001).
31. Sakaue M. et al. Bisphenol-A affects spermatogenesis in the adult rat even at a low dose. J. Occup. Health 43, 185-190 (2001).
32. Takahashi, O. & Oishi, S. Testicular toxicity of die-tarily or parenterally administered bisphenol A in rats and mice. Food Chem. Toxicol. 41, 1035-1044 (2003).
33. Petersen, C., Fuzesi, L. & Hoyer-Fender, S. Outer dense fibre proteins from human sperm tail: molecular cloning and expression analyses of two cDNA transcripts encoding proteins of approximately 70 kDa. Mol. Hum. Reprod. 5, 627-635 (1999).
34. Tsai-Morris, C.H., Sheng, Y., Lee, E., Lei, K.J. & Dufau, M.L. Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is essential for spermatid development and completion of spermatogenesis. Proc. Natl. Acad. Sci. USA 101, 6373-6378 (2004).
35. Osaki, E. et al. Identification of a novel Sry-related gene and its germ cell-specific expression. Nucleic Acids Res. 27, 2503-2510 (1999).
36. Kanai, Y. et al. Identification of two Sox17 messenger RNA isoforms, with and without the high mobility group box region, and their differential expression in mouse spermatogenesis. J. Cell Biol. 133, 667-681 (1996).
37. Denny, P., Swift, S., Connor, F. & Ashworth, A. An SRY-related gene expressed during spermatogenesis in the mouse encodes a sequence-specific DNA-binding protein. EMBO J. 11, 3705-3712 (1992).
38. Kuhlbrodt, K. et al. Cooperative function of POU proteins and SOX proteins in glial cells. J. Biol. Chem. 273, 16050-16057 (1998).
39. Kinoshita, Y. & Chen, S. Induction of aromatase (CYP19) expression in breast cancer cells through a nongenomic action of estrogen receptor alpha. Cancer Res. 63, 3546-3555 (2003).
40. Masuyama, H., Hiramatsu, Y., Kunitomi, M., Kudo, T. & MacDonald, P.N. Endocrine disrupting chemicals, phthalic acid and nonylphenol, activate Pregnane X receptor-mediated transcription. Mol. Endocrinol. 14, 421-428 (2000).
41. El-Dakdoky, M.H. & Helal, M.A. Reproductive toxi-city of male mice after exposure to nonylphenol. Bull. Environ. Contam. Toxicol. 79, 188-191 (2007).
42. Kouzmenko, A.P. et al. Wnt/beta-catenin and estrogen signaling converge in vivo. J. Biol. Chem. 279, 40255-40258 (2004).