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Volumn 44, Issue 2-3, 2011, Pages 192-197

Simvastatin treatment reduces heat shock protein 60, 65, and 70 antibody titers in dyslipidemic patients: A randomized, double-blind, placebo-controlled, cross-over trial

Author keywords

Antibody; C reactive protein; Cross over study; Heat shock protein; Simvastatin

Indexed keywords

C REACTIVE PROTEIN; GLUCOSE; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 65; HEAT SHOCK PROTEIN 70; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; IMMUNOGLOBULIN G; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; SIMVASTATIN; TRIACYLGLYCEROL; CHAPERONIN 60; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

EID: 79151476825     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2010.09.016     Document Type: Article
Times cited : (17)

References (50)
  • 2
    • 0022555843 scopus 로고
    • The heat-shock response
    • Lindquist S. The heat-shock response. Annu Rev Biochem 1986, 55:1151-1191.
    • (1986) Annu Rev Biochem , vol.55 , pp. 1151-1191
    • Lindquist, S.1
  • 3
    • 0033554448 scopus 로고    scopus 로고
    • Association of serum antibodies to heat-shock protein 65 with carotid atherosclerosis: clinical significance determined in a follow-up study
    • Xu Q., Kiechl S., Mayr M., Metzler B., Egger G., Oberhollenzer F., et al. Association of serum antibodies to heat-shock protein 65 with carotid atherosclerosis: clinical significance determined in a follow-up study. Circulation 1999, 100:1169-1174.
    • (1999) Circulation , vol.100 , pp. 1169-1174
    • Xu, Q.1    Kiechl, S.2    Mayr, M.3    Metzler, B.4    Egger, G.5    Oberhollenzer, F.6
  • 4
    • 0035957031 scopus 로고    scopus 로고
    • Antibodies to human heat-shock protein 60 are associated with the presence and severity of coronary artery disease: evidence for an autoimmune component of atherogenesis
    • Zhu J., Quyyumi A.A., Rott D., Csako G., Wu H., Halcox J., et al. Antibodies to human heat-shock protein 60 are associated with the presence and severity of coronary artery disease: evidence for an autoimmune component of atherogenesis. Circulation 2001, 103:1071-1075.
    • (2001) Circulation , vol.103 , pp. 1071-1075
    • Zhu, J.1    Quyyumi, A.A.2    Rott, D.3    Csako, G.4    Wu, H.5    Halcox, J.6
  • 5
  • 7
    • 0034604242 scopus 로고    scopus 로고
    • Serum soluble heat shock protein 60 is elevated in subjects with atherosclerosis in a general population
    • Xu Q., Schett G., Perschinka H., Mayr M., Egger G., Oberhollenzer F., et al. Serum soluble heat shock protein 60 is elevated in subjects with atherosclerosis in a general population. Circulation 2000, 102:14-20.
    • (2000) Circulation , vol.102 , pp. 14-20
    • Xu, Q.1    Schett, G.2    Perschinka, H.3    Mayr, M.4    Egger, G.5    Oberhollenzer, F.6
  • 8
    • 34547911390 scopus 로고    scopus 로고
    • Relationship between plasma cholesterol, von Willebrand factor concentrations, extent of atherosclerosis and antibody titres to heat shock proteins-60, -65 and -70 in cholesterol-fed rabbits
    • Ghayour-Mobarhan M., Lamb D.J., Tavallaie S., Ferns G.A. Relationship between plasma cholesterol, von Willebrand factor concentrations, extent of atherosclerosis and antibody titres to heat shock proteins-60, -65 and -70 in cholesterol-fed rabbits. Int J Exp Pathol 2007, 88:249-255.
    • (2007) Int J Exp Pathol , vol.88 , pp. 249-255
    • Ghayour-Mobarhan, M.1    Lamb, D.J.2    Tavallaie, S.3    Ferns, G.A.4
  • 9
    • 18744391956 scopus 로고    scopus 로고
    • The effects of prior beta-blocker therapy on serum C-reactive protein levels after percutaneous coronary intervention
    • Atar I., Gulmez O., Atar A., Bozbas H., Yildirir A., Ozin B., et al. The effects of prior beta-blocker therapy on serum C-reactive protein levels after percutaneous coronary intervention. Clin Cardiol 2005, 28:243-246.
