Gellan for the formulation of sustained delivery beads

Journal of Controlled Release

Volumn 42, Issue 2, 1996, Pages 157-164

  Santucci, E ^a   Alhaique, F ^a   Carafa, M ^a   Coviello, T ^a   Murtas, E ^a   Riccieri, F M ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Alginate beads; Gellan beads; Polysaccharides; Sustained release

Indexed keywords

ALGINIC ACID; BENZAMIDE; GELLAN; OIL; POLYMER; SURFACTANT; THEOPHYLLINE;

ARTICLE; CLAY; DISSOLUTION; DRUG FORMULATION; DRUG RELEASE; PRIORITY JOURNAL; SUSTAINED RELEASE PREPARATION;

EID: 0030296098     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-3659(96)01373-9     Document Type: Article

References (22)

1. [1] P. Buri and E. Doelker, Formulation des comprimés à libération prolongée. II. Matrices hydrophiles. Pharm. Acta Helv. 55 (1980) 189-197.
2. [2] C.D. Melia, Hydrophilic matrix sustained release systems based on polysaccharides carriers. Crit. Rev. Ther. Drug Carr. Syst. 8 (1991) 395-421.
3. [3] D. Bonadeo, C. Caramella, R. Cantoni, A. Fiori, E. Formica, P. Furlani, A. Gazzaniga, D. Lombardi, A. Martini, R. Orlandi and G. Sala, Caratterizzazione di materiali polimerci per il rilascio modificato di farmaci e utilizzo di miscele di polimeri idrofili gelificabili. Boll. Chim. Farm. 133 (1994) 599-604.
4. [4] A.B. Pepperman and J.W. Kuan, Slow release formulation of metribuzin based on alginate-kaolin-linseed oil. J. Control. Release 26 (1993) 21-30.
5. [5] H. Grasdalen and O. Smidsroed, Gelation of gellan gum. Carbohydr. Polym. 7 (1987) 371-393.
6. [6] V. Crescenzi, M. Dentini and T. Coviello, Solution and gelling properties of microbial polysaccharides of industrial interest: the case of gellan. NATO ASI Ser., Ser. E (Novel Biodegrad. Microb. Polym.) (1990) 227-284.
7. [7] G.R. Sanderson and R.C. Clark, Gellan gum, a new swelling polysaccharide, in Gums and Stabilizers for the Food Industry 2, Pergamon Press, Oxford, 1984, pp. 201-210.
8. [8] D.M.W. Anderson, W.G. Brydon and M.A. Eastwood, The dietary effects of gellan in humans. Food Addit. Contam. 5 (1988) 237-249.
9. [9] A. Rozier, C. Mazuel, J. Grove and B. Plazonnet, Gelrite: a novel, ion-activated, in-situ gelling polymer for ophtalmic vehicles. Effect on bioavailability of timolol. Int. J. Pharm. 57 (1989) 163-168.
10. [10] P.B. Deasy and K.J. Quigley, Rheological evaluation of deacetilated gellan gum (Gelrite) for pharmaceutical use. Int. J. Pharm. 57 (1991) 117-123.
11. [11] Y.D. Sanzgiri, S. Maschi, V. Crescenzi, L. Callegaro, E.M. Topp and V.J. Stella, Gellan-based system for ophthalmic sustained delivery of methylprednisolone. J. Control. Release 26 (1993) 195-201.
12. [12] A.B. Pepperman and J.W. Kuan, HPLC and GC/MS of metribuzin and its degradation products from alginate-linseed oil controlled release formulation. J. Liq. Chromatogr. 15 (1992) 819-834.
13. [13] W.J. Connick Jr., Controlled release of the herbicides 2,4-D and dichlobenil from alginate gels. J. Appl. Polym. Sci. 27 (1982) 3341-3348.
14. [14] W.J. Connick Jr., J.M. Bradow, W. Wells, K.K. Steward and T.K. Van, Preparation and evaluation of controlled release formulations of 2,6-dichlorobenzonitrile. J. Agric. Food Chem. 32 (1984) 1199-1205.
15. [15] A.B. Pepperman, J.W. Kuan and C. McCombs, Alginate controlled release formulation of metribuzin. J. Control. Release 17 (1991) 105-112.
16. [16] R.M. Wilkins and J.V. Cotterill, Evaluation of controlled release pesticide granules using a flow-through technique. Proc. Int. Symp. Control. Release Bioact. Mater. 20 (1993) 206-207.
17. [17] F. Alhaique, E. Beltrami, F. M. Riccieri, E. Santucci and E. Touitou, Scleroglucan sustained release oral preparations. Part II. Effects of additives. Drug Des. Deliv. 5 (1990) 249-257.
18. [18] F. Alhaique, M. Carafa, F.M. Riccieri, E. Santucci and E. Touitou, Studies on the release behaviour of a polysaccharide matrix. Pharmazie 48 (1993) 432-435.
19. [19] E. Touitou, F. Alhaique, F.M. Riccieri, G. Riccioni E. Santucci, Scleroglucan sustained release oral preparations. Part I. In vitro experiments. Drug Des. Deliv. 5 (1989) 141-148.
20. [20] A.T. Pham and P.I. Lee, Probing the mechanism of drug release from hydroxypropylmethylcellulose (HPMC) matrices. Proc. Int. Symp. Control. Release Bioact. Mater. 20 (1993) 220-221.
21. [21] R. Bettini, P. Colombo, G. Massimo, P. Santi, P.L. Catellani and N.A. Peppas, Moving fronts and drug release from hydrogel matrices. Proc. Int. Symp. Control. Release Bioact. Mater. 21 (1994) 19-20.
22. [22] T. Østberg, E.M. Lund and C. Graffner, Calcium alginate matrices for oral multiple unit administration. IV. Release characteristics in different media. Int. J. Pharm. 112 (1994) 241-248.