Paraffin section detection of the c-kit gene product (cd117) in human tissues: Value in the diagnosis of mast cell disorders

Human Pathology

Volumn 29, Issue 5, 1998, Pages 498-504

  Arber, Daniel A ^a   Tamayo, Rosalba ^a   Weiss, Lawrence M ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

C kit; CD 117; Immunohistochemistry; Mast cell disease; Mast cells

Indexed keywords

STEM CELL FACTOR RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC VALUE; ENDOMETRIUM CARCINOMA; GERM CELL TUMOR; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MAST CELL; MELANOMA; OVARY CARCINOMA; PROTO ONCOGENE; SMALL CELL CARCINOMA; THYROID FOLLICULAR CARCINOMA; THYROID PAPILLARY CARCINOMA;

EID: 0031923720     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0046-8177(98)90066-1     Document Type: Article

References (33)

1. Besmer P, Murphy JE, George PC, et al: A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family. Nature 320:415-421, 1986
2. Yarden Y, Kuang W-J, Yang-Feng T, et al: Human protooncogen c-kit: A new cell surface receptor tyrosine kinase for an unidentified ligand. EMBO J 6:3341-3351, 1987
3. Qiu F, Ray P, Brown K, et al: Primary structure of c-kit: Relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus. EMBO J 7:1003-1011, 1988
4. de Vries C, Escobedo JA, Ueno H, et al: The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255:898-991, 1992
5. Huang E, Nocka K, Beier DR, et al: The hematopoietic growth factor KL is encoded by SI locus and is the ligand of the c-kit receptor, the gene product of the Wlocus. Cell 63:225-233, 1990
6. Witte ON: Steel locus defines new multipotent growth factor. Cell 63:5-6, 1990
7. Zsebo KM, Williams DA, Geissler EN, et al: Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor. Cell 63:213-224, 1990
8. Anderson DM, Lyman SD, Baird A, et al: Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms. Cell 63:235-243, 1990
9. Nocka K, Majumder S, Chabot B, et al: Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice: Evidence for an impaired c-kit kinase in mutant mice. Genes Dev 3:816-826, 1989
10. Natali PG, Nicotra MR, Sures I, et al: Expression of c-kit receptor in normal and transformed human nonlymphoid tissues. Cancer Res 52:6139-6143, 1992
11. Matsuda R, Takahashi T, Nakamura S, et al: Expression of the c-kit protein in human solid tumors and in corresponding fetal and adult normal tissues. Am J Pathol 142:339-346, 1993
12. Lammie A, Drobnjak M, Gerald W, et al: Expression of c-kit and kit ligand proteins in normal human tissues. J Histochem Cytochem 42:1417-1425, 1994
13. Tsuura Y, Hiraki H, Watanabe K, et al: Preferential localization of c-kit product in tissue mast cells, basal cells of skin, epithelial cells of breast, small cell lung carcinoma and seminoma/dysgerminoma in human: Immunohistochemical study on formalin-fixed, paraffin-embedded tissues. Virchows Archiv A Pathol Anat 424:135-141, 1994
14. Wang C, Curtis JE, Geissler EN, et al: The expression of the proto-oncogene c-kit in the blast cells of acute myeloblastic leukemia. Leukemia 3:699-702, 1989
15. Ikeda H, Kanakura Y, Tamaki T, et al: Expression and functional role of the proto-oncogene c-kit in acute myeloblastic leukemia cells. Blood 78:2962-2968, 1991
16. Strohmeyer T, Peter S, Hartmann M, et al: Expression of the hst-1 and c-kit protooncogenes in human testicular germ cell tumors. Cancer Res 51:1811-1816, 1991
17. Hines SJ, Organ C, Kornstein MJ, et al: Coexpression of the c-kit and stem cell factor genes in breast carcinomas. Cell Growth Differ 6:769-779, 1995
18. Izquierdo MA, van der Valk P, van Ark-Otte J, et al: Differential expression of the c-kit proto-oncogene in germ cell tumours. J Pathol 177:253-258, 1995
19. Takahashi H, Saitoh K, Kishi H, et al: Immunohistochemical localisation of stem cell factor (SCF) with comparison of its receptor c-Kit proto-oncogene product (G-KIT) in melanocytic tumours. Virchows Arch A Pathol Anat 427:283-288, 1995
20. Ohashi A, Funasaka Y, Ueda M, et al: c-KIT receptor expression in cutaneous malignant melanoma and benign melanocytic naevi. Melanoma Research 6:25-30, 1996
21. Ridings J, Macardle PJ, Byard RW, et al: Cytokine receptor expression by solid tumours. Ther Immunol 2:67-76, 1995
22. Speights VO Jr, Cohen MK, Coffield KS, et al: Neuroendocrine staining in malignant, hyperplastic, and atrophic prostate tissue. Appl Immunohistochem 2:212-217, 1994
23. Battifora H, Mehta P: The checkerboard tissue block: An improved multitissue control block. Lab Invest 63:722-724, 1990
24. Sheibani K, Tubbs RR: Enzyme immunohistochemistry: Technical aspects. Semin Diagn Pathol 1:235-250, 1984
25. Battifora H, Alsabeh R, Jenkins KA, et al: Epitope retrieval (unmasking) in immunohistochemistry. Adv Pathol Lab Med 8:101-118, 1995
26. Natali PG, Nicotra MR, Sures I, et al: Breast cancer is associated with loss of the c-kit oncogene product. Int J Cancer 52:713-717, 1992
27. Natali PG, Nicotra MR, Winkler AB, et al: Progression of human cutaneous melanoma is associated with loss of expression of c-kit proto-oncogene receptor. Int J Cancer 52:197-201, 1992
28. Lassam N, Bickford S: Loss of c-kit expression in cultured melanoma cells. Oncogene 7:51-56, 1992
29. Natali PG, Berlingieri MT, Nicotra MR, et al: Transformation of thyroid epithelium is associated with loss of c-kit receptor. Cancer Res 55:1787-1791, 1995
30. Hibi K, Takahashi T, Sekido Y, et al: Coexpression of the stem cell factor and the c-kit genes in small-cell lung cancer. Oncogene 6:2291-2296, 1991
31. Plummer H III, Catlett J, Leftwich J, et al: c-myc expression correlates with suppression of c-kit protooncogene expression in small cell lung cancer cell lines. Cancer Res 53:4337-4342, 1993
32. Fukuda T, Kamishima T, Tsuura Y, et al: Expression of the c-kit gene product in normal and neoplastic mast cells but not in neoplastic basophil/mast cell precursors from chronic myelogenous leukaemia. J Pathol 177:139-146, 1995
33. Arber DA, Jenkins KA: Paraffin section immunophenotyping of acute leukemias in bone marrow specimens. Am J Clin Pathol 106:462-468, 1996