The antitumor effect of bromophenol derivatives in vitro and Leathesia nana extract in vivo

Chinese Journal of Oceanology and Limnology

Volumn 27, Issue 2, 2009, Pages 277-282

  Shi, Dayong ^a   Li, Jing ^a   Guo, Shuju ^a   Su, Hua ^a   Fan, Xiao ^a  

^a INSTITUTE OF OCEANOLOGY   (China)

Author keywords

antitumor; bromophenol derivatives; in vitro; in vivo; Leathesia nana

Indexed keywords

LEATHESIA NANA; MUS; PHAEOPHYCEAE;

EID: 79251478470     PISSN: 02544059     EISSN: 19935005     Source Type: Journal    
DOI: 10.1007/s00343-009-9119-x     Document Type: Article

References (31)

1. Arber, D. A., R. Tamayo and L. M. Weiss, 1998. Paraffin section detection of the c-kit gene production (CD117) in human tissues: value in the diagnosis of mast cell disorders. Hum. Pathol. 28: 498-504.
2. Bliss, C., 1935. The calculation of the dose-mortality curve. Ann. Appl. Biol. 22: 134-167.
3. Bokemeyer, C., M. A. Kuczyk, T. Dunn et al., 1996. Expression of stem-cell factor and its receptor c-kit protein in normal testicular tissue and malignant germ-cell tumors. J. Cancer Res. Clin. Oncol. 122: 301-306.
4. Carmichael, J., W. G. DeGraff, A. F. Gazdar et al., 1987. Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res. 47(4): 936-942.
5. Christiansen, D. H., M. K. Andersen, F. Desta et al., 2005. Mutations of genes in the receptor tyrosine kinase (RTK)/RASBRAF signal transduction pathway in therapy-related myelodysplasia and acute myeloid leukemia. Leukemia19(12): 2 232-2 240.
6. d'Auriol L., M. G. Mattei, C. Andre et al., 1988. Localization of the human c-kit protooncogene on the q11-q12 region of chromosome 4. Hum. Genet. 78: 374-376.
7. de Silva, C. M. and R. Reid, 2003. Gastrointestinal stromal tumors (GIST): c-kit mutations, CD117 expression, differential diagnosis and targeted cancer therapy with Imatinib. Pathol. Oncol. Res. 9(1): 13-19.
8. DeMatteo, R. P., 2002. The GIST of targeted cancer therapy: a tumor (gastrointestinal stromal tumor), a mutated gene (c-kit), and a molecular inhibitor (STI571). Ann. Surg. Oncol. 9(9): 831-839.
9. Demetri, G. D. 2001. Targeting c-kit mutations in solid tumors: scientific rationale and novel therapeutic options. Semin. Oncol. 28(5): 19-26.
10. Fan, X., N. J. Xu and J. G. Shi, 2003a. Bromophenols from the red agla Rhodomela confervoides. J. Nat. Prod. 66: 455-458.
11. Fan, X., N. J. Xu and J. G. Shi, 2003b. Two new bromophenols from red alga Rhodomela confervoids. Chin. Chem. Lett. 14(9): 939-941.
12. Fan, X., N. J. Xu and J. G. Shi, 2003c. A new brominated phenylpropylaldehyde and its dimethyl acetal from red alga rhodomela confervoides. Chin. Chem. Lett. 14(10): 1 045-1 047.
13. Hirota, S., T. Nishida, K. Isozaki et al., 2002. Familial gastrointestinal stromal tumors associated with dysphagia and novel type germline mutation of Kit gene. Gastroenterology. 122(5): 1 493-1 499.
14. Huang, Z. G. 1994. Marine Species and Their Distributions in China's Seas. China Ocean Press, Beijing, China. p. 217. (in Chinese).
15. Ikeda, H., Y. Kanakura, T. Tamaki, et al., 1991. Expression and functional role of the proto-oncogene c-kit in acute myeloblastic leukemia cells. Blood78(11): 2 962-2 968.
16. Longley, J. B., D. D. Metcalfe, M. Tharp, et al., 1999. Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis. Proc. Natl. Acad. Sci. USA. 96(4): 1 609-1 614.
17. Majumder, S., K. Brown, F. H. Qiu et al., 1988. C-kit protein, a transmembrane identification in tissues and characterization. Mol. Cell Biol. 8: 4 896-4 903.
18. McCulloch, E. A. and M. D. Minden, 1993. The cell surface receptor encoded by the proto-oncogene KIT and its ligand. Cancer Treat Res. 64: 45-77.
19. Miettinen, M. and J. Lasota, 2005. KIT (CD117): A review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation. Appl. Immunohistochem. Mol. Morphol. 13(3): 205-220.
20. Mosumann, T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods65(1): 55-63.
21. Pietsch, T., M. R. Nicotra, R. Fraioli et al., 1998. Expression of the c- Kit receptor and its ligand SCF in non-small-cell lung carcinomas. Int. J. Cancer. 75(2): 171-175.
22. Sarlomo-Rikala, M., A. J. Kovatich, A. Barusevicius et al., 1998. CD117: a sensitive marker for gastrointestinal stromal tumors that is more specific than CD34. Mod. Pathol. 11(8): 728-734.
23. Schmandt, R. E., R. Broaddus, K. H. Lu et al., 2003. Expression of c- ABL, c-KIT, and platelet-derived growth factor receptorbeta in ovarian serous carcinoma and normal ovarian surface epithelium. Cancer98(4): 758-764.
24. Tajima, F., T. Kawatani, K. Ishiga et al., 1998. Serum soluble c-kit receptor and expression of c-kit protein and mRNA in acute myeloid leukemia. Eur. J. Haematol. 60: 289-296.
25. Vitali, R., V. Cesi, M. R. Nicotra et al., 2003. C-Kit is preferentially expressed in MYCN-amplified neuroblastoma and its effect on cell proliferation is inhibited in vitro by STI-571. Int. J. Cancer106(2): 147-152.
26. Vliagoftis, H., A. S. Worobec and D. D. Metcalfe, 1997. The protooncogene c-kit and c-kit ligand in human disease. J. Allergy. Clin. Immunol. 100(4): 435-440.
27. Xu, N. J., X. Fan, X. J. Yan et al., 2003. Antibacterial bromophenols from the marine red alga Rhodomela confervoids. Phytochemistry62: 1 221-1 224.
28. Xu, X. L., F. H. Song, S. J. Wang et al., 2004a. Dibenzyl Bromophenols with Diverse Dimerization Patterns from the Brown Alga Leathesia nana. J. Nat. Prod. 67(10): 1 661-1 666.
29. Xu, X. L., X. Fan, F. H. Song et al., 2004b. A new bromophenol from the brown alga Leathesia nana. Chin. Chem. Lett. 15(6): 661-663.
30. Zhao, J. L, X. Fan, S. J. Wang et al., 2004. Bromophenol derivatives from the red alga Rhodomela confervoids J. Nat. Prod. 67: 1 032-1 035.
31. Zhao, J. L, M. Ma, S. J. Wang et al., 2005. Bromophenols coupled with derivatives of amino acids and nucleosides from the red alga Rhodomela confervoids J. Nat. Prod. 68: 691-694.