    • (2005) Clin Cardiol , vol.28 , pp. 243-246
    • Atar, I.1    Gulmez, O.2    Atar, A.3    Bozbas, H.4    Yildirir, A.5    Ozin, B.6
  • 10
    • 0013879430 scopus 로고
    • The liver as the site of C-reactive protein formation
    • Hurlimann J., Thorbecke G.J., Hochwald G.M. The liver as the site of C-reactive protein formation. J Exp Med 1966, 123:365-378.
    • (1966) J Exp Med , vol.123 , pp. 365-378
    • Hurlimann, J.1    Thorbecke, G.J.2    Hochwald, G.M.3
  • 11
    • 0025765623 scopus 로고
    • Effects of cytokine combinations on acute phase protein production in two human hepatoma cell lines
    • Mackiewicz A., Speroff T., Ganapathi M.K., Kushner I. Effects of cytokine combinations on acute phase protein production in two human hepatoma cell lines. J Immunol 1991, 146:3032-3037.
    • (1991) J Immunol , vol.146 , pp. 3032-3037
    • Mackiewicz, A.1    Speroff, T.2    Ganapathi, M.K.3    Kushner, I.4
  • 12
    • 0037126012 scopus 로고    scopus 로고
    • Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells
    • Venugopal S.K., Devaraj S., Yuhanna I., Shaul P., Jialal I. Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells. Circulation 2002, 106:1439-1441.
    • (2002) Circulation , vol.106 , pp. 1439-1441
    • Venugopal, S.K.1    Devaraj, S.2    Yuhanna, I.3    Shaul, P.4    Jialal, I.5
  • 13
    • 0036157628 scopus 로고    scopus 로고
    • C-reactive protein and cardiovascular disease: a review of risk prediction and interventions
    • de Ferranti S., Rifai N. C-reactive protein and cardiovascular disease: a review of risk prediction and interventions. Clin Chim Acta 2002, 317:1-15.
    • (2002) Clin Chim Acta , vol.317 , pp. 1-15
    • de Ferranti, S.1    Rifai, N.2
  • 14
    • 0037197780 scopus 로고    scopus 로고
    • Elevated C-reactive protein values and atherosclerosis in sudden coronary death: association with different pathologies
    • Burke A.P., Tracy R.P., Kolodgie F., Malcom G.T., Zieske A., Kutys R., et al. Elevated C-reactive protein values and atherosclerosis in sudden coronary death: association with different pathologies. Circulation 2002, 105:2019-2023.
    • (2002) Circulation , vol.105 , pp. 2019-2023
    • Burke, A.P.1    Tracy, R.P.2    Kolodgie, F.3    Malcom, G.T.4    Zieske, A.5    Kutys, R.6
  • 15
    • 0032566401 scopus 로고    scopus 로고
    • Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women
    • Ridker P.M., Buring J.E., Shih J., Matias M., Hennekens C.H. Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women. Circulation 1998, 98:731-733.
    • (1998) Circulation , vol.98 , pp. 731-733
    • Ridker, P.M.1    Buring, J.E.2    Shih, J.3    Matias, M.4    Hennekens, C.H.5
  • 16
    • 0030956673 scopus 로고    scopus 로고
    • Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men
    • Ridker P.M., Cushman M., Stampfer M.J., Tracy R.P., Hennekens C.H. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 1997, 336:973-979.
    • (1997) N Engl J Med , vol.336 , pp. 973-979
    • Ridker, P.M.1    Cushman, M.2    Stampfer, M.J.3    Tracy, R.P.4    Hennekens, C.H.5
  • 17
    • 0030979827 scopus 로고    scopus 로고
    • Relationship of C-reactive protein to risk of cardiovascular disease in the elderly. Results from the Cardiovascular Health Study and the Rural Health Promotion Project
    • Tracy R.P., Lemaitre R.N., Psaty B.M., Ives D.G., Evans R.W., Cushman M., et al. Relationship of C-reactive protein to risk of cardiovascular disease in the elderly. Results from the Cardiovascular Health Study and the Rural Health Promotion Project. Arterioscler Thromb Vasc Biol 1997, 17:1121-1127.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 1121-1127
    • Tracy, R.P.1    Lemaitre, R.N.2    Psaty, B.M.3    Ives, D.G.4    Evans, R.W.5    Cushman, M.6
  • 18
    • 0028909230 scopus 로고
    • Hemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group
    • Thompson S.G., Kienast J., Pyke S.D., Haverkate F., van de Loo J.C. Hemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group. N Engl J Med 1995, 332:635-641.
