Regulation of pendrin by pH: Dependence on glycosylation

Biochemical Journal

Volumn 434, Issue 1, 2011, Pages 61-72

  Azroyan, Anie ^a   Laghmani, Kamel ^a   Crambert, Gilles ^a   Mordasini, David ^a   Doucet, Alain ^a   Edwards, Aurélie ^a,b  

^a SORBONNE UNIVERSITÉ   (France)

^b Tufts University   (United States)

Author keywords

Anion exchanger; Glycosylation; Mathematical modelling; Pendrin; pH homoeostasis; Transport kinetics

Indexed keywords

ANION; CARBONIC ACID; CHLORIDE; HYDROXIDE; PENDRIN; PROTON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANION EXCHANGE; APICAL MEMBRANE; ARTICLE; BINDING AFFINITY; CELL ACTIVITY; CELL PH; CELL POLARITY; CELL STRAIN HEK293; CELL SURFACE; CONTROLLED STUDY; GENE DISRUPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; ION EXCHANGE; KIDNEY PROXIMAL TUBULE; MATHEMATICAL MODEL; MOUSE; NONHUMAN; OPOSSUM; PH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN TARGETING; REGULATORY MECHANISM; SITE DIRECTED MUTAGENESIS; TRANSPORT KINETICS;

ANIMALS; ANION TRANSPORT PROTEINS; CELL LINE; CHLORIDES; CLONING, MOLECULAR; GLYCOSYLATION; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROXYL RADICAL; KINETICS; MICE; MUTAGENESIS, SITE-DIRECTED; OPOSSUMS;

DIDELPHIDAE;

EID: 79251556536     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20101411     Document Type: Article

References (46)

