Exopolysaccharides as promising biomaterials for pharmaceutical applications: A review

Indian Drugs

Volumn 47, Issue 9, 2010, Pages 7-22

  Manjanna, K M ^a   Shivakumar, B ^a   Pramodkumar, T M ^a  

^a NONE

Author keywords

Biodegradability; Biomaterials; Exopolysaccharides; Gelling agents; Release modifiers

Indexed keywords

ALGINIC ACID; BIOMATERIAL; CARRAGEENAN; EXOPOLYSACCHARIDE; GELATIN; GELLAN; GELLING AGENT; INTERFERON; NANOPARTICLE; PULLULAN; QUANTUM DOT; SCLEROGLUCAN; XANTHAN;

BIOCOMPATIBILITY; CANCER THERAPY; CHEMICAL STRUCTURE; COSMETIC INDUSTRY; DIAGNOSTIC IMAGING; DRUG DOSAGE FORM; FLOW KINETICS; FOOD INDUSTRY; GENE TARGETING; HYDROCOLLOID; IMMOBILIZED CELL; MELTING POINT; PH; PHYSICAL CHEMISTRY; REVIEW; SOLUBILITY; THERMOSTABILITY; TISSUE ENGINEERING; WOUND HEALING;

EID: 79251512021     PISSN: 0019462X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (53)