    • (1995) N Engl J Med , vol.332 , pp. 635-641
    • Thompson, S.G.1    Kienast, J.2    Pyke, S.D.3    Haverkate, F.4    van de Loo, J.C.5
  • 20
    • 12944270424 scopus 로고    scopus 로고
    • Heat shock protein antibody titers are reduced by statin therapy in dyslipidemic subjects: a pilot study
    • Ghayour-Mobarhan M., Lamb D.J., Vaidya N., Livingstone C., Wang T., Ferns G.A. Heat shock protein antibody titers are reduced by statin therapy in dyslipidemic subjects: a pilot study. Angiology 2005, 56:61-68.
    • (2005) Angiology , vol.56 , pp. 61-68
    • Ghayour-Mobarhan, M.1    Lamb, D.J.2    Vaidya, N.3    Livingstone, C.4    Wang, T.5    Ferns, G.A.6
  • 21
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group
    • Shepherd J., Cobbe S.M., Ford I., Isles C.G., Lorimer A.R., MacFarlane P.W., et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group. N Engl J Med 1995, 333:1301-1307.
    • (1995) N Engl J Med , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3    Isles, C.G.4    Lorimer, A.R.5    MacFarlane, P.W.6
  • 22
    • 0037840242 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial
    • Collins R., Armitage J., Parish S., Sleigh P., Peto R. MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. Lancet 2003, 361:2005-2016.
    • (2003) Lancet , vol.361 , pp. 2005-2016
    • Collins, R.1    Armitage, J.2    Parish, S.3    Sleigh, P.4    Peto, R.5
  • 23
    • 17744400708 scopus 로고    scopus 로고
    • Effects of statins on endothelium and endothelial progenitor cell recruitment
    • Walter D.H., Dimmeler S., Zeiher A.M. Effects of statins on endothelium and endothelial progenitor cell recruitment. Semin Vasc Med 2004, 4:385-393.
    • (2004) Semin Vasc Med , vol.4 , pp. 385-393
    • Walter, D.H.1    Dimmeler, S.2    Zeiher, A.M.3
  • 25
    • 0036034385 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors as immunomodulators: potential use in transplant rejection
    • Raggatt L.J., Partridge N.C. HMG-CoA reductase inhibitors as immunomodulators: potential use in transplant rejection. Drugs 2002, 62:2185-2191.
    • (2002) Drugs , vol.62 , pp. 2185-2191
    • Raggatt, L.J.1    Partridge, N.C.2
  • 26
    • 0037230935 scopus 로고    scopus 로고
    • Lymphocyte function-associated antigen-1 blockade by statins: molecular basis and biological relevance
    • Weitz-Schmidt G. Lymphocyte function-associated antigen-1 blockade by statins: molecular basis and biological relevance. Endothelium 2003, 10:43-47.
    • (2003) Endothelium , vol.10 , pp. 43-47
    • Weitz-Schmidt, G.1
  • 27
    • 31544446624 scopus 로고    scopus 로고
    • Plasma antibody titres to heat shock proteins-60, -65 and-70: their relationship to coronary risk factors in dyslipidaemic patients and healthy individuals
    • Ghayour-Mobarhan M., Lamb D.J., Lovell D.P., Livingstone C., Wang T., Ferns G.A. Plasma antibody titres to heat shock proteins-60, -65 and-70: their relationship to coronary risk factors in dyslipidaemic patients and healthy individuals. Scand J Clin Lab Investig 2005, 65:601-614.