1. Reardon, W. and Trembath, R. C. (1996) Pendred syndrome. J. Med. Genet. 33, 1037-1040
2. Kraiem, Z., Heinrich, R., Sadeh, O., Shiloni, E., Nassir, E., Hazani, E. and Glaser, B. (1999) Sulfate transport is not impaired in Pendred syndrome thyrocytes. J. Clin. Endocrinol. Metab. 84, 2574-2576
3. Royaux, I. E., Suzuki, K., Mori, A., Katoh, R., Everett, L. A., Kohn, L. D. and Green, E. D. (2000) Pendrin, the protein encoded by the Pendred syndrome gene ( PDS), is an apical porter of iodide in the thyroid and is regulated by thyroglobulin in FRTL-5 cells. Endocrinology 141, 839-845
4. Scott, D. A. and Karniski, L P. (2000) Human pendrin expressed in Xenopus laevisoocytes mediates chloride/formate exchange. Am. J. Physiol. Cell Physiol. 278, C207-C211
5. Kopp, P., Pesce, L. and Solis, S, J. C. (2008) Pendred syndrome and iodide transport in the thyroid. Trends Endocrinol. Metab. 19, 260-268
6. Maciaszczyk, L. and Lewinski, A. (2008) Phenotypes of SLC26A4 gene mutations: Pendred syndrome and hypoacusis with enlarged vestibular aqueduct. Neuroendocrinol. Lett. 29, 29-36
7. Rillema, J. A. and Hill, M. A. (2003) Prolactin regulation of the pendrin-iodide transporter in the mammary gland. Am. J. Physiol. Endocrinol. Metab. 284, E25-E28
8. Suzuki, K., Royaux, I. E., Everett, L. A., Mori-Aoki, A., Suzuki, S., Nakamura, K., Sakai, T., Katoh, R., Toda, S., Green, E. D. and Kohn, L. D. (2002) Expression of PDS/ Pds, the Pendred syndrome gene, in endometrium. J. Clin. Endocrinol. Metab. 87, 938
9. Bidart, J.-M., Lacroix, L., Evain-Brion, D., Caillou, B., Lazar, V., Frydman, R., Bellet, D., Filetti, S. and Schlumberger, M. (2000) Expression of Na+/I-symporter and Pendred syndrome genes in trophoblast cells. J. Clin. Endocrinol. Metab. 85, 4367-4372
10. Royaux, I. E., Wall, S. M., Karniski, L. P., Everett, L. A., Suzuki, K., Knepper, M. A. and Green, E. D. (2001) Pendrin, encoded by the Pendred syndrome gene, resides in the apical region of renal intercalated cells and mediates bicarbonate secretion. Proc. Natl. Acad. Sci. U.S.A. 98, 4221-4226
11. Wall, S. M., Kim, Y. H., Stanley, L., Glapion, D. M., Everett, L. A., Green, E. D. and Verlander, J. W. (2004) NaCl restriction upregulates renal Slc26a4 through subcellular redistribution: role in Cl- conservation. Hypertension 44, 982-987
12. Verlander, J. W., Hassell, K. A., Royaux, I. E., Glapion, D. M., Wang, M.-E., Everett, L. A., Green, E. D. and Wall, S. M. (2003) Deoxycorticosterone upregulates PDS (Slc26a4) in mouse kidney: role of pendrin in mineralocorticoid-induced hypertension. Hypertension 42, 356-362
13. - exchanger pendrin in the rat kidney is regulated in response to chronic alterations in chloride balance. Am. J. Physiol. Renal Physiol. 287, F1179-F1188
14. Vallet, M., Picard, N., Loffing-Cueni, D., Fysekidis, M., Bloch-Faure, M., Deschenes, G., Breton, S., Meneton, P., Loffing, J., Aronson, P. S. et al. (2006) Pendrin regulation in mouse kidney primarily is chloride-dependent. J. Am. Soc. Nephrol. 17, 2153-2163
15. Leviel, F., Hubner, C. A., Houillier, P., Morla, L., El Moghrabi, S., Brideau, G., Hatim, H., Parker, M. D., Kurth, I., Kougioumtzes, A. et al. (2010) The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice. J. Clin. Invest. 120, 1627-1635
16. - flux in extrarenal epithelia. Proc. Natl. Acad. Sci. U.S.A. 101, 2064-2069
17. Schambelan, M., Sebastian, A. and Rector, Jr, F. C. (1981) Mineralocorticoid-resistant renal hyperkalemia without salt wasting (type II pseudohypoaldosteronism): role of increased renal chloride reabsorption. Kidney Int. 19, 716-727 (Pubitemid 11064677)
18. Take, C., Ikeda, K., Kurasawa, T. and Kurokawa, K. (1991) Increased chloride reabsorption as an inherited renal tubular defect in familial type II pseudohypoaldosteronism. N. Eng. J. Med. 324, 472-476
19. Yamauchi, K., Rai, T., Kobayashi, K., Sohara, E., Suzuki, T., Itoh, T., Suda, S., Hayama, A., Sasaki, S. and Uchida, S. (2004) Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins. Proc. Natl. Acad. Sci. U.S.A. 101, 4690-4694
20. - /anion exchanger pendrin in mouse kidney by acid-base status. Kidney Int. 62, 2109-2117
21. Knauf, F., Yang, C.-L., Thomson, R. B., Mentone, S. A., Giebisch, G. and Aronson, P. S. (2001) Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells. Proc. Natl. Acad. Sci. U.S.A. 98, 9425-9430
22. - exchanger in the kidney cortex. Am. J. Physiol. Renal Physiol. 280, F356-F364