1. Hoffman A.S.: Hydrogels for biomedical applications, Adv Drug Deliv Rev. 2002; 54; 3-12.
2. Franz G., Hensel A., Kraus J.: Biomedical and Biotechnological advances in industrial polysaccharides, Macromol. 1989; 22,1863-1865.
3. Peppas N.A., Bures P., Leobandung W., Ichikawa. H.: Hydrogels in pharmaceutical formulations, Eur J Biopharm. 2000; 50; 27-46.
4. Sutherland I. W.: Microbial exopolysaccharides - structural subtleties and their consequences, Pure & Appl Chem. 1997; 69(9); 1911-1917. (Pubitemid 127485007)
5. Margaritis, Pace G.W.: Microbial polysaccharides, Adv Biotechnol. 1985;2; 1005-1044.
6. Sandford P.A.: Extracellular microbial polysaccharides, Adv Carbohydr Chem Biochem. 1979; 36; 265-312.
7. Clark A.H., Ross-Murphy S.B.: Structural and mechanical properties of biopolymer gels, Adv Polym Sci. 1987; 83; 57-92.
8. Survase S.A. et al: Fermentative production of scleroglucan: Food Technol Biotechnol. 2007; 45(2); 107-118.
9. Coviello T. et al : Scleroglucan: A Versatile polysaccharide for modified drug delivery, Mol. 2005; 10; 6-33.
10. Pirri R., Gadioux J., Riveno R.: Scleroglucan gel applied to the oil industry U.S. Patent 3447, 940. 1969.
11. Halleck F.E.: Cosmetic Composition containing a polysaccharide U.S. Patent 3,659, 025, 1972.
12. Sheth P., Lachman L.: The Coating of Tablets. Fr. Patent 1, 480, 874, 1967.
13. San-Ei Chemical industries, Ltd. Improvement of frozen food quality with Sclerogum, Japan Kokai Tokkyo Koho 57, 163, 451, 1982.
14. Singh P., Wilser R., Tokuzen R., Nakahara W.: Scleroglucan an antitumour polysaccharide from Sclerotium glucanicum, Carbohyd Res. 1974; 37; 245.
15. Jong S., Donovick R.: Antitumour and Antiviral substances from fungi, Adv Appl Microbiol. 1989; 34; 183-189.
16. Brigand G.: Scleroglucan, Industrial Gums: Academic press, Newyork USA 1993; 461-472.
17. Pretus H.A., Ensley H.E., Mc Namec R.B., Jones E.L.: Isolation, Physicochemical Characterization and Preclinical efficacy evaluation of soluble scleroglucan. J Pharmacol Exp Ther. 1991; 257; 500-510.
18. Coviello T., Dentini M., Crescenzi V.: Conformation and Thermal Stability of oxidized scleroglucan chains in aqueous NaOH, Polym Bull. 1995, 34; 337-343.
19. Farina J.I., Sineriz F., Molina O.E., Perotti N.I.: Isolation and Physicochemical Characterization of soluble scleroglucan from Sclerotium rolfsii-Rheological properties, molecular weight and conformational characteristics, Carbohydr Polym. 2001; 44(1); 41-50. (Pubitemid 33375925)
20. Rodgers: Scleroglucan; Industrial Gums Academic press, Newyork USA 1993; 461-472.
21. Coviello T. et al : Novel hydrogel systems from scleroglucan; synthesis and characterization, J Control Rel. 1999; 60; 367-378.
22. Sheth P., Lachman L. : The Coating tablets. FR. Patent 1, 480, 874, 1967.
23. Coviello T. et al : A Versatile polysaccharide for modified drug delivery, Mol. 2005; 10; 6-33.
24. Rizk. S. et al : Physico-chemical characterization and tableting properties of Scleroglucan, Int J Pharm. 1994; 112; 125-130.
25. Coviello T. et al: A novel Cross-linked polysaccharide; Studies for a controlled delivery matrix, J Control Rel. 1998; 55; 57-63.
26. Marchetti et al: Antiviral effect of polysaccharide from Sclerotium glucanicum towards herpes simplex virus type I infection, Plant Med. 1996; 62; 303-308.
27. nd Edition. Wiley & Sons New York 1988; 650.
28. Leather T.D.: Fungal exopolysaccharides, Appl. Microbiol Biotechnol. 2003; 62; 468-473.
29. Akiyoshi A. et al : Self-assembled hydrogel nanoparticles of cholesterol bearing pullulan as a Carrier of protein drugs; Complexation and stabilization of insulin, J Control Rel. 1998; 54; 313-320.
30. Jeong Y., Nah J.W., Na K, Cho C.S., Kim S.H.: Self assembled nanospheres of hydrophobized pullulans in water, Drug Dev Ind Pharm. 1999; 25; 917-927.
31. Hasuda T. et al : Macromolecular Complexation between bovine serum albumin and the self-assembled hydrogel nanoparticles of hydrophobized polysaccharides, J Am Chem Soc 1996; 118; 6110-6115.
32. Akiyoshi K., Kang E.C., Kuromada S., Winnik F.M.: Controlled association of amphiphilic polymers in water; thermosensitive nonoparticles formed by self-assembly of hydrobhobically modified pullulans, Macromol. 2000; 33; 3244-3249.
33. Gupta M., Gupta A.K.: Hydrogel pullulan nonoparticles encapsulating PBUD Lacz plasmid as an efficient gene delivery carrier, J Control Rel. 2004; 99; 157-166.
34. Shingel K.I., Petrov P.T.: Supramolecular assembly between nanoparticles of hydrophobized polysaccharide and soluble protein complexation between the self-aggregate of cholesterol-bearing pullulan and alphachymotrypsin, Macromol. 1994; 27; 7654-7659.
35. Nomura et al: Molecular chaperone like activity of hydrogel nanoparticles of hydrophobized pullulan; thermal stabilization with refolding of carbonic anhydrase B, Bioconjug Chem. 1999; 10; 321-324.
36. Morimoto N., Endo T., Iwasaki Y., Akiyoshi K.: Design of hybrid hydrogels with self-assembled nanogels as cross-linkers; Interaction with proteins and chaperone-like activity; Biomacromol. 2005; 6; 1829-1834.
37. Kaneo N. et al: Self-assembled hydrogel nonoparticles of cholesterol-bearing pullulan as a carrier of protein drugs, J Control Rel. 1998; 54; 313-325.
38. Lec I., Akiyoshi K.: Single molecular mechanics of cholesterol-bearing pullulan nonogel at the hydrophobic interfaces, Biomat. 2004; 24; 2911-2918.
39. Akiyoshi K., Nishikawa T., Shichibe S., Sunamoto J.: Stabilization of Insulin upon supramolecular complexation with hydrophobized polysaccharide nanoparticles, Chem Lett. 1995; 8; 707-708.
40. Nogusa. K., Bae Y. H.: Self-assembled hydrogel nanoparticles responsive to tumour extracellular pH from pullulan derivative/sulphonamide conjugate; characterization, aggregation and adriamycin release in vivo, Pharm Res. 2002; 19; 681-688.
41. Na K., Seong-Lee, Bae Y.H.: Adriamycin loaded pullulan acetate/sulfonamide conjugate nanoparticles responding to tumor pH dependent cell interaction; internalization & cytotoxicity in vitro, J Control Rel. 2003; 87; 3-13. (Pubitemid 36255443)
42. Laura De Laporte et al: Design of Modular non-viral gene therapy vectors, Acta Pharm. 2007; 57; 249-268.
43. Hosseinkhani N. et al: Associate pullulan gels and their interaction with biological active substances, J Control Rel. 2002; 83; 41-51.
44. Hasegawa et al: Hybrid nanogels with physical and Chemical Cross-linking structures as nanocarriers, Macromol Biosci. 2005; 5; 710-716.
45. Coviello T., Matricardi P., Marianecci C., Altiaique F.: Polysaccharide hydrogels for modified release formulations, J Control Rel. 2007; 119; 5-24. (Pubitemid 46561537)
46. Carlfors J., Edsman K., Petersson R., Jornving K., Rheological evaluation of Gelrite® in situ gels for ophthalmic use, Eur J Pharm Sci. 1998; 6; 113-119. (Pubitemid 28164281)
47. Paulsson M., Hagerstrom H., Edsman K.: Rheological studies of the gelation of deacetylated gellan gum in physiological conditions, Eur J Pharm Sci. 1999; 9; 90-105.
48. Jansson B. et al: The influence of gellan gum on the transfer of fluorescein dextran across rat nasal epithelium in vivo, Eur J Pharm Biopharm. 2005; 59; 557-564.
49. Fujii T., Ogiwara D., Ohkawa K., Yamamoto H.: Alkaline Phosphate encapsulated in gellan-chitosan hybrid capsules, Macromol Biosci. 2005; 5; 394-400.
50. Singh B.N., Kim K.H.: Effects of divalent cations on drug encapsulation efficiency of deacylated gellan gum, J Microencapsul. 2005; 22; 761-771.
51. Miyazaki S. et al: In situ - gelling gelan formulations as vehicles for oral drug delivery, J Control Rel. 1999; 60; 287-295. (Pubitemid 29335954)
52. Santucci E. et al: Gellan for the formulation of sustained delivery beads, J Control Rel. 1996; 42; 157-164.
53. Agnihotri S.A., Aminabhavi T.M.: Development of novel interpenetrating network gellan gum-poly (vinylalcohol) hydrogel microspheres for the controlled release of carvedilos, Drug Dev Ind Pharm. 2005; 31; 491-503.