    • (2005) Scand J Clin Lab Investig , vol.65 , pp. 601-614
    • Ghayour-Mobarhan, M.1    Lamb, D.J.2    Lovell, D.P.3    Livingstone, C.4    Wang, T.5    Ferns, G.A.6
  • 28
    • 0142124353 scopus 로고    scopus 로고
    • Differential effects of statins on serum CRP levels: implications of recent clinical trials
    • Ferns G.A. Differential effects of statins on serum CRP levels: implications of recent clinical trials. Atherosclerosis 2003, 169:349-351.
    • (2003) Atherosclerosis , vol.169 , pp. 349-351
    • Ferns, G.A.1
  • 29
    • 33845364560 scopus 로고    scopus 로고
    • Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease
    • Petkova S.B., Akilesh S., Sproule T.J., Christianson G.J., Al Khabbaz H., Brown A.C., et al. Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease. Int Immunol 2006, 18:1759-1769.
    • (2006) Int Immunol , vol.18 , pp. 1759-1769
    • Petkova, S.B.1    Akilesh, S.2    Sproule, T.J.3    Christianson, G.J.4    Al Khabbaz, H.5    Brown, A.C.6
  • 30
    • 0013826882 scopus 로고
    • Studies on the catabolism of gamma-G subunits and chains
    • Spiegelberg H.L., Weigle W.O. Studies on the catabolism of gamma-G subunits and chains. J Immunol 1965, 95:1034.
    • (1965) J Immunol , vol.95 , pp. 1034
    • Spiegelberg, H.L.1    Weigle, W.O.2
  • 31
    • 0015327927 scopus 로고
    • The catabolism of human G immunoglobulins of different heavy chain subclasses. 3. The catabolism of heavy chain disease proteins and of Fc fragments of myeloma proteins
    • Spiegelberg H.L., Fishkin B.G. The catabolism of human G immunoglobulins of different heavy chain subclasses. 3. The catabolism of heavy chain disease proteins and of Fc fragments of myeloma proteins. Clin Exp Immunol 1972, 10:599.
    • (1972) Clin Exp Immunol , vol.10 , pp. 599
    • Spiegelberg, H.L.1    Fishkin, B.G.2
  • 33
    • 0014770620 scopus 로고
    • Metabolic properties of IgG subclasses in man
    • Morell A., Terry W.D., Waldmann T.A. Metabolic properties of IgG subclasses in man. J Clin Invest 1970, 49:673.
    • (1970) J Clin Invest , vol.49 , pp. 673
    • Morell, A.1    Terry, W.D.2    Waldmann, T.A.3
  • 34
    • 63349098488 scopus 로고    scopus 로고
    • Reduction of heat shock protein antibody levels by statin therapy
    • Guisasola M.C., Dulin E., Almendral J., Garcia-Barreno P. Reduction of heat shock protein antibody levels by statin therapy. Lipids 2009, 44:317-324.
    • (2009) Lipids , vol.44 , pp. 317-324
    • Guisasola, M.C.1    Dulin, E.2    Almendral, J.3    Garcia-Barreno, P.4
  • 35
    • 33751187656 scopus 로고    scopus 로고
    • Effect of cardiac rehabilitation and statin treatment on anti-HSP antibody titers in patients with coronary artery disease after percutaneous coronary intervention
    • Shin Y.O., Bae J.S., Lee J.B., Kim J.K., Kim Y.J., Kim C., et al. Effect of cardiac rehabilitation and statin treatment on anti-HSP antibody titers in patients with coronary artery disease after percutaneous coronary intervention. Int Heart J 2006, 47:671-682.
    • (2006) Int Heart J , vol.47 , pp. 671-682
    • Shin, Y.O.1    Bae, J.S.2    Lee, J.B.3    Kim, J.K.4    Kim, Y.J.5    Kim, C.6
  • 36
    • 0032757209 scopus 로고    scopus 로고
    • Atorvastatin reduces NF-kappaB activation and chemokine expression in vascular smooth muscle cells and mononuclear cells
    • Ortego M., Bustos C., Hernandez-Presa M.A., Tunon J., Diaz C., Hernandez G., et al. Atorvastatin reduces NF-kappaB activation and chemokine expression in vascular smooth muscle cells and mononuclear cells. Atherosclerosis 1999, 147:253-261.