23. - secretion and in regulation of CFTR in the parotid duct. J. Physiol. 586, 3813-3824
24. Weinstein, A. M. (2000) A mathematical model of the outer medullary collecting duct of the rat. Am. J. Physiol. Renal Physiol. 279, F24-45
25. Royaux, I., Belyantseva, I., Wu, T., Kachar, B., Everett, L., Marcus, D. and Green, E. (2003) Localization and functional studies of pendrin in the mouse inner ear provide insight about the etiology of deafness in Pendred syndrome. J. Assoc. Res. Otolaryngol. 4, 394-404
26. Scott, D. A., Wang, R., Kreman, T. M., Scheffield, V. C. and Karniski, L. P. (1999) The Pendred syndrome gene encodes a chloride-iodide transport protein. Nat. Genet. 21, 440-443
27. Schuster, V. L. (1991) Cortical collecting duct bicarbonate secretion. Kidney Int. Suppl. 33, S47-S50
28. Schuster, V. L. (1986) Cyclic adenosine monophosphate-stimulated anion transport in rabbit cortical collecting duct. Kinetics, stoichiometry and conductive pathways. J. Clin. Invest. 78, 1621-1630
29. Garcia-Austt, J., Good, D. W., Burg, M. B. and Knepper, M. A. (1985) Deoxycorticosterone-stimulated bicarbonate secretion in rabbit cortical collecting ducts: effects of luminal chloride removal and in vivo acid loading. Am. J. Physiol. Renal Physiol. 249, F205-F212
30. Gasbjerg, P. K., Knauf, P. A. and Brahm, J. (1996) Kinetics of bicarbonate transport in human red blood cell membranes at body temperature. J. Gen. Physiol. 108, 565-575
31. Knauf, P. A., Gasbjerg, P. K. and Brahm, J. (1996) The asymmetry of chloride transport at 38°C in human red blood cell membranes. J. Gen. Physiol. 108, 577-589
32. Knauf, P. A., Law, F.-Y., Leung, T.-W. V., Gehret, A. U. and Perez, M. L. (2002) Substrate-dependent reversal of anion transport site orientation in the human red blood cell anion-exchange protein, AE1. Proc. Natl. Acad. Sci. U.S.A. 99, 10861-10864
33. Garlick, P. B., Radda, G. K. and Seeley, P. J. (1979) Studies of acidosis in the ischaemic heart by phosphorus nuclear magnetic resonance. Biochem. J. 184, 547-554
34. Sterling, D. and Casey, J. R. (1999) Transport activity of AE3 chloride/bicarbonate anion-exchanger proteins and their regulation by intracellular pH. Biochem. J. 344, 221-229
35. Humphreys, B. D., Jiang, L., Chernova, M. N. and Alper, S. L. (1994) Functional characterization and regulation by pH of murine AE2 anion exchanger expressed in Xenopus oocytes. Am. J. Physiol. Cell Physiol. 267, C1295-C1307
36. Zhang, Y., Chernova, M. N., Stuart-Tilley, A. K., Jiang, L. and Alper, S. L. (1996) The cytoplasmic and transmembrane domains of AE2 both contribute to regulation of anion exchange by pH. J. Biol. Chem. 271, 5741-5749
37. + reabsorption in a Pendred syndrome mouse model. Am. J. Physiol. Renal Physiol. 292, F1345-F1353
38. Everett, L. A., Morsli, H., Wu, D. K. and Green, E. D. (1999) Expression pattern of the mouse ortholog of the Pendred's syndrome gene ( Pds) suggests a key role for pendrin in the inner ear. Proc. Natl. Acad. Sci. U.S.A. 96, 9727-9732
39. Couloigner, V., Teixeira, M., Hulin, P., Sterkers, O., Bichara, M., Escoubet, B., Planelles, G. and Ferrary, E. (2000) Effect of locally applied drugs on the pH of luminal fluid in the endolymphatic sac of guinea pig. Am. J. Physiol. Regul. Integr. Comp. Physiol. 279, R1695-R1700
40. Tsujikawa, S., Yamashita, T., Amano, H., Kumazawa, T. and Vosteen, K. H. (1992) Acidity in the endolymphatic sac fluid of guinea pigs. J. Otorhinolaryngol. Relat. Spec. 54, 198-200
41. Asano, T., Takata, K., Katagiri, H., Ishihara, H., Inukai, K., Anai, M., Hirano, H., Yazaki, Y. and Oka, Y. (1993) The role of N-glycosylation in the targeting and stability of GLUT1 glucose transporter. FEBS Lett. 324, 258-261
42. Fishburn, C. S., Elazar, Z. and Fuchs, S. (1995) Differential glycosylation and intracellular trafficking for the long and short isoforms of the D dopamine receptor. J. Biol. Chem. 270, 29819-9824
43. - cotransporter. J. Am. Soc. Nephrol. 14, 271-282
44. - transport. Am. J. Physiol. Renal Physiol. 290, F1094-F1102
45. Pocker, Y. and Bjorkquist, D. W. (1977) Stopped-flow studies of carbon dioxide hydration and bicarbonate dehydration in water and water-d2. Acid-base and metal ion catalysis. J. Am. Chem. Soc. 99, 6537-6543
46. Weinstein, A. M. (2010) A mathematical model of rat ascending Henle limb. I. Cotransporter function. Am. J. Physiol. Renal Physiol. 298, F512-F524