    • (1999) Atherosclerosis , vol.147 , pp. 253-261
    • Ortego, M.1    Bustos, C.2    Hernandez-Presa, M.A.3    Tunon, J.4    Diaz, C.5    Hernandez, G.6
  • 37
    • 0242661386 scopus 로고    scopus 로고
    • Efficacy of fenofibrate and simvastatin on endothelial function and inflammatory markers in patients with combined hyperlipidemia: relations with baseline lipid profiles
    • Wang T.D., Chen W.J., Lin J.W., Cheng C.C., Chen M.F., Lee Y.T. Efficacy of fenofibrate and simvastatin on endothelial function and inflammatory markers in patients with combined hyperlipidemia: relations with baseline lipid profiles. Atherosclerosis 2003, 170:315-323.
    • (2003) Atherosclerosis , vol.170 , pp. 315-323
    • Wang, T.D.1    Chen, W.J.2    Lin, J.W.3    Cheng, C.C.4    Chen, M.F.5    Lee, Y.T.6
  • 38
    • 1642405502 scopus 로고    scopus 로고
    • Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells
    • Mulhaupt F., Matter C.M., Kwak B.R., Pelli G., Veillard N.R., Burger F., et al. Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells. Cardiovasc Res 2003, 59:755-766.
    • (2003) Cardiovasc Res , vol.59 , pp. 755-766
    • Mulhaupt, F.1    Matter, C.M.2    Kwak, B.R.3    Pelli, G.4    Veillard, N.R.5    Burger, F.6
  • 39
    • 70349258349 scopus 로고    scopus 로고
    • Immunomodulation by statins: mechanisms and potential impact on autoimmune diseases
    • Chow S.C. Immunomodulation by statins: mechanisms and potential impact on autoimmune diseases. Arch Immunol Ther Exp (Warsz) 2009, 57:243-251.
    • (2009) Arch Immunol Ther Exp (Warsz) , vol.57 , pp. 243-251
    • Chow, S.C.1
  • 40
    • 0037629751 scopus 로고    scopus 로고
    • Relationship between effects of statins, aspirin and angiotensin II modulators on high-sensitive C-reactive protein levels
    • Takeda T., Hoshida S., Nishino M., Tanouchi J., Otsu K., Hori M. Relationship between effects of statins, aspirin and angiotensin II modulators on high-sensitive C-reactive protein levels. Atherosclerosis 2003, 169:155-158.
    • (2003) Atherosclerosis , vol.169 , pp. 155-158
    • Takeda, T.1    Hoshida, S.2    Nishino, M.3    Tanouchi, J.4    Otsu, K.5    Hori, M.6
  • 41
    • 0033537351 scopus 로고    scopus 로고
    • Effect of statins on C-reactive protein in patients with coronary artery disease
    • Strandberg T.E., Vanhanen H., Tikkanen M.J. Effect of statins on C-reactive protein in patients with coronary artery disease. Lancet 1999, 353:118-119.
    • (1999) Lancet , vol.353 , pp. 118-119
    • Strandberg, T.E.1    Vanhanen, H.2    Tikkanen, M.J.3
  • 42
    • 0035901619 scopus 로고    scopus 로고
    • Effect of hydroxymethyl glutaryl coenzyme a reductase inhibitor therapy on high sensitive C-reactive protein levels
    • Jialal I., Stein D., Balis D., Grundy S.M., ms-Huet B., Devaraj S. Effect of hydroxymethyl glutaryl coenzyme a reductase inhibitor therapy on high sensitive C-reactive protein levels. Circulation 2001, 103:1933-1935.
    • (2001) Circulation , vol.103 , pp. 1933-1935
    • Jialal, I.1    Stein, D.2    Balis, D.3    Grundy, S.M.4    ms-Huet, B.5    Devaraj, S.6
  • 43
    • 33846856622 scopus 로고    scopus 로고
    • C-reactive protein (CRP)-lowering agents
    • Prasad K. C-reactive protein (CRP)-lowering agents. Cardiovasc Drug Rev 2006, 24:33-50.
    • (2006) Cardiovasc Drug Rev , vol.24 , pp. 33-50
    • Prasad, K.1
  • 44
    • 0035814945 scopus 로고    scopus 로고
    • Rapid reduction in C-reactive protein with cerivastatin among 785 patients with primary hypercholesterolemia
    • Ridker P.M., Rifai N., Lowenthal S.P. Rapid reduction in C-reactive protein with cerivastatin among 785 patients with primary hypercholesterolemia. Circulation 2001, 103:1191-1193.
    • (2001) Circulation , vol.103 , pp. 1191-1193
    • Ridker, P.M.1    Rifai, N.2    Lowenthal, S.P.3
  • 45
    • 0035806626 scopus 로고    scopus 로고
    • Effect of statin therapy on C-reactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study
    • Albert M.A., Danielson E., Rifai N., Ridker P.M. Effect of statin therapy on C-reactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study. JAMA 2001, 286:64-70.
    • (2001) JAMA , vol.286 , pp. 64-70
    • Albert, M.A.1    Danielson, E.2    Rifai, N.3    Ridker, P.M.4
  • 46
    • 0033587667 scopus 로고    scopus 로고
    • Long-term effects of pravastatin on plasma concentration of C-reactive protein. The Cholesterol and Recurrent Events (CARE) Investigators
    • Ridker P.M., Rifai N., Pfeffer M.A., Sacks F., Braunwald E. Long-term effects of pravastatin on plasma concentration of C-reactive protein. The Cholesterol and Recurrent Events (CARE) Investigators. Circulation 1999, 100:230-235.
    • (1999) Circulation , vol.100 , pp. 230-235
    • Ridker, P.M.1    Rifai, N.2    Pfeffer, M.A.3    Sacks, F.4    Braunwald, E.5
  • 47
    • 54949120935 scopus 로고    scopus 로고
    • Effect of HMG CoA reductase inhibitors on low-density lipoprotein cholesterol and C-reactive protein: systematic review and meta-analysis
    • Genser B., Grammer T.B., Stojakovic T., Siekmeier R., Marz W. Effect of HMG CoA reductase inhibitors on low-density lipoprotein cholesterol and C-reactive protein: systematic review and meta-analysis. Int J Clin Pharmacol Ther 2008, 46:497-510.
    • (2008) Int J Clin Pharmacol Ther , vol.46 , pp. 497-510
    • Genser, B.1    Grammer, T.B.2    Stojakovic, T.3    Siekmeier, R.4    Marz, W.5
  • 48
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90, 056 participants in 14 randomised trials of statins
    • Baigent C., Keech A., Kearney P.M., Blackwell L., Buck G., Pollicino C., et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90, 056 participants in 14 randomised trials of statins. Lancet 2005, 366:1267-1278.
    • (2005) Lancet , vol.366 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3    Blackwell, L.4    Buck, G.5    Pollicino, C.6
  • 49
    • 77649257891 scopus 로고    scopus 로고
    • The influence of simvastatin on selected inflammatory markers in patients with chronic obstructive pulmonary disease
    • Kaczmarek P., Sładek K., Skucha W., Rzeszutko M., Iwaniec T., Dziedzina S., et al. The influence of simvastatin on selected inflammatory markers in patients with chronic obstructive pulmonary disease. Pol Arch Med Wewn 2010, 120:11-18.
    • (2010) Pol Arch Med Wewn , vol.120 , pp. 11-18
    • Kaczmarek, P.1    Sładek, K.2    Skucha, W.3    Rzeszutko, M.4    Iwaniec, T.5    Dziedzina, S.6
  • 50
    • 77953285999 scopus 로고    scopus 로고
    • Pitavastatin reduces lectin-like oxidized low-density lipoprotein receptor-1 ligands in hypercholesterolemic humans
    • Matsumoto T., Fujita M., Sawamura T., Kakino A., Sato Y., Fujita Y., et al. Pitavastatin reduces lectin-like oxidized low-density lipoprotein receptor-1 ligands in hypercholesterolemic humans. Lipids 2010, 45:329-335.
    • (2010) Lipids , vol.45 , pp. 329-335
    • Matsumoto, T.1    Fujita, M.2    Sawamura, T.3    Kakino, A.4    Sato, Y.5    Fujita, Y.6


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